Patents by Inventor James A. Beatty

James A. Beatty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11492579
    Abstract: High-throughput column arrays of vascularized living parenchyma/tissue having pillars dispersed in specialized configurations and arrangements substantially vertically through the column to provide support, passive or active perfusion, and access to internal portions of tissue for analytical sampling needs, along with 3-D printing methods of manufacture and analytical screening methods employing the column arrays.
    Type: Grant
    Filed: April 13, 2018
    Date of Patent: November 8, 2022
    Assignee: Advanced Solutions Life Sciences, LLC
    Inventor: James Beatty Hoying
  • Publication number: 20210214662
    Abstract: High-throughput column arrays of vascularized living parenchyma/tissue having pillars dispersed in specialized configurations and arrangements substantially vertically through the column to provide support, passive or active perfusion, and access to internal portions of tissue for analytical sampling needs, along with 3-D printing methods of manufacture and analytical screening methods employing the column arrays.
    Type: Application
    Filed: April 13, 2018
    Publication date: July 15, 2021
    Inventor: James Beatty Hoying
  • Patent number: 10457929
    Abstract: The present invention provides compositions for use in the prophylaxis or treatment of a condition arising from gluten intolerance, the compositions including at least partially purified caricain (or a biologically active fragment, analogue or variant thereof) alone or in combination with other suitable enzymes including bromelain, and/or an intestinal extract, as herein described. The present invention also provides methods of using such compositions for the prophylaxis or treatment of a condition arising from gluten intolerance.
    Type: Grant
    Filed: September 24, 2018
    Date of Patent: October 29, 2019
    Assignee: Glutagen Pty Ltd.
    Inventors: Teodor Stelmasiak, Hugh James Beatty Cornell
  • Patent number: 10414859
    Abstract: Polyester polyols made from thermoplastic polyesters are disclosed. The polyols are reaction products of a thermoplastic polyester, a glycol, and a hydrophobe selected from ricinoleic acid, ethoxylated castor oil, saturated or unsaturated C9-C18 dicarboxylic acids, tung oil, soybean oil, sunflower oil, cardanol-based products, recycled cooking oil, isostearyl alcohol, hydroxy-functional materials derived from epoxidized, ozonized, or hydroformylated fatty esters or fatty acids, and mixtures thereof. In one process, the polyols are made by reacting the thermoplastic polyester with a glycol to give a digested intermediate, which is then reacted with the hydrophobe. In another process, the thermoplastic polyester, glycol, and hydrophobe are combined and reacted in a single step. These hydrophobes facilitate the production from recycled thermoplastics of polyols that have good transparency and little or no particulate settling or phase separation.
    Type: Grant
    Filed: October 19, 2015
    Date of Patent: September 17, 2019
    Assignee: RESINATE MATERIALS GROUP, INC.
    Inventors: Rick Tabor, Kevin Anthony Rogers, Eric D Vrabel, Matthew James Beatty, Woo-Sung Bae, Shakti L Mukerjee
  • Publication number: 20190010477
    Abstract: The present invention provides compositions for use in the prophylaxis or treatment of a condition arising from gluten intolerance, the compositions including at least partially purified caricain (or a biologically active fragment, analogue or variant thereof) alone or in combination with other suitable enzymes including bromelain, and/or an intestinal extract, as herein described. The present invention also provides methods of using such compositions for the prophylaxis or treatment of a condition arising from gluten intolerance.
    Type: Application
    Filed: September 24, 2018
    Publication date: January 10, 2019
    Inventors: Teodor Stelmasiak, Hugh James Beatty Cornell
  • Patent number: 10100296
    Abstract: The present invention provides compositions for use in the prophylaxis or treatment of a condition arising from gluten intolerance, the compositions including at least partially purified caricain (or a biologically active fragment, analog or variant thereof) alone or in combination with other suitable enzymes including bromelain, and/or an intestinal extract, as herein described. The present invention also provides methods of using such compositions for the prophylaxis or treatment of a condition arising from gluten intolerance.
    Type: Grant
    Filed: January 6, 2010
    Date of Patent: October 16, 2018
    Assignee: Glutagen Pty Ltd
    Inventors: Teodor Stelmasiak, Hugh James Beatty Cornell
  • Patent number: 9988489
    Abstract: Polyester polyols, processes for making them, and applications for the polyols are disclosed. In some aspects, the polyols comprise recurring units from a thermoplastic polyester or an aromatic polyacid source, a glycol, and a lignin, tannin, or mixture thereof. Optionally, the polyols incorporate recurring units of a hydrophobe. The polyols are made in one or multiple steps; in some aspects, the thermoplastic polyester or aromatic polyacid source and the glycol are reacted first, followed by reaction with the lignin, tannin, or mixture thereof. High-recycle-content polyols having desirable properties and attributes for formulating polyurethane products, including two-component polyurethane coatings, can be made. The polyols provide a sustainable alternative to bio- or petrochemical-based polyols.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: June 5, 2018
    Assignee: Resinate Materials Group, Inc.
    Inventors: Shakti Mukerjee, Kevin Anthony Rogers, Matthew James Beatty, Gary E. Spilman
  • Publication number: 20170335057
    Abstract: Polyester polyols, processes for making them, and applications for the polyols are disclosed. In some aspects, the polyols comprise recurring units from a thermoplastic polyester or an aromatic polyacid source, a glycol, and a hydroxy-functional ketal acid, ester or amide. Optionally, the polyols incorporate recurring units of a hydrophobe. The polyols are made in one or multiple steps; in some aspects, the thermoplastic polyester or aromatic polyacid source and the glycol are reacted first, followed by reaction with the hydroxy-functional ketal acid, ester or amide. The resulting polyols have good transparency and little or no particulate settling or phase separation. High-recycle-content polyols having desirable properties and attributes for formulating polyurethane products, including aqueous polyurethane dispersions, flexible and rigid foams, coatings, adhesives, sealants, and elastomers can be made. The polyols provide a sustainable alternative to bio- or petrochemical-based polyols.
    Type: Application
    Filed: October 27, 2015
    Publication date: November 23, 2017
    Inventors: Rick Tabor, Eric David Vrabel, Kevin Anthony Rogers, Matthew James Beatty, Woo-Sung Bae, Jack Rogers Kovsky, Michael Robert Christy
  • Publication number: 20170327638
    Abstract: Polyester polyols, processes for making them, and applications for the polyols are disclosed. In some aspects, the polyols comprise recurring units from a thermoplastic polyester or an aromatic polyacid source, a glycol, and a lignin, tannin, or mixture thereof. Optionally, the polyols incorporate recurring units of a hydrophobe. The polyols are made in one or multiple steps; in some aspects, the thermoplastic polyester or aromatic polyacid source and the glycol are reacted first, followed by reaction with the lignin, tannin, or mixture thereof. High-recycle-content polyols having desirable properties and attributes for formulating polyurethane products, including two-component polyurethane coatings, can be made. The polyols provide a sustainable alternative to bio- or petrochemical-based polyols.
    Type: Application
    Filed: July 31, 2017
    Publication date: November 16, 2017
    Inventors: Shakti Mukerjee, Kevin Anthony Rogers, Matthew James Beatty, Gary E. Spilman
  • Patent number: 9751978
    Abstract: Polyester polyols, processes for making them, and applications for the polyols are disclosed. In some aspects, the polyols comprise recurring units from a thermoplastic polyester or an aromatic polyacid source, a glycol, and a lignin, tannin, or mixture thereof. Optionally, the polyols incorporate recurring units of a hydrophobe. The polyols are made in one or multiple steps; in some aspects, the thermoplastic polyester or aromatic polyacid source and the glycol are reacted first, followed by reaction with the lignin, tannin, or mixture thereof. High-recycle-content polyols having desirable properties and attributes for formulating polyurethane products, including two-component polyurethane coatings, can be made. The polyols provide a sustainable alternative to bio- or petrochemical-based polyols.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: September 5, 2017
    Assignee: Resinate Materials Group, Inc.
    Inventors: Shakti Mukerjee, Kevin Anthony Rogers, Matthew James Beatty, Gary E. Spilman
  • Patent number: 9732026
    Abstract: The presently disclosed and/or claimed inventive concept(s) relates generally to oligomeric reaction products formed by the depolymerization of polyethylene terephthalate polymers and methods thereof. More specifically, the presently disclosed and/or claimed inventive concept(s) relates to oligomeric reaction products formed by the depolymerization of polyethylene terephthalate polymer obtained from, for example but not by way of limitation, waste products, such as beverage containers made from polyethylene terephthalate (PET). The oligomeric reaction products can, in one embodiment, be used as a starting material for polyurethanes. The presently disclosed and/or claimed inventive concept(s) also relates to processes for producing oligomeric reaction products from the depolymerization of polyethylene terephthalate.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: August 15, 2017
    Assignee: Resinate Technologies, Inc.
    Inventors: Rick Tabor, Daniel James Seyer, Kristopher M Felice, Adam W Emerson, Matthew Thomas Brown, Kyle Harris McGrath, Mickey Kellerman, Kevin Anthony Rogers, Jack Rogers Kovsky, Matthew James Beatty, Eric David Vrabel
  • Publication number: 20170002138
    Abstract: Polyester polyols, processes for making them, and applications for the polyols are disclosed. In some aspects, the polyols comprise recurring units from a thermoplastic polyester or an aromatic polyacid source, a glycol, and a lignin, tannin, or mixture thereof. Optionally, the polyols incorporate recurring units of a hydrophobe. The polyols are made in one or multiple steps; in some aspects, the thermoplastic polyester or aromatic polyacid source and the glycol are reacted first, followed by reaction with the lignin, tannin, or mixture thereof. High-recycle-content polyols having desirable properties and attributes for formulating polyurethane products, including two-component polyurethane coatings, can be made. The polyols provide a sustainable alternative to bio- or petrochemical-based polyols.
    Type: Application
    Filed: September 15, 2016
    Publication date: January 5, 2017
    Inventors: Shakti Mukerjee, Kevin Anthony Rogers, Matthew James Beatty, Gary E. Spilman
  • Patent number: 9506035
    Abstract: The present invention generally relates to methods, compositions and uses thereof for enhancing vascularization of a tissue or cell transplant for transplantation into a subject. In particular, one aspect of the present invention provides methods and compositions comprising the use of a population of stromal vascular fraction (SVF) cells to encapsulate or surround a tissue or cell transplant to enhance vascularization of the tissue or cell transplant. Another aspect of the present invention provides methods and compositions for enhancing vascularization of a tissue or cell transplant by combining a population of SVF cells with a tissue or cell transplant to form a transplant mixed with SVF cells. In some embodiments, the SVF cells can be on the surface or embedded within a three-dimensional matrix. In some embodiments, the SVF cells can be generically engineered to secrete therapeutic proteins or pro-angiogenic factors.
    Type: Grant
    Filed: October 13, 2010
    Date of Patent: November 29, 2016
    Assignee: University of Louisville Research Foundation, Inc
    Inventors: Stuart K. Williams, James Beatty Hoying, Laxminarayanan Krishnan
  • Patent number: 9481760
    Abstract: Polyester polyols, processes for making them, and applications for the polyols are disclosed. In some aspects, the polyols comprise recurring units from a thermoplastic polyester or an aromatic polyacid source, a glycol, and a lignin, tannin, or mixture thereof. Optionally, the polyols incorporate recurring units of a hydrophobe. The polyols are made in one or multiple steps; in some aspects, the thermoplastic polyester or aromatic polyacid source and the glycol are reacted first, followed by reaction with the lignin, tannin, or mixture thereof. High-recycle-content polyols having desirable properties and attributes for formulating polyurethane products, including two-component polyurethane coatings, can be made. The polyols provide a sustainable alternative to bio- or petrochemical-based polyols.
    Type: Grant
    Filed: March 24, 2016
    Date of Patent: November 1, 2016
    Assignee: Resinate Materials Group, Inc.
    Inventors: Shakti Mukerjee, Kevin Anthony Rogers, Matthew James Beatty, Gary E. Spilman
  • Publication number: 20160208044
    Abstract: Polyester polyols, processes for making them, and applications for the polyols are disclosed. In some aspects, the polyols comprise recurring units from a thermoplastic polyester or an aromatic polyacid source, a glycol, and a lignin, tannin, or mixture thereof. Optionally, the polyols incorporate recurring units of a hydrophobe. The polyols are made in one or multiple steps; in some aspects, the thermoplastic polyester or aromatic polyacid source and the glycol are reacted first, followed by reaction with the lignin, tannin, or mixture thereof. High-recycle-content polyols having desirable properties and attributes for formulating polyurethane products, including two-component polyurethane coatings, can be made. The polyols provide a sustainable alternative to bio- or petrochemical-based polyols.
    Type: Application
    Filed: March 24, 2016
    Publication date: July 21, 2016
    Inventors: Shakti Mukerjee, Kevin Anthony Rogers, Matthew James Beatty, Gary E. Spilman
  • Patent number: 9389292
    Abstract: A system and method for combining k-space data acquired on multiple different receiver channels in a multichannel receiver is provided. One or more convolution kernels are used to combine the k-space data. Each convolution kernel is designed as the combination of one or more channel combination kernels and an alias-suppressing kernel. The channel combination kernels are designed to have a smaller sample spacing than the acquired data, and the alias-suppressing kernel is designed to suppress aliasing artifacts in stopbands defined by the sample spacing of the channel combination kernels.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: July 12, 2016
    Assignee: SUNNYBROOK RESEARCH INSTITUTE
    Inventor: Philip James Beatty
  • Publication number: 20160053050
    Abstract: Polyester polyols made from thermoplastic polyesters are disclosed. The polyols are reaction products of a thermoplastic polyester, a glycol, and a hydrophobe selected from ricinoleic acid, ethoxylated castor oil, saturated or unsaturated C9-C18 dicarboxylic acids, tung oil, soybean oil, sunflower oil, cardanol-based products, recycled cooking oil, isostearyl alcohol, hydroxy-functional materials derived from epoxidized, ozonized, or hydroformylated fatty esters or fatty acids, and mixtures thereof. In one process, the polyols are made by reacting the thermoplastic polyester with a glycol to give a digested intermediate, which is then reacted with the hydrophobe. In another process, the thermoplastic polyester, glycol, and hydrophobe are combined and reacted in a single step. These hydrophobes facilitate the production from recycled thermoplastics of polyols that have good transparency and little or no particulate settling or phase separation.
    Type: Application
    Filed: October 19, 2015
    Publication date: February 25, 2016
    Inventors: Rick Tabor, Kevin Anthony Rogers, Eric D Vrabel, Matthew James Beatty, Woo-Sung Bae, Shakti L Mukerjee
  • Patent number: 9239367
    Abstract: In an embodiment, a method includes processing magnetic resonance (MR) data according to a process including applying a density filter to blades of k-space data rotated about a section of k-space. Each blade may include a first set of encode lines weighted in a first signal weighting and a second set of encode lines weighted in a second signal weighting. The density filter may be configured to preferentially weight each blade in the first signal weighting to produce blades of weighted k-space data.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: January 19, 2016
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: James Hartman Holmes, Philip James Beatty
  • Publication number: 20150315325
    Abstract: The presently disclosed and/or claimed inventive concept(s) relates generally to oligomeric reaction products formed by the depolymerization of polyethylene terephthalate polymers and methods thereof. More specifically, the presently disclosed and/or claimed inventive concept(s) relates to oligomeric reaction products formed by the depolymerization of polyethylene terephthalate polymer obtained from, for example but not by way of limitation, waste products, such as beverage containers made from polyethylene terephthalate (PET). The oligomeric reaction products can, in one embodiment, be used as a starting material for polyurethanes. The presently disclosed and/or claimed inventive concept(s) also relates to processes for producing oligomeric reaction products from the depolymerization of polyethylene terephthalate.
    Type: Application
    Filed: December 17, 2013
    Publication date: November 5, 2015
    Inventors: Rick L. Tabor, Daniel James Seyer, Kristopher M Felice, Adam W. Emerson, Matthew Thomas Brown, Kyle Harris McGrath, Mickey Kellerman, Kevin Anthony Rogers, Jack Rogers Kovsky, Matthew James Beatty, Eric David Vrabel
  • Patent number: 9103898
    Abstract: A method includes the acts of acquiring a blade of k-space calibration data; acquiring a set of T1-weighted k-space imaging data, the set of T1-weighted k-space imaging data having blades of undersampled k-space data rotated about a section of k-space. Each blade of undersampled k-space data includes first data points having acquired data and second data points that are missing data. The method also includes generating a set of reconstruction weights for the blades of undersampled k-space data using the blade of k-space calibration data; synthesizing k-space data for at least a portion of the second data points using the set of reconstruction weights; and generating a T1-weighted image using the T1-weighted k-space imaging data and the synthesized k-space data.
    Type: Grant
    Filed: April 18, 2012
    Date of Patent: August 11, 2015
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: James Hartman Holmes, Jean Helen Brittain, Reed Frederick Busse, Ajeetkumar Gaddipati, Xiaoli Zhao, Philip James Beatty, Zhiqiang Li, Howard Andrew Rowley