Abstract: A microtiter plate having at least one well and a lid having at least one insert which seals and reduces the volume of the well and methods of using the combination of the well and insert are described herein.

Abstract: A method for removing a contaminant from water includes mixing droplets of a substantially non-water soluble oil with water to combine with the contaminant. The oil can include polar or ionic functional groups. A chemical destabilizer is added to the water to coagulate and aggregate the oil-contaminant mixture. The mixture is then separated from the water by gravity settling, filtration, or dissolved air flotation, thereby removing the contaminant.

Abstract: A system and method for the filtration of a solvent-particulate waste stream, such as a water solvent-particulate waste stream derived from the washing of a printing press blanket. The system and method include pumping and circulating under pressure the waste stream from a processing container through a filter to provide for a clarified solvent stream for reuse and a concentrated waste stream which is recycled back to the processing container. The system and method also include maintaining the recirculation flow rate at least than about 0.05 gallons per minute per square foot of filter surface (GFD) and removing a clarified solvent stream at a rate of less than about 2-3 gallons of flux per square foot of filter surface per day, while maintaining the pressure in the filter at a pressure of greater than about 25 psi and recycling the clarified solvent stream back for reuse in the system.

Abstract: A spirally wound ultrafiltration filter cartridge system and method which comprises a membrane sheet material forming a closed loop having a one end and an other end with first and second open spacer sheet materials, the membrane sheet material and spacer sheet material wrapped about a perforated center tube, the membrane sheet material sealed at either end by solid resin headers, the filter cartridge forming spirally wound permeate and concentrate flow channels and having a tangential, elongated feed inlet on the exterior surface of the filter cartridge. A concentrate stream is removed from the center tube and a permeate stream is removed from the one end of the closed loop of the membrane sheet material. The method of manufacture comprises spirally winding the closed end loop sheet material and the spacer sheet material about a perforated center tube and sealing either end of the membrane sheet material with a ptting resin.

Abstract: A bag filling method and apparatus for preparing pharmaceutical steril solutions in a plurality of sterile flexible bags in a non-sterile environment, which method and apparatus comprise providing a pre-sterilized tubular bag having a single inlet, introducing a solution through a sterilizing filter and introducing the sterile solution into the inlet of the tubular bag and sealing defined sections of the tubular bag after filling to a defined volume of the sterile solution to form a plurality of separate, flexible, sterile bags thereby providing a rapid, inexpensive, automated method and apparatus to prepare sterile solutions in bags.

Abstract: Water substantially free of pyrogens and microorganisms that meets the requirements of United States Pharmacopoeia Standard USP XX Water for Injection is produced by processing drinking quality water through a filtration step adapted to remove organic contaminants and impurities that degrade downstream seperation membranes, a reverse osmosis step to remove dissolved solids, pyrogens, microorganisms and chemical contamination, a deionization step to further remove dissolved solids, and an ultrafiltration step to remove pyrogens. A sterile filter to remove microorganisms increases the water quality to USP XX Sterile Water for Injection. Means are provided to periodically remove accumulated chemical contaminants, pyrogens and microorganisms from the reverse osmosis apparatus, the deionization apparatus and the ultrafiltration apparatus. The sterile water can be admixed with a sterile concentrate composition to produce a sterile dilute solution that can be packaged under sterile conditions.