Abstract: The present disclosure relates to aerosol delivery devices, methods of producing such devices, and elements of such devices. In some embodiments, the present disclosure provides devices configured for vaporization of an aerosol precursor composition that is contained in a reservoir and transported to a heating element by a liquid transport element. The liquid transport element may include a porous monolith.

Abstract: This application relates to inflatable flotation devices that support an infant, and having first, second and third inflatable members. The first member has an outer and an inner perimeter and a first and second diameters at first and second end portions. The second member is at least partially within the inner perimeter of the first member. At least a portion of the upper surface of the second member is recessed with respect to an upper surface of the first member. The third member has an inner perimeter disposed about at least a portion of the outer perimeter of the first member. The third member has a maximum height, when inflated, that is less than the maximum height of the first member, at least a portion of the inner perimeter of the third member being spaced apart from the outer perimeter of the first member.

Abstract: This application relates to inflatable flotation devices that support an infant, and having first, second and third inflatable members. The first member has an outer and an inner perimeter and a first and second diameters at first and second end portions. The second member is at least partially within the inner perimeter of the first member. At least a portion of the upper surface of the second member is recessed with respect to an upper surface of the first member. The third member has an inner perimeter disposed about at least a portion of the outer perimeter of the first member. The third member has a maximum height, when inflated, that is less than the maximum height of the first member, at least a portion of the inner perimeter of the third member being spaced apart from the outer perimeter of the first member.

Abstract: This application relates to inflatable flotation devices that support an infant, and having first, second and third inflatable members. The first member has an outer and an inner perimeter and a first and second diameters at first and second end portions. The second member is at least partially within the inner perimeter of the first member. At least a portion of the upper surface of the second member is recessed with respect to an upper surface of the first member. The third member has an inner perimeter disposed about at least a portion of the outer perimeter of the first member. The third member has a maximum height, when inflated, that is less than the maximum height of the first member, at least a portion of the inner perimeter of the third member being spaced apart from the outer perimeter of the first member.

Abstract: This application relates to flotation devices generally, and particularly to inflatable flotation devices configured for use by an infant to support the infant at least partially above the water and to at least partially retain the infant therein. In some embodiments, an apparatus is a flotation member having an inner perimeter, a top portion and a bottom portion. The flotation member has a first height between its bottom portion and its top portion at a first location of the flotation member. The flotation member has a second height between the top portion and the bottom portion at a second location of the flotation member, the second height different from the first height. The flotation member includes a support member at least partially disposed within the inner perimeter of the flotation member. The support member has a first portion coupled to the top portion of the flotation member at the first location.

Abstract: This application relates to flotation devices generally, and particularly to inflatable flotation devices configured for use by an infant to support the infant at least partially above the water and to at least partially retain the infant therein. In some embodiments, an apparatus is a flotation member having an inner perimeter, a top portion and a bottom portion. The flotation member has a first height between its bottom portion and its top portion at a first location of the flotation member. The flotation member has a second height between the top portion and the bottom portion at a second location of the flotation member, the second height different from the first height. The flotation member includes a support member at least partially disposed within the inner perimeter of the flotation member. The support member has a first portion coupled to the top portion of the flotation member at the first location.

Abstract: This application relates to flotation devices generally, and particularly to inflatable flotation devices configured for use by an infant to support the infant at least partially above the water and to at least partially retain the infant therein. In some embodiments, an apparatus is a flotation member having an inner perimeter, a top portion and a bottom portion. The flotation member has a first height between its bottom portion and its top portion at a first location of the flotation member. The flotation member has a second height between the top portion and the bottom portion at a second location of the flotation member, the second height different from the first height. The flotation member includes a support member at least partially disposed within the inner perimeter of the flotation member. The support member has a first portion coupled to the top portion of the flotation member at the first location.

Abstract: This application relates to flotation devices generally, and particularly to inflatable flotation devices configured for use by an infant to support the infant at least partially above the water and to at least partially retain the infant therein. In some embodiments, an apparatus is a flotation member having an inner perimeter, a top portion and a bottom portion. The flotation member has a first height between its bottom portion and its top portion at a first location of the flotation member. The flotation member has a second height between the top portion and the bottom portion at a second location of the flotation member, the second height different from the first height. The flotation member includes a support member at least partially disposed within the inner perimeter of the flotation member. The support member has a first portion coupled to the top portion of the flotation member at the first location.

Abstract: A system includes an electronic device coupled over a network to first and second computing devices. The electronic device is configured to serve to the first computing device a first web page displayable on a display device. The displayed first web page includes a user interface operable to solicit from an individual of a plurality of individuals a current prediction of a plurality of current predictions of market prices of a product. The electronic device is further configured to determine an accuracy rating for each individual of the plurality based on a correlation between previous predictions provided by each said individual and actual market prices of the product. The electronic device is further configured to assign to the product a price estimate associated with a first predetermined time interval, the price estimate being a function of the accuracy ratings and current predictions. The electronic device is further configured to determine a current sale price based on the assigned price estimate.

Abstract: This invention provides methods for the treatment or prevention of Alzheimer's disease in a mammal which comprises administering to a mammal in need thereof an effective amount of an inhibitor of phospholipase A.sub.2. This invention also provides a series of compounds which are useful as inhibitors of phospholipases A.sub.2, especially cytosolic phospholipase A.sub.2.

Abstract: This invention provides methods for the treatment or prevention of Alzheimer's disease in a mammal which comprises administering to a mammal in need thereof an effective amount of an inhibitor of phospholipase A.sub.2. This invention also provides a series of compounds which are useful as inhibitors of phospholipases A.sub.2, especially cytosolic phospholipase A.sub.2.

Abstract: Provided are methods of treating inflammation, arthritis and muscular dystrophy and preventing ischemia-induced cell damage employing certain phenol and benzamide compounds.

Abstract: A method for improving primary memory or learning in a mammal comprising administering a 5-hydroxytryptamine receptor agonist which is selective for the 5-hydroxytryptamine-1A receptor subtype, or a pharmaceutically acceptable salt thereof.

Abstract: Provided are methods of treating inflammation, arthritis and muscular dystrophy and preventing ischemia-induced cell damage employing certain phenol and benzamide compounds.

Abstract: Derivatives of melatonin and the pharmaceutically acceptable salts thereof are useful for therapeutically treating hormonally dependent mammalian breast carcinoma. Combination treatments of melatonin derivatives and an antiestrogen compound are especially useful.

Abstract: A method of inhibiting bone demineralization comprising administration of an effective amount of a compound having the formula ##STR1## where X is CH or N;Y is O or S;R.sup.1 is 2-propenyl, C.sub.1 -C.sub.3 alkyl, benzyl or substituted benzyl where the substitutents are one or two of the same or different and are selected from methyl, ethyl, methoxy, ethoxy, hydroxy, chloro, bromo, or fluoro;R.sup.2 is C.sub.2 -C.sub.3 alkyl, allyl or cyclopropylmethyl;R.sup.3 and R.sup.4 are both hydrogen or combine to form a carbon-carbon bond; and pharmaceutically acceptable acid addition salts thereof to a mammal requiring bone demineralization inhibition.

Abstract: Mammary cancers are inhibited by administration of a combination of two drugs. The first compound is 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-pyrrolidinoethoxy)benzoyl]benzo[b]th iophene, and the second compound is tamoxifen.

Abstract: 4-2-(di-n-propylaminoethyl)indole or a salt thereof is used to stimulate presynaptic dopamine autoreceptors in mammals.