Abstract: Systems, apparatuses, methods, and computer program products are provided for managing geographically distributed data storage in a group-based communication system and for servicing deletion requests related thereto. In some embodiments, an apparatus physically located in a first geographic area defined by a first geographic boundary is provided. In embodiments, upon determining that an entity identifier associated with a message is associated with a geographic data storage policy, the apparatus is configured to transmit a geographic data residency message package comprising message data of the message to a geographic data residency server physically located within a second geographic area defined by a second geographic boundary. The second geographic area is associated with the geographic data storage policy. In some embodiments, the apparatus is configured to update the message data of the message with residency token data received from the geographic data residency server.

Abstract: The present invention relates to aqueous alkaline abrasive cleaning compositions comprising quaternary ammonium compound that are stable over time.

Abstract: Certain configurations of an infusion device are described. In some examples, the infusion device may comprise an enclosure that can absorb radiation from a radioisotope material within the enclosure. The enclosure can also be configured to permit administration of the radioisotope material within the enclosure to a human in need of treatment for a condition such as cancer.

Abstract: The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.

Abstract: The present invention relates to a stented valve, and can be used to repair and/or replace dysfunctional heart valves. In particular, the present invention relates to a stented valve that can be used to repair and/or replace a dysfunctional mitral or tricuspid heart valve. According to the present invention, there is provided a coupling for a stented valve and a fixation element, the coupling comprising: a connector adapted to receive the fixation element, and a guide adapted to receive the stented valve; wherein the connector is reciprocally movable relative to the guide.

Abstract: This invention relates to a stabilizer (10) for a steerable drilling system, in particular for use in drilling directional boreholes for oil and gas extraction. There is provided a stabilizer (10) for a steerable drilling system having a first passageway (16) and a second passageway (18) at its outer surface, the passageways being helical and extending along the length of the stabilizer, the first and second passageways being oppositely-oriented, the first and second passageways intersecting one another, the stabilizer having a number of blades (22) between the passageways, the cross-sectional area of the first passageway being larger than the cross-sectional area of the second passageway. The asymmetric passageways enable the stabilizer designer to enhance the performance of the stabilizer during drilling and tripping.

Abstract: A computer-implemented data acquisition method includes obtaining motion data telemetrically from a wireless transmitter mounted on or inside a sporting device that is handled by athletes in an athletic event, and presenting the data to viewers of the sporting event. The data includes motion data that is captured while the sporting device is being used in the athletic event and represents motion of the sporting device captured by one or more motion sensors connected to the wireless transmitter.

Abstract: A computer-implemented method is disclosed that includes instructing a human player to perform a plurality of different actions in a determined order with a physical basketball, including actions of bouncing the physical basketball, and obtaining, with one or more electronic sensors, data that characterizes motion of the physical basketball being handled by the human player who is performing the instructed actions at a location. The method also includes communicating the data from the sensors to a console videogame system that is proximate to the location, and graphically representing, in a videogame displayed on a display device, performance by the human player, the performance being affected by the captured data, the representation of performance by the human player being compared against a standard of performance.

Abstract: The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.

Abstract: This invention relates to a stabilizer (10) for a steerable drilling system, in particular for use in drilling directional boreholes for oil and gas extraction. There is provided a stabilizer (10) for a steerable drilling system having a first passageway (16) and a second passageway (18) at its outer surface, the passageways being helical and extending along the length of the stabilizer, the first and second passageways being oppositely-oriented, the first and second passageways intersecting one another, the stabilizer having a number of blades (22) between the passageways, the cross-sectional area of the first passageway being larger than the cross-sectional area of the second passageway. The asymmetric passageways enable the stabilizer designer to enhance the performance of the stabilizer during drilling and tripping.

Abstract: An oral solid dosage form containing nanoparticles is made by (a) reducing the particle size of at least one pharmaceutically active ingredient dispersed in a solution containing fish gelatin to form a nanosuspension and (b) freeze-drying the nanosuspension of step (a) to form the oral solid dosage form.

Abstract: A computer-implemented method is disclosed that includes instructing a human player to perform a plurality of different actions in a determined order with a physical basketball, including actions of bouncing the physical basketball, and obtaining, with one or more electronic sensors, data that characterizes motion of the physical basketball being handled by the human player who is performing the instructed actions at a location. The method also includes communicating the data from the sensors to a console videogame system that is proximate to the location, and graphically representing, in a videogame displayed on a display device, performance by the human player, the performance being affected by the captured data, the representation of performance by the human player being compared against a standard of performance.

Abstract: The subject matter of this specification can be embodied in, among other things, a computer-implemented athletic performance analysis method that includes obtaining, at a computer system, first motion data reflecting motion of a sporting device during one or more drills performed by an athlete. The method also includes creating and storing action data by identifying a plurality of portions of the motion data, where each of the portions correspond to one or more actions by the athlete; comparing the action data for the athlete, with the computer system, to corresponding aggregated action data for a plurality of other athletes to determine a relative skill level for the athlete with respect to the one or more actions; and generating data for a report that reflects the relative development level of the athlete.

Abstract: A computer-implemented method is disclosed that includes instructing a human player to perform a plurality of different actions in a determined order with a physical basketball, including actions of bouncing the physical basketball, and obtaining, with one or more electronic sensors, data that characterizes motion of the physical basketball being handled by the human player who is performing the instructed actions at a location. The method also includes communicating the data from the sensors to a console videogame system that is proximate to the location, and graphically representing, in a videogame displayed on a display device, performance by the human player, the performance being affected by the captured data, the representation of performance by the human player being compared against a standard of performance.

Abstract: The subject matter of this specification can be embodied in, among other things, a computer-implemented athletic performance analysis method that includes obtaining, at a computer system, first motion data reflecting motion of a sporting device during one or more drills performed by an athlete. The method also includes creating and storing action data by identifying a plurality of portions of the motion data, where each of the portions correspond to one or more actions by the athlete; comparing the action data for the athlete, with the computer system, to corresponding aggregated action data for a plurality of other athletes to determine a relative skill level for the athlete with respect to the one or more actions; and generating data for a report that reflects the relative development level of the athlete.

Abstract: A computer-implemented data acquisition method includes obtaining motion data telemetrically from a wireless transmitter mounted on or inside a sporting device that is handled by athletes in an athletic event, and presenting the data to viewers of the sporting event. The data includes motion data that is captured while the sporting device is being used in the athletic event and represents motion of the sporting device captured by one or more motion sensors connected to the wireless transmitter.

Abstract: A computer-implemented method is disclosed that includes instructing a human player to perform a plurality of different actions in a determined order with a physical basketball, including actions of bouncing the physical basketball, and obtaining, with one or more electronic sensors, data that characterizes motion of the physical basketball being handled by the human player who is performing the instructed actions at a location. The method also includes communicating the data from the sensors to a console videogame system that is proximate to the location, and graphically representing, in a videogame displayed on a display device, performance by the human player, the performance being affected by the captured data, the representation of performance by the human player being compared against a standard of performance.

Abstract: The present invention relates to a corn plant and seed with enhanced levels of protein and amino acids. The invention also relates to DNA constructs that provide expression in transgenic corn cells of an asparagine synthetase enzyme. The DNA constructs are used in a method to produce transgenic corn plants and seeds and to select for plants and seeds with enhanced levels of protein and amino acids.