Patents by Inventor James A. Down
James A. Down has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11752742Abstract: A multi-layer film and a film package made from the film are described herein that provide resealing capabilities by utilizing a tacky layer within the multi-layer film. The multi-layer film can include an outer film portion including the embedded tacky layer and an inner film portion. An opening feature formed in the multi-layer film includes a flap configured to be manipulated by a user to create an opening through the multi-layer film. The inner film portion can include a release layer configured specifically to interact with the tacky layer to provide a desired separation peel force and resealing functionalities. The outer film portion can include an outer film layer disposed on an opposite side of the tacky layer from the release layer that is configured to permanently adhere to the tacky layer.Type: GrantFiled: July 26, 2021Date of Patent: September 12, 2023Assignee: Intercontinental Great Brands LLCInventors: Stuart Mackintosh Blyth, Matthew James Down, Christopher Holt, Ying (Lora) Liang, Paul A. Zerfas
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Publication number: 20220041357Abstract: A multi-layer film and a film package made from the film are described herein that provide resealing capabilities by utilizing a tacky layer within the multi-layer film. The multi-layer film can include an outer film portion including the embedded tacky layer and an inner film portion. An opening feature formed in the multi-layer film includes a flap configured to be manipulated by a user to create an opening through the multi-layer film. The inner film portion can include a release layer configured specifically to interact with the tacky layer to provide a desired separation peel force and resealing functionalities. The outer film portion can include an outer film layer disposed on an opposite side of the tacky layer from the release layer that is configured to permanently adhere to the tacky layer.Type: ApplicationFiled: July 26, 2021Publication date: February 10, 2022Inventors: Stuart Mackintosh Blyth, Matthew James Down, Christopher Holt, Ying (Lora) Liang, Paul A. Zerfas
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Patent number: 11123963Abstract: A multi-layer film and a film package made from the film are described herein that provide resealing capabilities by utilizing a tacky layer within the multi-layer film. The multi-layer film can include an outer film portion including the embedded tacky layer and an inner film portion. An opening feature formed in the multi-layer film includes a flap configured to be manipulated by a user to create an opening through the multi-layer film. The inner film portion can include a release layer configured specifically to interact with the tacky layer to provide a desired separation peel force and resealing functionalities. The outer film portion can include an outer film layer disposed on an opposite side of the tacky layer from the release layer that is configured to permanently adhere to the tacky layer.Type: GrantFiled: August 14, 2017Date of Patent: September 21, 2021Assignee: Intercontinental Great Brands LLCInventors: Stuart Mackintosh Blyth, Matthew James Down, Christopher Holt, Ying (Lora) Liang, Paul A. Zerfas
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Patent number: 10759582Abstract: A flexible laminate suitable for forming a package (10) having a reclosable flap (12) is provided that includes pressure sensitive adhesive (34) extending in a periphery region past a reseal margin (42) for the flap (12) and on an opposite side therefrom for joining an outer and inner layer (30, 36) of the laminate together, whether directly or indirectly. The pressure sensitive adhesive (34) can overlie a permanent adhesive (32) in the periphery region, or directly join the outer and inner layers of the laminate together. The use of pressure sensitive adhesive (34) in the region can reduce the tight registration needed for cutting the outer layer (30) to define an outward layer of the flap (12), thereby reducing the chances for cutting into a portion of the outer layer (30) joined only by permanent adhesive (32) to the inner layer (36).Type: GrantFiled: March 15, 2016Date of Patent: September 1, 2020Assignee: Kraft Foods Schweiz Holding GmbHInventor: Matthew James Down
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Publication number: 20200198309Abstract: A multi-layer film and a film package made from the film are described herein that provide resealing capabilities by utilizing a tacky layer within the multi-layer film. The multi-layer film can include an outer film portion including the embedded tacky layer and an inner film portion. An opening feature formed in the multi-layer film includes a flap configured to be manipulated by a user to create an opening through the multi-layer film. The inner film portion can include a release layer configured specifically to interact with the tacky layer to provide a desired separation peel force and resealing functionalities. The outer film portion can include an outer film layer disposed on an opposite side of the tacky layer from the release layer that is configured to permanently adhere to the tacky layer.Type: ApplicationFiled: December 20, 2019Publication date: June 25, 2020Inventors: Stuart Mackintosh Blyth, Matthew James Down, Chris Holt, Elena Jaeger, Ying (Lora) Liang
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Publication number: 20190168491Abstract: A multi-layer film and a film package made from the film are described herein that provide resealing capabilities by utilizing a tacky layer within the multi-layer film. The multi-layer film can include an outer film portion including the embedded tacky layer and an inner film portion. An opening feature formed in the multi-layer film includes a flap configured to be manipulated by a user to create an opening through the multi-layer film. The inner film portion can include a release layer configured specifically to interact with the tacky layer to provide a desired separation peel force and resealing functionalities. The outer film portion can include an outer film layer disposed on an opposite side of the tacky layer from the release layer that is configured to permanently adhere to the tacky layer.Type: ApplicationFiled: August 14, 2017Publication date: June 6, 2019Inventors: Stuart Mackintosh Blyth, Matthew James Down, Christopher Holt, Ying (Lora) Liang, Paul A. Zerfas
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Publication number: 20190047266Abstract: A multi-layer film and a film package made from the film are described herein that provide resealing capabilities by utilizing a tacky layer within the multi-layer film. The multi-layer film can include an outer film portion including the embedded tacky layer and an inner film portion. An opening feature formed in the multi-layer film includes a flap configured to be manipulated by a user to create an opening through the multi-layer film. The inner film portion can include a release layer configured specifically to interact with the tacky layer to provide a desired separation peel force and resealing functionalities. The outer film portion can include an outer film layer disposed on an opposite side of the tacky layer from the release layer that is configured to permanently adhere to the tacky layer.Type: ApplicationFiled: February 16, 2016Publication date: February 14, 2019Inventors: Stuart Mackintosh Blyth, Matthew James Down, Chris Holt, Elena Jaeger, Ying (Lora) Liang
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Publication number: 20180079575Abstract: A flexible laminate suitable for forming a package (10) having a reclosable flap (12) is provided that includes pressure sensitive adhesive (34) extending in a periphery region past a reseal margin (42) for the flap (12) and on an opposite side therefrom for joining an outer and inner layer (30, 36) of the laminate together, whether directly or indirectly. The pressure sensitive adhesive (34) can overlie a permanent adhesive (32) in the periphery region, or directly join the outer and inner layers of the laminate together. The use of pressure sensitive adhesive (34) in the region can reduce the tight registration needed for cutting the outer layer (30) to define an outward layer of the flap (12), thereby reducing the chances for cutting into a portion of the outer layer (30) joined only by permanent adhesive (32) to the inner layer (36).Type: ApplicationFiled: March 15, 2016Publication date: March 22, 2018Inventor: Matthew James Down
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Patent number: 9717451Abstract: A device includes a plurality of skin penetrating devices for delivering or withdrawing a substance through the skin of a patient. The device has a support formed with a top and bottom end and a plurality of channels extending axially through the support. A plurality of the skin penetrating members is positioned in the channels with a tip extending from the bottom end of the support. A coupling member is attached to the support for coupling with a fluid supply and directing the fluid to the skin penetrating members. The skin penetrating members have a length of about 100 microns to about 2000 microns and are about 30 to 50 gauge.Type: GrantFiled: April 10, 2012Date of Patent: August 1, 2017Assignee: Becton, Dickinson and CompanyInventors: James Down, Noel G. Harvey, Frank E. Martin, Ronald J. Pettis, Alexander G. Lastovich
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Publication number: 20160331911Abstract: Methods for ID delivery of drugs and other substances to humans or animals are provided. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. Delivery devices which place the needle outlet at an appropriate depth in the intradermal space and control the volume and rate of fluid delivery to provide accurate delivery of the substance to the desired location without leakage are also provided herein.Type: ApplicationFiled: May 16, 2016Publication date: November 17, 2016Applicant: Becton, Dickinson and CompanyInventors: Ronald J. Pettis, James A. Down, Noel J. Harvey
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Publication number: 20160207253Abstract: A device includes a plurality of skin penetrating devices for delivering or withdrawing a substance through the skin of a patient. The device has a support formed with a top and bottom end and a plurality of channels extending axially through the support. A plurality of the skin penetrating members is positioned in the channels with a tip extending from the bottom end of the support. A coupling member is attached to the support for coupling with a fluid supply and directing the fluid to the skin penetrating members. The skin penetrating members have a length of about 100 microns to about 2000 microns and are about 30 to 50 gauge.Type: ApplicationFiled: April 10, 2012Publication date: July 21, 2016Inventors: James Down, Noel G. Harvey, Frank E. Martin, Ronald J. Pettis, Alexander G. Lastovich
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Patent number: 9339613Abstract: The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient.Type: GrantFiled: March 13, 2015Date of Patent: May 17, 2016Assignee: BECTON, DICKINSON AND COMPANYInventors: Ronald J. Pettis, James A. Down, Noel J. Harvey
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Patent number: 9242052Abstract: A method for directly delivering whereby a substance is introduced into an intradermal space within mammalian skin which involves administering the substance through at least one small gauge hollow needle having an outlet with an exposed height between 0 and 1 mm. The outlet is inserted into the skin to a depth of between 0.3 mm and 2 mm such that the delivery of the substance occurs at a depth between 0.3 mm and 2 mm.Type: GrantFiled: March 17, 2014Date of Patent: January 26, 2016Assignee: Becton, Dickinson and CompanyInventors: Ronald J Pettis, Noel G Harvey, James A Down
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Publication number: 20150182705Abstract: The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient.Type: ApplicationFiled: March 13, 2015Publication date: July 2, 2015Inventors: Ronald J. Pettis, James A. Down, Noel J. Harvey
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Patent number: 9005182Abstract: The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient.Type: GrantFiled: April 19, 2013Date of Patent: April 14, 2015Assignee: Becton, Dickinson and CompanyInventors: Ronald J. Pettis, James A. Down, Noel G. Harvey
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Patent number: 8998877Abstract: The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient.Type: GrantFiled: April 19, 2013Date of Patent: April 7, 2015Assignee: Becton, Dickinson and CompanyInventors: Ronald J. Pettis, James A. Down, Noel G. Harvey
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Patent number: 8986280Abstract: The present invention provides improved methods for ID delivery of drugs and other substances to humans or animals. The methods employ small gauge needles, especially microneedles, placed in the intradermal space to deliver the substance to the intradermal space as a bolus or by infusion. It has been discovered that the placement of the needle outlet within the skin and the exposed height of the needle outlet are critical for efficacious delivery of active substances via small gauge needles to prevent leakage of the substance out of the skin and to improve absorption within the intradermal space. The pharmacokinetics of hormone drugs delivered according to the methods of the invention have been found to be very similar to the pharmacokinetics of conventional SC delivery, indicating that ID administration according to the methods of the invention is likely to produce a similar clinical result (i.e., similar efficacy) with the advantage of reduction or elimination of pain for the patient.Type: GrantFiled: April 19, 2013Date of Patent: March 24, 2015Assignee: Becton, Dickinson and CompanyInventors: Ronald J. Pettis, James A. Down, Noel G. Harvey
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Publication number: 20140200547Abstract: A method for directly delivering whereby a substance is introduced into an intradermal space within mammalian skin which involves administering the substance through at least one small gauge hollow needle having an outlet with an exposed height between 0 and 1 mm. The outlet is inserted into the skin to a depth of between 0.3 mm and 2 mm such that the delivery of the substance occurs at a depth between 0.3 mm and 2 mm.Type: ApplicationFiled: March 17, 2014Publication date: July 17, 2014Applicant: Becton Dickinson and CompanyInventors: Ronald J. Pettis, Noel G. Harvey, James A. Down
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Patent number: 8708994Abstract: A method for directly delivering whereby a substance is introduced into an intradermal space within mammalian skin which involves administering the substance through at least one small gauge hollow needle having an outlet with an exposed height between 0 and 1 mm. The outlet is inserted into the skin to a depth of between 0.3 mm and 2 mm such that the delivery of the substance occurs at a depth between 0.3 mm and 2 mm.Type: GrantFiled: March 28, 2011Date of Patent: April 29, 2014Assignee: Becton, Dickinson and CompanyInventors: Ronald J. Pettis, Noel G. Harvey, James A. Down
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Publication number: 20130263997Abstract: A device includes a plurality of skin penetrating devices for delivering or withdrawing a substance through the skin of a patient. The device has a support formed with a top and bottom end and a plurality of channels extending axially through the support. A plurality of the skin penetrating members is positioned in the channels with a tip extending from the bottom end of the support. A coupling member is attached to the support for coupling with a fluid supply and directing the fluid to the skin penetrating members. The skin penetrating members have a length of about 100 microns to about 2000 microns and are about 30 to 50 gauge.Type: ApplicationFiled: April 10, 2012Publication date: October 10, 2013Inventors: James Down, Noel G. Harvey, Frank E. Martin, Ronald J. Pettis, Alexander G. Lastovich