Abstract: The system described herein provides a method for deploying, managing, scaling, configuring, upgrading, and modifying large complicated systems that are made-up of many different network resources. These network resources may be virtual machines or containers. The system constructs a hierarchical SNS by building up layers from the inside of an outer SNS. The system conducts health checks at each layer to ensure the system is properly functioning and the deployment is healthy. Lastly, third party vendors input logic in each layer to identify a desired state for the system. Once the desired state is identified, each layer can determine the necessary actions to upgrade from the current state to the desired state. This system simplifies, adds efficiency, and increases security when deploying, scaling, configuring, upgrading, or modifying the system.

Abstract: Methods, systems, and devices are described for providing network access services to mobile users via mobile terminals over a satellite system. In embodiments, dynamic multiplexing of traffic from fixed terminals and mobile users on the same satellite beam can take advantage of statistical multiplexing of large numbers of users and on different usage patterns between fixed terminals and mobile users. In embodiments, quality-of-service (QoS) is controlled for mobile devices at a per-user level. Mobile users may be provisioned on the satellite system according to a set of traffic policies based on their service level agreement (SLA). System resources of the satellite may be allocated to mobile users based on the demand of each mobile user and the set of traffic polices associated with each mobile user, regardless of which mobile terminal is used to access the system.

Abstract: Surgical tools and assemblies are employed for use in minimally invasive surgical (MIS) procedures. A surgical tool assembly includes a handle assembly and a frame assembly. The handle assembly and frame assembly are designed and constructed to have an articulation input joint and a grounding joint between them. A pitch rotational degree of freedom and a yaw rotational degree of freedom are provided by way of the articulation input joint. The handle assembly is translationally constrained relative to the frame assembly by way of the grounding joint. Intermediate bodies and joints can be provided in certain surgical tool assemblies and architectures.

Abstract: An adjustable spinal stabilization system for maintaining preselected spacing and movement between adjacent vertebrae in a spinal column and for providing overall stability thereto. The system includes at least one interlaminar member positioned in the spaces intermediate a first vertebra and the vertebrae positioned immediately above or immediately below and adjacent to the first vertebra. The interlaminar member is operatively connected to an adjustable support structure and cooperates therewith to maintain the preselected spacing between adjacent vertebrae and to provide overall stability to the spinal column.

Abstract: A series of fused pentacyclic imidazole derivatives, being potent modulators of human TNFa activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. In particular, the present invention is concerned with 6, 7-dihydro-7, 14-methanobenzimidazo[1, 2-b][2,5]benzodiazocin-5(14H)-one derivatives and analogs thereof.

Abstract: A method of producing levoglucosenone from particulate cellulosic material. The method comprises forming a premix of particulate cellulosic material, water, acid and a polar organic solvent. The solvent has a higher boiling point than levoglucosenone. The pre-mix is fed into a pyrolysis reactor, such as a fluidised bed reactor, in which the pre-mix is fluidised by a fluidising gas. The reactor is maintained at a temperature within the range 250° C. to 450° C., and gaseous products and char are withdrawn from the pyrolysis reactor. Levoglucosenone and the polar organic solvent are condensed from the gaseous products, produced by the reactor.

Abstract: Techniques are described for generating a virtualized network function (VNF) descriptor (VNFD) indicative of resources for managing VNF components (VNFCs) across a plurality of virtualized infrastructure managers (VIMs) implemented in a virtualized computing environment configured in a user-specific configuration. A VNFD generator receives a solution description file (SDF) encoding user input pertaining to the user-specific configuration, and a VNFC descriptor encoding VNFC specific information. The SDF and VNFC descriptor are validated and translated to generate an abstracted VNFD that is independent of renderers implemented at the virtualized computing environment. The abstracted VNFD is translated to a VNFD that is specific to the renderers and VIM and VNFD-specific information at the virtualized computing environment.

Abstract: A radioactive thermogel suspension, including a thermogel and a plurality of insoluble radioactive isotope phosphate particles, such as yttrium phosphate, suspended in the thermogel. The thermogel is PLGA-g-PEG. The thermogel contains less than 65 ppm stannous octanoate. The plurality of radioactive yttrium phosphate particles are between 0.03 µm and 10 µm in diameter. The plurality of radioactive yttrium phosphate particles are generally spherical. The YPO4 particle concentration is in the range of 3 mg/ml to 100 mg/ml.

Abstract: A ballistic vest includes a carrier and at least two ballistic panels supported in the carrier, including a front ballistic panel and a back ballistic panel. The carrier is made from at least two layers of material including an outer layer and an inner layer that are joined to each other at the top and bottom of the vest and that are substantially open at the sides. The carrier has portions defining a left armhole and a right armhole. The two carrier layers define between them a panel space in the carrier. An upper part of the panel space is located above the bottom of the left and right armholes and a lower part of the panel space is located below the bottom of the left and right armholes. The front panel has an upper section that is positioned in the upper part of the panel space, the carrier substantially constraining lateral movement of the front panel upper section within the panel space.

Abstract: Techniques are described for generating a virtualized network function (VNF) descriptor (VNFD) indicative of resources for managing VNF components (VNFCs) across a plurality of virtualized infrastructure managers (VIMs) implemented in a virtualized computing environment configured in a user-specific configuration. A VNFD generator receives a solution description file (SDF) encoding user input pertaining to the user-specific configuration, and a VNFC descriptor encoding VNFC specific information. The SDF and VNFC descriptor are validated and translated to generate an abstracted VNFD that is independent of renderers implemented at the virtualized computing environment. The abstracted VNFD is translated to a VNFD that is specific to the renderers and VIM and VNFD-specific information at the virtualized computing environment.

Abstract: Techniques are described for deploying a virtualized computing environment configured in a user-specific configuration, the virtualized network function comprising a plurality of virtual machines. A solution definition file (SDF) identifies a configuration for the deployment. The SDF replaces each secret needed for the deployment with an identifier for the secret. A schema defines a format for each identifier for each secret included in the SDF and a format of the secrets. The secrets and corresponding identifiers are stored in a secure storage. The identifiers are sent to the deployed virtual machines, the identifiers being usable by the virtual machines to obtain the secrets from the secure storage.

Abstract: A system for processing cells is provided. The system can include a cell culture container, a fluid handling device, and one or more removable cell processing modules for performing one or more cell processing processes. The one or more removable cell processing modules can include a fluid handling pathway. The one or more removable cell processing modules can be fluidly connected to the cell culture container and the fluid handling device via a receptacle in which the cell processing modules may be inserted. The system can be a closed system.

Abstract: Techniques are described for generating a virtualized network function (VNF) descriptor (VNFD) indicative of resources for managing VNF components (VNFCs) across a plurality of virtualized infrastructure managers (VIMs) implemented in a virtualized computing environment configured in a user-specific configuration. A VNFD generator receives a solution description file (SDF) encoding user input pertaining to the user-specific configuration, and a VNFC descriptor encoding VNFC specific information. The SDF and VNFC descriptor are validated and translated to generate an abstracted VNFD that is independent of renderers implemented at the virtualized computing environment. The abstracted VNFD is translated to a VNFD that is specific to the renderers and VIM and VNFD-specific information at the virtualized computing environment.

Abstract: Provided is 4-methylumbelliferone, derivatives and salts thereof, or a composition comprising same for use in the treatment of a condition of the nervous system in a subject. Preferably, the condition is one associated with a scar, such as a glial scar. Typically, the condition of the nervous system is selected from the group comprising conditions caused by trauma, injury, infection, degeneration, structural defects, tumours, blood flow disruption. The neural and other lesions are made permeable and repairable.

Abstract: Techniques are described for generating a virtualized network function (VNF) descriptor (VNFD) indicative of resources for managing VNF components (VNFCs) across a plurality of virtualized infrastructure managers (VIMs) implemented in a virtualized computing environment configured in a user-specific configuration. A VNFD generator receives a solution description file (SDF) encoding user input pertaining to the user-specific configuration, and a VNFC descriptor encoding VNFC specific information. The SDF and VNFC descriptor are validated and translated to generate an abstracted VNFD that is independent of renderers implemented at the virtualized computing environment. The abstracted VNFD is translated to a VNFD that is specific to the renderers and VIM and VNFD-specific information at the virtualized computing environment.

Abstract: Many embodiments of a surgical tool are set forth herein that can be employed for use in minimally invasive surgical procedures and in remote access surgical procedures. The surgical tool has multiple bodies with one or more detachable structural interfaces that can be established between one or more pairs of the bodies. Certain locks, interlocks, and/or joints can be present in the surgical tool and among the bodies in various embodiments in order to provide certain functionalities during use.

Abstract: In an image guidance method, a stream of cone-beam computed tomography (CBCT) images of an anatomical organ is acquired using a CBCT imaging device (34). For each CBCT image (44), the surface of the organ in the CBCT image is segmented to generate a segmented surface (70) of the anatomical organ in the CBCT image. Occluded shape reconstruction (66) using a statistical shape prior (68) may be used to reconstruct a missing or occluded surface portion. A pre-operative medical image (12) of the anatomical organ and the CBCT image are spatially registered by warping one of the images to the other of the images using point set registration of a segmented surface (30) of the organ in the preoperative medical image and the segmented surface of the organ in the CBCT image. A fused image (82) is displayed that combines the warped image and the other image.

Abstract: A system, method, and apparatus are disclosed for determining ABL wind field advection speed and direction comprising collecting at least two wind volumes from the ABL wind field, defining portions of the measurement domain within the at least two wind volumes for analysis, determining the advection of an isolated wind field between the at least two wind volumes, and iterating a process of correcting for intra-volume advection, objective analysis, and determining the inter-volume advective properties; wherein upon convergence of a measured advection profile, the advective properties of the ABL wind field have been appropriately derived.

Abstract: A buoy system for treating cardiac valve regurgitation comprising a movable plug having atrial and ventricular ends, wherein a through-hole passes from the atrial to the ventricular end, wherein during systole, the plug travels toward a cardiac atrium, wherein during diastole, the plug travels into a cardiac ventricle; a tether having atrial and ventricular ends, wherein the tether passes through the through-hole of the moving plug, wherein the atrial end of the tether projects into an atrium, wherein the atrial end of the tether includes a cap to engage a delivery tool; at least one distal anchor located in the ventricle, wherein the distal anchor is coupled to the ventricular end of the tether, and wherein the system is percutaneously delivered and optionally recaptured via catheter and recapture tool at the cap of the tether, respectively.

Abstract: An adjustable spinal stabilization system for maintaining preselected spacing and movement between adjacent vertebrae in a spinal column and for providing overall stability thereto. The system includes at least one interlaminar member positioned in the spaces intermediate a first vertebra and the vertebrae positioned immediately above or immediately below and adjacent to the first vertebra. The interlaminar member is operatively connected to an adjustable support structure and cooperates therewith to maintain the preselected spacing between adjacent vertebrae and to provide overall stability to the spinal column.