Patents by Inventor James A. Ford

James A. Ford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220220457
    Abstract: The present invention concerns proteins having improved omega-transaminase (?-TA) activity, nucleic acid molecules encoding respective proteins having improved ?-TA activity and methods for stereo selective synthesis of chiral amines and amino acids or increasing of chiral amines isomers in enantiomer mixtures.
    Type: Application
    Filed: July 30, 2019
    Publication date: July 14, 2022
    Inventors: Nina BOHLKE, Wayne COCO, Mark James FORD, Saskia FUNK, Ulrike KELLER, Oliver KENSCH, Ksenia NIESEL, Nilkolaus PAWLOWSKI, Moritz SCHON, Cindy SCHULENBURG, Andreas Karl STEIB, Christina THIES
  • Publication number: 20220079942
    Abstract: The present invention relates to compounds of formula I as defined herein, and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity. The present invention also relates to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.
    Type: Application
    Filed: April 29, 2021
    Publication date: March 17, 2022
    Inventors: Emma L. Carswell, Mark David Charles, Chukuemeka Tennyson Ekwuru, Frederic Elustondo, Katherine M. Fowler, Gregory R. Ott, Jonathan R. Roffey, Joanna L. Brookfield, Daniel James Ford, Mathew L. Calder
  • Patent number: 11245567
    Abstract: Technology for operating a computer system to manage network communications with plural devices, comprising retrieving from a registry one or more device capability profiles for the identified devices, the registry linking a device capability profile with each of the identified plural devices and the device capability profile identifying one or more capabilities of a device; operating in the computer system a message translation manager to adapt a message according to a linked device capability profile of each of the plural devices; and sending the message in adapted form to each identified one of the plural devices.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: February 8, 2022
    Assignee: ARM IP LIMITED
    Inventors: Daniel Ros, Robert George Taylor, John-Paul Stanford, Daniel John Ward, Oliver James Ford
  • Publication number: 20210363106
    Abstract: The present invention primarily relates to a process for producing certain substituted 2-allylanilines of the hereinbelow-defined formula (I) and their use in a process for producing substituted 4-aminoindane derivatives of the hereinbelow-defined formula (V). The present invention further relates to a process for producing fungicidal indanyl carboxamides. In particular, the present invention relates to a process for producing 2-(difluoromethyl)-N-(1,1-dimethyl-3-propyl-2,3-dihydro-1H-inden-4-yl)nicotinamide and/or 3-(difluoromethyl)-N-[(R)-2,3-dihydro-1,1,3-trimethyl-1H-inden-4-yl]-1-methylpyrazole-4-carboxamide.
    Type: Application
    Filed: May 21, 2019
    Publication date: November 25, 2021
    Inventors: Florian ERVER, Mark James FORD
  • Publication number: 20210276958
    Abstract: The present invention relates to a process for preparing compounds of the formula (I) starting from compounds of the formula (II) in which R1, R2 and R3 have the abovementioned meaning and where R1 and R3 are not simultaneously hydrogen in any compound. The invention further provides the compounds of the formulae (IVa), (IVb), (V) and (VI) in which R1, R2, R3, R5, M and n have the abovementioned meaning.
    Type: Application
    Filed: May 20, 2019
    Publication date: September 9, 2021
    Applicant: Bayer Aktiengesellschaft
    Inventors: Andreas REMBIAK, Thomas MECHLER, Mark James FORD
  • Publication number: 20210269414
    Abstract: The present invention relates to a process for preparing compounds of the formula (I) starting from compounds of the formula (II) wherein X, R1, R2, R3, R4, U, A1, A2, A3 and A4 are defined as described above. The invention relates to compounds of the formulae (III) and (IV) wherein all variables are defined as above.
    Type: Application
    Filed: June 17, 2019
    Publication date: September 2, 2021
    Applicant: Bayer Aktiengesellschaft
    Inventors: Andreas REMBIAK, Kira HEIL, Andreas Karl STEIB, Mark James FORD
  • Patent number: 11020396
    Abstract: The present invention relates to compounds of formula I as defined herein, and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity. The present invention also relates to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: June 1, 2021
    Assignee: Cancer Research Technology Limited
    Inventors: Emma L. Carswell, Mark David Charles, Chukuemeka Tennyson Ekwuru, Frederic Elustondo, Katherine M. Fowler, Gregory R. Ott, Jonathan R. Roffey, Joanna L. Brookfield, Daniel James Ford, Mathew L. Calder
  • Patent number: 11016970
    Abstract: Trace data is received for a first execution of a first query on first tables having first data values. Second data values are generated for second tables from the trace data and without accessing the first data values. The second data values are configured to reproduce, by a second execution of a second query, the evaluation states from the first execution. Evaluation states from the first execution are reproduced without accessing the first data values by performing the second execution of the second query on the second data values. The first execution evaluates only a first subset of the first data values and the generating the second data values from the trace data generates second data values corresponding to the first subset. The second execution only evaluates ones of the second data values that correspond to data values of the first subset.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: May 25, 2021
    Assignee: International Business Machines Corporation
    Inventors: James A. Ford, Lakshman R. Sakaray, Paul-John A. To
  • Patent number: 10997376
    Abstract: A computer-implemented method of operation of a translation manager intermediating message distribution in a plurality of networked devices, comprising receiving at the translation manager a request from a networked device for registration; parsing the message by the translation manager to derive an identifier of the networked device; determining by the translation manager at least one capability of the networked device; creating a pairing of the identifier of the networked device and a profile comprising the at least one capability of the networked device; storing the pairing in a data store for use by the translation manager on request to translate a message. The storing the pairing may comprise populating a lookup table and/or operating a database.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: May 4, 2021
    Assignee: Arm IP Limited
    Inventors: Daniel Ros, Robert George Taylor, John-Paul Stanford, Daniel John Ward, Oliver James Ford
  • Publication number: 20210114990
    Abstract: The present invention relates to disubstituted 3-pyrazole carboxylates of the formula (I) and a process for their preparation wherein R1, R2, R3, R4 and n are defined as above.
    Type: Application
    Filed: June 14, 2019
    Publication date: April 22, 2021
    Inventors: Sergii PAZENOK, Anton LISHCHYNSKYI, Julia Johanna HAHN, Frank MEMMEL, Mark James FORD
  • Patent number: 10970279
    Abstract: Trace data is received that was captured for an execution of a query on first tables when execution trouble occurs during an execution of the query on the first tables. Trace data includes counts of evaluation states caused by the execution and includes identifications of portions of the query that reference variables of the first tables and that correspond with the evaluation states. Second tables are generated from the evaluation state counts and the identifications of the trace data without accessing data values of the first tables, so that the first tables are kept private. Evaluation states are reproduced from the execution of the query on the first tables by executing the query on the second tables without accessing the data values of the first tables.
    Type: Grant
    Filed: June 10, 2019
    Date of Patent: April 6, 2021
    Assignee: International Business Machines Corporation
    Inventors: James A. Ford, Lakshman R. Sakaray, Paul-John A. To
  • Patent number: 10961265
    Abstract: The present invention relates primarily to a process for preparing certain phosphorus-containing cyanohydrins of the formula (I), and also to certain phosphorus-containing cyanohydrins per se and to their use for the preparation of glufosinate and/or glufosinate salts. The present invention further relates to certain mixtures particularly suitable for preparing the phosphorus-containing cyanohydrins of the formula (I).
    Type: Grant
    Filed: July 20, 2017
    Date of Patent: March 30, 2021
    Assignee: BASF SE
    Inventors: Hans-Joachim Ressel, Kilian Tellman, Mark James Ford, Martin Littmann, Friedrich August Muehlthau, Guenter Schlegel
  • Patent number: 10941167
    Abstract: The present invention primarily relates to a process for producing certain phosphorus-containing cyanohydrin esters of formula (I) and the use thereof for producing glufosinate/glufosinate salts. The present invention further relates to a process for producing glufosinate/glufosinate salts.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: March 9, 2021
    Assignee: BASF SE
    Inventors: Hans-Joachim Ressel, Kilian Tellmann, Mark James Ford, Martin Littmann, G√ľnter Schlegel
  • Patent number: 10906893
    Abstract: The invention relates to a method for preparing methyl 4-[(4,5-dihydro-3-methoxy-4-methyl-5-oxo-1H-1,2,4-triazol-1-yl)carbonyl)sulfamoyl]-5-methylthiophene-3-carboxylate from 4-methoxycarbonyl-2-methylthiophene-3-sulfonyl chloride in the presence of an imidazole base substituted in the 1-position or in the presence of a mixture of bases comprising an imidazole base substituted in the 1-position (N-alkylimidazole).
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: February 2, 2021
    Assignees: Bayer CropScience Aktiengesellschaft, Bayer Aktiengesellschaft
    Inventors: Sergii Pazenok, Christian Funke, Friedrich August Muehlthau, Mark James Ford, Arnd Neeff, Klaus-Ulrich Schiffer
  • Patent number: 10822358
    Abstract: The present invention relates primarily to processes for preparing particular phosphorus-containing ?-aminonitriles of the formulae (Ia) and (Ib) defined hereinafter from corresponding phosphorus-containing cyanohydrin esters and to the use thereof for preparation of glufosinate or of glufosinate salts. The present invention further relates to a process for preparing glufosinate or glufosinate salts.
    Type: Grant
    Filed: June 20, 2018
    Date of Patent: November 3, 2020
    Assignee: BASF SE
    Inventors: Gunter Karig, Frank Memmel, Mark James Ford
  • Patent number: 10710972
    Abstract: The present invention relates to a method for preparing substituted 2,3-dihydro-l-benzofuran derivatives.
    Type: Grant
    Filed: August 7, 2017
    Date of Patent: July 14, 2020
    Assignee: Bayer CropScience Aktiengesellschaft
    Inventors: Daniel Gallenkamp, Mark James Ford
  • Publication number: 20200190047
    Abstract: The present invention relates to a method for preparing substituted 2,3-dihydro-1-benzofuran derivatives.
    Type: Application
    Filed: August 7, 2017
    Publication date: June 18, 2020
    Inventors: Daniel GALLENKAMP, Mark James FORD
  • Publication number: 20200157128
    Abstract: The present invention relates primarily to processes for preparing particular phosphorus-containing ?-aminonitriles of the formulae (Ia) and (Ib) defined hereinafter from corresponding phosphorus-containing cyanohydrin esters and to the use thereof for preparation of glufosinate or of glufosinate salts. The present invention further relates to a process for preparing glufosinate or glufosinate salts.
    Type: Application
    Filed: June 20, 2018
    Publication date: May 21, 2020
    Inventors: Gunter Karig, Frank Memmel, Mark James Ford
  • Patent number: 10647667
    Abstract: The present invention relates to a method for preparing 3-substituted 2-vinylphenyl sulfonates.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: May 12, 2020
    Assignee: Bayer CropScience Aktiengesellschaft
    Inventors: Daniel Gallenkamp, Mark James Ford, Dirk Brohm, Florian Erver
  • Patent number: RE48622
    Abstract: A series of pyrazolo[3,4-d]pyrimidine derivatives that are substituted at the 4-position by a diaza monocyclic, bridged bicyclic or spirocyclic moiety, are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases and malaria; and organ and cell transplant rejection.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: July 6, 2021
    Assignees: UCB Biopharma SRL, Katholieke Universiteit Leuven, K.U. Leuven R&D
    Inventors: Daniel James Ford, Richard Jeremy Franklin, Anant Ramrao Ghawalkar, Helen Tracey Horsley, Qiuya Huang, James Thomas Reuberson, Bart Vanderhoydonck