Abstract: Compounds and compositions of matter are provided that are small molecule antimicrobials. The compounds are selected from JH-144, TH-04 or TH-08 or combinations thereof. Compositions of matter are provided which in an embodiment may comprise a carrier, and in further embodiments may comprise a pharmaceutically acceptable excipient, film, biofilm or edible film. Methods of use are provided in which the composition may be administered to a subject in need thereof, and in an embodiment where the subject has a bacterial infection. Other embodiments provide the composition may be contacted with surface to eliminate or reduce bacteria.

Abstract: Compounds and compositions of matter are provided that are small molecule antimicrobials. The compounds are selected from JH-144, TH-04 or TH-08 or combinations thereof. Compositions of matter are provided which in an embodiment may comprise a carrier, and in further embodiments may comprise a pharmaceutically acceptable excipient, film, biofilm or edible film. Methods of use are provided in which the composition may be administered to a subject in need thereof, and in an embodiment where the subject has a bacterial infection. Other embodiments provide the composition may be contacted with surface to eliminate or reduce bacteria.

Abstract: A goal securement device includes a ground engagement system, a ground securement system, a goal securement system, and a goal securement monitoring system. In an embodiment, the systems work cooperatively to secure a goal to the ground and monitor the status of such securement. Embodiments of each system and embodiments of various components, aspects, or features of each system are described.

Abstract: A goal securement device includes a ground engagement system, a ground securement system, a goal securement system, and a goal securement monitoring system. In an embodiment, the systems work cooperatively to secure a goal to the ground and monitor the status of such securement. Embodiments of each system and embodiments of various components, aspects, or features of each system are described.

Abstract: Described are arylnaphthalene lactone derivatives. Also disclosed herein are methods of use of the arylnaphthalene lactone derivatives as anticancer agents.

Abstract: A goal securement device includes a ground engagement system, a ground securement system, a goal securement system, and a goal securement monitoring system. In an embodiment, the systems work cooperatively to secure a goal to the ground and monitor the status of such securement. Embodiments of each system and embodiments of various components, aspects, or features of each system are described.

Abstract: A goal securement device includes a ground engagement system, a ground securement system, a goal securement system, and a goal securement monitoring system. In an embodiment, the systems work cooperatively to secure a goal to the ground and monitor the status of such securement. Embodiments of each system and embodiments of various components, aspects, or features of each system are described.

Abstract: A goal securement device includes a ground engagement system, a ground securement system, a goal securement system, and a goal securement monitoring system. In an embodiment, the systems work cooperatively to secure a goal to the ground and monitor the status of such securement. Embodiments of each system and embodiments of various components, aspects, or features of each system are described.

Abstract: Described are arylnaphthalene lactone derivatives. Also disclosed herein are methods of use of the arylnaphthalene lactone derivatives as anticancer agents.

Abstract: A goal securement device includes a ground engagement system, a ground securement system, a goal securement system, and a goal securement monitoring system. In an embodiment, the systems work cooperatively to secure a goal to the ground and monitor the status of such securement. Embodiments of each system and embodiments of various components, aspects, or features of each system are described.

Abstract: A goal securement device includes a ground engagement system, a ground securement system, a goal securement system, and a goal securement monitoring system. In an embodiment, the systems work cooperatively to secure a goal to the ground and monitor the status of such securement. Embodiments of each system and embodiments of various components, aspects, or features of each system are described.

Abstract: In one aspect, the invention relates to substituted 2-(1H-indol-3-yl)ethanol analogs and substituted 3,3a,8,8a-tetrahydro-2H-furo[2,3-b]indole analogs, derivatives thereof, and related compounds, which are useful as inhibitors of IL-6 mediated activation of the Jak2/STAT3 pathway; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with a IL6 dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: An indicator device for visually indicating a pressure of blood inside a blood vessel includes: a body, the body comprising a duct extending in the body and having a sealed proximal end; a distal end portion adapted to be positioned inside the blood vessel and including a liquid inlet opening in fluid communication with the duct; and a window including an at least semi-transparent section configured to enable visual observation of blood entering into the duct via the inlet opening when the inlet opening is located inside the blood vessel.

Abstract: An indicator device for visually indicating a pressure of blood inside a blood vessel includes: a body, the body comprising a duct extending in the body and having a sealed proximal end; a distal end portion adapted to be positioned inside the blood vessel and including a liquid inlet opening in fluid communication with the duct; and a window including an at least semi-transparent section configured to enable visual observation of blood entering into the duct via the inlet opening when the inlet opening is located inside the blood vessel.

Abstract: A broadband linearizer for use with a power amplifier. The broadband linearizer includes a preamplifier, a postamplifier and a broadband linearizer bridge coupled between the preamplifier and postamplifier. The linearizer bridge comprises a power divider for coupling power to linear and nonlinear arms, and a power combiner for combining outputs of the linear and nonlinear arms. The linear arm includes a first equalizer and a delay line, and the nonlinear arm includes a distortion generator and an attenuator. A second equalizer is coupled between the power combiner and the postamplifier. A control circuit controls settings of the preamplifier, the broadband linearizer bridge, and the postamplifier. The control circuit outputs voltage bias and constant current signals to control operation of the broadband linearizer.

Abstract: A closure with a snap type hinge cap including a first part adapted to interengage with the open neck of the container and a second part forming a cap. An integral hinge interconnects the first part and second part. Each of the parts includes a base wall and a peripheral skirt. A pair of hinged straps are attached to the skirts and extend from the skirts on opposite side of the integral hinge. The ends of the straps are straight and lie in substantially the same plane when the first part and second part are in fully open position. Each strap is stretched along its length during opening and closing of the first part and the second part. Each strap has a portion intermediate the ends which extends out of the plane when the first part and second part are in fully open position. Each intermediate portion of each strap is thinner than the ends of said strap. Each strap is untensioned when the first part and second part are in fully open position.

Abstract: A system operating at radio frequencies in the range of 10 MHZ to 60 MHZ is provided for simultaneously determining the resistivity and dielectric constant of earth formations in the vicinity of a well bore. A transmitter coil and two longitudinally spaced receiver coils are provided in the system. Circuit means for measuring the unnormalized amplitude ratio and the relative phase shift of electromagnetic waves at the spaced receiver coils are provided. A relationship is given whereby the formation dielectric constant and resistivity may be obtained from the amplitude ratio and relative phase shift measurements.

Abstract: The invention disclosed herein includes methods and apparatus for determining true formation resistivity, flushed zone resistivity and invasion diameter of the earth formation in the vicinity of a well borehole. A radio frequency electromagnetic field in the frequency range from 800 kilohertz to 4 megahertz is generated in a borehole and the electromagnetic field is detected at a plurality of longitudinally spaced locations. Measurements of the attenuation and propagation velocity of the electromagnetic wave at the longitudinally spaced receivers may then be interpreted according to predetermined relationships in terms of the formation resistivity, flushed zone resistivity and invasion diameter surrounding the borehole.

Abstract: A dielectric well logging system includes a logging tool adapted to be passed through a borehole traversing an earth formation. The logging tool includes a transmitter which induces electric energy into the earth formation at a radio frequency. Two receivers in the logging tool spaced a predetermined distance apart provides intermediate frequency signals corresponding to the electrical energy received from the earth formation. The intermediate frequency signals are transmitted by way of a cable to the surface. Surface electronics include zero crossing detectors, each detector receives a different intermediate frequency signal from the cable and provides a detector signal whose change in amplitude is representative of the intermediate frequency signal passing through zero. A source provides clock pulses at a frequency substantially greater than the frequency of the intermediate frequency signals.