Patents by Inventor James A. Halikas

James A. Halikas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active n-acylprolydipeptides having antiamnestic, antihypoxic and anorexigenic effects
    Patent number: 5439930
    Abstract: A novel class of substances of N-acyl-prolyldipeptides, which possess psychotropic activity and particularly facilitate learning and memory are described. The N-acyl-prolyldipeptides of the invention have the formula: ##STR1## wherein R.sup.1 =(C.sub.4 -C.sub.5) alkyl, cycloalkyl, aralkyl, or aryl; R.sup.2 =H.sub.1 (C.sub.1 -C.sub.4) alkyl, carbamidoalkyl, or carbalkoxyalkyl; R.sup.3 =NH.sub.2, NH(alkyl), N(alkyl).sub.2, OH, or alkoxy; and n=0-3, preferably 0-2.
    Type: Grant
    Filed: October 14, 1992
    Date of Patent: August 8, 1995
    Assignee: Russian-American Institute for New Drug Development
    Inventors: Sergei B. Seredenin, Tatiana A. Voronina, Tatiana A. Gudasheva, Rita U. Ostrovskaya, Grigori G. Rozantsev, Alexander P. Skoldinov, Sergei S. Trophimov, James A. Halikas, Taisija L. Garibova
  • 1,2,3,4-tetrahydropyrrolo-[1,2-a]-pyrazine derivatives
    Patent number: 5378846
    Abstract: 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine derivatives having the formula (Formula I) ##STR1## and therapeutically acceptable acid addition salts thereof (Formula I.HX), wherein: R.sup.1 =hydrogen or acyl groups; and R.sup.2 =hydrogen or substituted aminomethyl groups. Said compounds and their acid addition salts have psychotropic activity, particularly anxiolytic activity.
    Type: Grant
    Filed: June 11, 1993
    Date of Patent: January 3, 1995
    Assignee: Russian-American Institute For New Drug Development
    Inventors: Sergey B. Seredenin, Tatiana A. Voronina, Arkady M. Likhosherstov, Vitaly P. Peresada, Gennady M. Molodavkin, James A. Halikas
  • Treatment for cocaine use employing valproic acid
    Patent number: 5102913
    Abstract: The craving for cocaine and use of cocaine among users may be reduced by administration of valproic acid. Cocaine-usage is effectively treated with valproic acid administration.
    Type: Grant
    Filed: July 1, 1991
    Date of Patent: April 7, 1992
    Inventor: James A. Halikas
  • Treatment for cocaine use
    Patent number: 5028611
    Abstract: The craving for cocaine and use of cocaine among users may be reduced by administration of carbamazepine. Cocaine-usage is effectively treated with the carbamazepine administration.
    Type: Grant
    Filed: June 29, 1989
    Date of Patent: July 2, 1991
    Assignee: The Regents of the University of Minnesota
    Inventor: James A. Halikas