Patents by Inventor James A. Hoffmann
James A. Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10188408Abstract: This preparation set comprises a drill guide (31) comprising a bearing surface (33) intended to bear against a glenoid cavity, a passage orifice (35) intended for the passage of a guide pin (36) implanted in the glenoid cavity, and first and second guide orifices (37, 38) each opening into the bearing surface (33) and each intended to guide a drill bit (38) capable of realizing a bone bore in the glenoid cavity, the first and second guide orifices (37, 38) being inclined with respect to the extension axis of the passage orifice (35) and converging in the direction of the bearing surface (33); and a compactor (42) comprising a compaction portion (45) having a generally trapezoidal shape and intended to be impacted against the glenoid cavity so as to form a bone housing in the glenoid cavity, the compactor (42) further including a passage hole (49) extending at least partially in the compaction portion (45) and intended for the passage of the guide pin (36) implanted in the glenoid cavity.Type: GrantFiled: October 18, 2016Date of Patent: January 29, 2019Assignees: FOURNITURES HOSPITALIERES INDUSTRIE, FH ORTHOPEDICS, DURHAM VALLEY ORTHOPEDIC CONSULTANTS LLCInventors: Guillaume Rouyer, James Hoffmann, Bruce Miller
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Publication number: 20180103967Abstract: This preparation set comprises a drill guide (31) comprising a bearing surface (33) intended to bear against a glenoid cavity, a passage orifice (35) intended for the passage of a guide pin (36) implanted in the glenoid cavity, and first and second guide orifices (37, 38) each opening into the bearing surface (33) and each intended to guide a drill bit (38) capable of realizing a bone bore in the glenoid cavity, the first and second guide orifices (37, 38) being inclined with respect to the extension axis of the passage orifice (35) and converging in the direction of the bearing surface (33); and a compactor (42) comprising a compaction portion (45) having a generally trapezoidal shape and intended to be impacted against the glenoid cavity so as to form a bone housing in the glenoid cavity, the compactor (42) further including a passage hole (49) extending at least partially in the compaction portion (45) and intended for the passage of the guide pin (36) implanted in the glenoid cavity.Type: ApplicationFiled: October 18, 2016Publication date: April 19, 2018Inventors: Guillaume ROUYER, James HOFFMANN, Bruce MILLER
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Publication number: 20100125533Abstract: A computer system is operated to allow an existing investor to keep an investment in an alternative investment fund, even though the existing investor lacks the funds to pay for the unfunded capital commitments by transferring a percentage of the obligation to fund future commitment to a prospective investor. An agreement maintains privity of contract between the existing investor and the investment vehicle (a Separate Account) comprised of a fund investment manager and an investor and is managed by a fund manager for the prospective investor. The computer system operates to execute the terms of the contract such that the existing investor receives distributions from investments in the underlying alternative investment fund after payment of amounts due to the Separate Account in preference to the existing investor.Type: ApplicationFiled: September 15, 2009Publication date: May 20, 2010Inventors: Michael James Hoffmann, Craig Adam Marmer
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Patent number: 7232879Abstract: The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.Type: GrantFiled: January 30, 2004Date of Patent: June 19, 2007Assignee: Eli Lilly and CompanyInventors: John A. Galloway, James A. Hoffmann
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Publication number: 20060241047Abstract: This invention relates to FSH or a FSH variant containing an alpha and beta subunit contained in formulations, and articles of manufacture. The invention provides advantageous new proteins and nucleic acids, multi-use pharmaceutical solutions, formulations and products of said proteins and nucleic acids where none approved for commercial use had previously existed having such extended use indications. These products are particularly useful in therapeutic regimens for increasing serum levels of FSH or a FSH variant over a period of treatment. Thus, inter alia, the invention fills the need for convenient products of FSH or from a FSH variant.Type: ApplicationFiled: July 7, 2006Publication date: October 26, 2006Inventors: James Hoffmann, Jirong Lu
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Publication number: 20060073757Abstract: A process for anodically bonding an array of spacer columns to one of the inner major faces on one of the generally planar plates of an evacuated, flat panel video display. The process includes using a generally planar plate having a plurality of spacer column attachment sites; providing electrical interconnection between all attachment sites; coating each attachment site with a patch of oxidizable material; providing an array of unattached permanent glass spacer columns, each unattached permanent spacer column being of uniform length and being positioned longitudinally perpendicular to a single plane, with the plane intersecting the midpoint of each unattached spacer column; positioning the array such that an end of one permanent spacer column is in contact with the oxidizable material patch at each attachment site; and anodically bonding the contacting end of each permanent spacer column to the oxidizable material layer.Type: ApplicationFiled: November 21, 2005Publication date: April 6, 2006Inventors: James Hoffmann, Jason Elledge
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Publication number: 20060023860Abstract: A method of detecting misrouted inter-office transport facility routes in a telecommunications system is disclosed. The method includes receiving a plurality of provisioning orders corresponding to a plurality of newly requested inter-office facility routes to be added to the telecommunications system, and comparing the plurality of newly requested inter-office facility routes to a plurality of preferred routes that have been stored in a preferred routes database to identify a first set of routes that match the preferred routes, a second set of misrouted routes where a preferred route has been defined and previously stored, but where the newly requested route does not match the preferred route, and a third set of unmatched routes where a preferred route has not been previously stored in the preferred routes database.Type: ApplicationFiled: July 29, 2004Publication date: February 2, 2006Inventors: Frederick Armanino, Tomoko Convis, Raghvendra Savoor, James Hoffmann, Jerold Osato, David Berendsen, Richard Hawthorne, Randal Biederstedt, David Curry
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Publication number: 20040127399Abstract: The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.Type: ApplicationFiled: January 30, 2004Publication date: July 1, 2004Inventors: John A. Galloway, James A. Hoffmann
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Patent number: 6703365Abstract: The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.Type: GrantFiled: April 17, 2002Date of Patent: March 9, 2004Assignee: Eli Lilly and CompanyInventors: John A. Galloway, James A. Hoffmann
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Publication number: 20020165342Abstract: The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.Type: ApplicationFiled: April 17, 2002Publication date: November 7, 2002Inventors: John A. Galloway, James A. Hoffmann
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Patent number: 6388053Abstract: The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.Type: GrantFiled: October 12, 2001Date of Patent: May 14, 2002Assignee: Eli Lilly and CompanyInventors: John A. Galloway, James A. Hoffmann
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Patent number: 6133235Abstract: The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.Type: GrantFiled: July 6, 1999Date of Patent: October 17, 2000Assignee: Eli Lilly and CompanyInventors: John A. Galloway, James A. Hoffmann
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Patent number: 6024349Abstract: A stabilizing fixture particularly suited for use with a robot end effector and holding relatively flexible components while they are cut, trimmed, or otherwise machined by the end effector. The fixture includes a chassis with wheels and a plurality of upwardly projecting posts that support an upper frame. The upper frame defines a platform for supporting, aligning, and stabilizing a flexible workpiece. The frame includes a two L-shaped brackets to support the workpiece and one or more vacuum-powered suction cups for tightly gripping and holding the workpiece against the brackets.Type: GrantFiled: May 12, 1998Date of Patent: February 15, 2000Assignee: ABB Flexible Automation, Inc.Inventors: James A. Hoffmann, Douglas L. St. Onge
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Patent number: 5977071Abstract: The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.Type: GrantFiled: September 10, 1997Date of Patent: November 2, 1999Assignee: Eli Lilly and CompanyInventors: John A. Galloway, James A. Hoffmann
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Patent number: 5851995Abstract: The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.Type: GrantFiled: August 4, 1997Date of Patent: December 22, 1998Assignee: Eli Lilly and CompanyInventors: Margret B. Basinski, Richard D. DiMarchi, David B. Flora, William F. Heath, Jr., James A. Hoffmann, Brigitte E. Schoner, James E. Shields, David L. Smiley
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Patent number: 5765975Abstract: A compliant end effector particularly suited for use with a robotic arm for accurately cutting and trimming the edges of a hot molded sheet of flexible plastic. The compliant end effector includes a mount secured to the robotic arm, an adjustment assembly pivotally attached to the mount, a guide that engages the plastic sheet near the area to be cut and trimmed, a tool for cutting and trimming the flexible sheet, and a pneumatic cylinder that biases the guide into engagement with the flexible sheet and presses the sheet against a rigid surface. The pneumatic cylinder moves the guide and tool through a range of positions as the robotic arm moves along a single path of travel down the length of the flexible sheet. The guide remains in contact with the flexible sheet despite warping or other imperfections in the stabilizing surface. The tool is fixed a predetermined distance from the guide to ensure that the plastic sheet is cut and trimmed within specific tolerances.Type: GrantFiled: September 5, 1996Date of Patent: June 16, 1998Assignee: ABB Flexible Automation, Inc.Inventors: James A. Hoffmann, Douglas L. St. Onge
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Patent number: 5719266Abstract: The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.Type: GrantFiled: March 17, 1995Date of Patent: February 17, 1998Assignee: Eli Lilly and CompanyInventors: Richard D. DiMarchi, Ronald N. Hermeling, James A. Hoffmann
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Patent number: 5705483Abstract: The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.Type: GrantFiled: March 21, 1995Date of Patent: January 6, 1998Assignee: Eli Lilly and CompanyInventors: John A. Galloway, James A. Hoffmann
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Patent number: 5698669Abstract: This invention relates to human insulin analogs (tri-arg insulins) and includes two enzymatic methods for producing tri-arg insulins. These compounds can be formulated as a soluble entity up to pH 6.1 and have prolonged hypoglycemic activity. Tri-arg insulins have the basic structure of natural human insulin plus three additional arginine residues. Two of the three additional Arg residues are located in tandem at the carboxy terminus of the insulin B-chain, and the third Arg residue is located at the amino terminus of the insulin A-chain. Tri-arg insulin analogs, having certain amino acid substitutions at the B3, B10 and A21 positions, are within the instant invention.Type: GrantFiled: June 6, 1995Date of Patent: December 16, 1997Assignee: Eli Lilly and CompanyInventors: James A. Hoffmann, Peter K. Lambooy
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Patent number: 5691309Abstract: The present invention provides anti-obesity proteins, which when administered to a patient regulate fat tissue. Accordingly, such agents allow patients to overcome their obesity handicap and live normal lives with much reduced risk for type II diabetes, cardiovascular disease and cancer.Type: GrantFiled: February 6, 1995Date of Patent: November 25, 1997Assignee: Eli Lilly and CompanyInventors: Margret B. Basinski, Richard D. DiMarchi, David B. Flora, William F. Heath, Jr., James A. Hoffmann, Brigitte E. Schoner, James E. Shields, David L. Smiley