Patents by Inventor James A. Jamison

James A. Jamison has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cyclic peptide antifungal agents
    Patent number: 6670324
    Abstract: The present invention relates to compounds of formula I: where R5 is a sugar moiety. The compounds are useful in inhibiting fungal and parasitic activity and infections.
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: December 30, 2003
    Assignee: Eli Lilly and Company
    Inventors: James A. Jamison, Michael J. Rodriguez, Venkatraghavan Vasudevan
  • Cyclic peptide antifungal agents
    Patent number: 5652213
    Abstract: Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I: ##STR1## wherein R', R", R.sup.x1, R.sup.x2, R.sup.y1 -R.sup.y4, R.sup.z1, R.sup.z2, a, b, c, d, e, R.sup.0, R.sup.1 and R.sup.2 are defined as in the specification.
    Type: Grant
    Filed: March 11, 1996
    Date of Patent: July 29, 1997
    Assignee: Eli Lilly and Company
    Inventors: James A. Jamison, Michael J. Rodriguez, Lisa M. H. LaGrandeur, William W. Turner, Mark J. Zweifel
  • Cyclic peptide antifungal Agents
    Patent number: 5646111
    Abstract: Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I: ##STR1## wherein: R' is hydrogen, methyl or NH.sub.2 C(O)CH.sub.2 --;R" and R'" are independently methyl or hydrogen;R.sup.x1, R.sup.x2, R.sup.y1, R.sup.y2, R.sup.y3, and R.sup.y4 are independently hydroxy or hydrogen;R.sub.0 is a group of the formula ##STR2## R.sub.1 is C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkoxy, phenyl, p-halo-phenyl, p-nitrophenyl, phenoxy, benzyl, p-halo-benzyl, or p-nitro-benzyl; andR.sub.2 is an acyl side chain as defined herein.
    Type: Grant
    Filed: March 7, 1996
    Date of Patent: July 8, 1997
    Assignee: Eli Lilly and Company
    Inventors: Peter S. Borromeo, James A. Jamison, Michael J. Rodriguez, William W. Turner, Venkatraghaven Vasudevan
  • Cyclic peptide antifungal agents
    Patent number: 5618787
    Abstract: Provided are pharmaceutical formulations, and methods of inhibiting fungal and parasitic activity using a compound of formula I ##STR1## wherein: R', R", R'", R.sup.x1, R.sup.x2, R.sup.y1, R.sup.y2, R.sup.y3, R.sup.y4 and R.sup.0 are as defined hereinabove; andR.sup.2 is ##STR2## R.sup.3 is ##STR3## R.sup.3a, R.sup.3b, R.sup.3c and R.sup.3d are independently hydrogen, C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.12 alkynyl, C.sub.1 -C.sub.12 alkoxy, C.sub.1 -C.sub.12 alkylthio, halo, or --O--(CH.sub.2).sub.m --[O--(CH.sub.2).sub.n ].sub.p --O--(C.sub.1 -C.sub.12 alkyl) or --O--(CH.sub.2).sub.q --X--R.sup.4 ;m is 2, 3 or 4;n is 2, 3 or 4;p is 0 or 1;q is 2, 3 or 4;X is pyrrolidino, piperidino or piperazino; andR.sup.4 is hydrogen, C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.12 cycloalkyl, benzyl or C.sub.3 -C.sub.12 cycloalkylmethyl;or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: March 8, 1996
    Date of Patent: April 8, 1997
    Assignee: Eli Lilly and Company
    Inventors: James A. Jamison, Michael J. Rodriguez