Patents by Inventor James A. Kacmar
James A. Kacmar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10688416Abstract: The present invention relates to portable filtration units including filter components mated with retentate and permeate flow channels wherein particle containing solutions are introduced into the portable filtration units and contacted with the filter components for filtration thereby producing a retentate outflow and a permeate outflow for capture of desired end product.Type: GrantFiled: June 14, 2018Date of Patent: June 23, 2020Assignee: SMARTFLOW TECHNOLOGIES, INCInventors: Marc Pugh, Todd Benson, Richard Hibbitts, James A. Kacmar, Gary Cooke, Derrick Marconi, Kim Davis, Diane K. Gates, Greg Holzer, Michael Eggers
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Publication number: 20180353879Abstract: The present invention relates to portable filtration units including filter components mated with retentate and permeate flow channels wherein particle containing solutions are introduced into the portable filtration units and contacted with the filter components for filtration thereby producing a retentate outflow and a permeate outflow for capture of desired end product.Type: ApplicationFiled: June 14, 2018Publication date: December 13, 2018Inventors: Marc PUGH, Todd BENSON, Richard HIBBITTS, James A. KACMAR, Gary COOKE, Derrick MARCONI, Kim DAVIS, Diane K. GATES, Greg HOLZER, Michael EGGERS
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Patent number: 10010814Abstract: The present invention relates to portable filtration units including filter components mated with retentate and permeate flow channels wherein particle containing solutions are introduced into the portable filtration units and contacted with the filter components for filtration thereby producing a retentate outflow and a permeate outflow for capture of desired end product.Type: GrantFiled: May 7, 2015Date of Patent: July 3, 2018Assignee: SMARTFLOW TECHNOLOGIES, INC.Inventors: Marc Pugh, Todd Benson, Richard Hibbitts, James A. Kacmar, Gary Cooke, Derrick Marconi, Kim Davis, Diane K. Gates, Greg Holzer, Michael Eggers
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Patent number: 9745333Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.Type: GrantFiled: July 31, 2014Date of Patent: August 29, 2017Assignee: SMARTFLOW TECHNOLOGIES, INC.Inventors: Henry B. Kopf, James A. Kacmar
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Patent number: 8795530Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.Type: GrantFiled: January 21, 2010Date of Patent: August 5, 2014Assignee: Smartflow Technologies, Inc.Inventors: Henry B. Kopf, James A. Kacmar
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Publication number: 20120205311Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.Type: ApplicationFiled: January 21, 2010Publication date: August 16, 2012Applicant: SMARTFLOW TECHNOLOGIES, INC.Inventors: Henry B. Kopf, James A. Kacmar
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Publication number: 20110309018Abstract: The present invention relates to methods and systems for optimization of dilution of a viscous starting material to isolate and/or concentrate the product of interest from the starting source material such that the process minimizes the volume of diluent and the total volume of the waste stream generated during the process as well as maximizing the yield of desired product. The system employs cross-flow filtration modules with sub-channels that are equidistant to the inlet and outlet of said modules and such modules are characterized by optimal channel height, optimal transmembrane pressure, etc., which are selected in order to achieve the best combination of product quality and production yield.Type: ApplicationFiled: January 21, 2010Publication date: December 22, 2011Applicant: SMARTFLOW TECHNOLOGIES, INC.Inventors: Henry B. Kopf, James A. Kacmar
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Patent number: 7901937Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.Type: GrantFiled: November 3, 2008Date of Patent: March 8, 2011Assignee: Regents of the University of MinnesotaInventors: Friedrich Srienc, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar
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Publication number: 20090081770Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.Type: ApplicationFiled: November 3, 2008Publication date: March 26, 2009Applicant: Regents of the University of MinnesotaInventors: FRIEDRICH SRIENC, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar
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Publication number: 20040214314Abstract: A continuous flow bioreactor system that includes a bioreactor, an optional post-bioreactor preparation chamber, a cell sorter, and an optional pre-bioreactor preparation chamber in a closed loop, useful for enriching a heterogeneous cell population growing in the bioreactor with an isolated subpopulation of cells.Type: ApplicationFiled: November 1, 2002Publication date: October 28, 2004Inventors: Friedrich Srienc, Abdelqader Zamamiri, Nicholas R. Abu-Absi, James A. Kacmar