Abstract: Methods and apparatus are provided for private set membership using aggregation for reduced communications. A determination is made as to whether at least one data element of a client is in a data set of a server by: obtaining a transformation of the at least one data element; receiving a response from the server based on the transformation of the at least one data element, wherein the transformation comprises one or more of a Bloom filter-based transformation that employs a Bloom filter comprising a plurality of hash functions and an encryption-based transformation; and determining whether the at least one data element is in the data set based on the response, wherein one or more of the response and the determining is based on a result of at least one aggregation of a plurality of values that depend on the at least one data element and one or more items in the data set.

Abstract: The invention provides novel compounds that may serve as anticancer therapeutics. The compounds of the invention bind to polo-like kinases through the polo-box domain. In certain embodiments, the compounds of the invention are POM-protected peptide derivatives. The use of cationic bis-alkyl his residues in combination with a mono POM-protected phophoryl group results in a peptide possessing an overall neutral charge. The peptide derivatives of the invention have achieved both good efficacy and an enhanced bioavailability. The invention also provides methods of use, compositions, and kits thereof. Further, the invention provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.

Abstract: The invention provides novel compounds that may serve as anticancer therapeutics. The compounds of the invention bind to polo-like kinases through the polo-box domain. In certain embodiments, the compounds of the invention are POM-protected peptide derivatives. The use of cationic bis-alkyl his residues in combination with a mono POM-protected pho-phoryl group results in a peptide possessing an overall neutral charge. The peptide derivatives of the invention have achieved both good efficacy and an enhanced bioavailability. The invention also provides methods of use, compositions, and kits thereof. Further, the invention provides a novel method of design and/or synthesis of phosphoryl-derived peptide derivatives useful as therapeutic agents.

Abstract: A system and method for dispensing a sealant over aircraft fasteners secured to a surface in the aircraft. The system includes a nozzle tip having a shroud configured for placement over the fasteners. Sealant is metered to the shroud via an orifice within the nozzle tip. The shroud is sized to leave a space between it and the fastener to control the amount of sealant applied to the fastener upper surface and along the interface between the fastener and aircraft surface. Pressurized fluid urges the sealant through the orifice.

Abstract: A temporary fastener and a method of attaching an aircraft skin to a frame using the temporary fastener during a step of the skin to frame assembly process. The fastener secures the skin to the structure while holes for permanent fasteners are drilled through the skin and frame; the fastener is flush mounted so that an automatic drill can drill the holes without interference. The temporary fastener can be removed after the permanent fastener holes are drilled, and before or after permanent fasteners are inserted within their respective holes.

Abstract: A scanning system for scanning a wire to determine the characters provided on the wire.

Abstract: A scanning system for scanning a wire to determine the characters provided on the wire.

Abstract: A system and method for dispensing a sealant over aircraft fasteners secured to a surface in the aircraft. The system includes a nozzle tip having a shroud configured for placement over the fasteners. Sealant is metered to the shroud via an orifice within the nozzle tip. The shroud is sized to leave a space between it and the fastener to control the amount of sealant applied to the fastener upper surface and along the interface between the fastener and aircraft surface. Pressurized fluid urges the sealant through the orifice.

Abstract: A temporary fastener and a method of attaching an aircraft skin to a frame using the temporary fastener during a step of the skin to frame assembly process. The fastener secures the skin to the structure while holes for permanent fasteners are drilled through the skin and frame; the fastener is flush mounted so that an automatic drill can drill the holes without interference. The temporary fastener can be removed after the permanent fastener holes are drilled, and before or after permanent fasteners are inserted within their respective holes.

Abstract: A scanning system for scanning a wire to determine the characters provided on the wire.

Abstract: A scanning system for scanning a wire to determine the characters provided on the wire.

Abstract: A system for assembling wire harnesses with their connectors utilizes a compact computer-based system that is linked to an engineering data base. The data base contains component information, such as harness number, associated wires, and pin location to connector. An integrated tool contains a light panel that is linked to a dummy connector. The dummy connector has a mating end for the connector being pinned. The connector is mated to the dummy connector such that pin holes in the connector align with the light rods in the dummy connector. The wires are identified by voice recognition, bar code, and/or optical character recognition. Once a wire has been identified, the system illuminates the appropriate pin location on the selected connector, thereby providing a visible point of light in which the selected wire is to be terminated.

Abstract: Methods of treating a human infected with human immunodeficiency virus (HIV), such as a human with AIDS, with the purina nucleotides 2',3'-dideoxy-2'-beta-fluoroadenosine (FddA) and 2',3'-dideoxy-2'-beta-fluoroinosine (FddI) are disclosed. These nucleotides are stable in an acid environment and thus can be used for oral administration. Methods of inhibiting human immunodeficiency virus replication in a human T cell using these purina nucleotides are also disclosed.

Abstract: Purine nucleosides active against human immunodeficiency virus which are substituted at the 2'-position by a strong electronegative group such as fluorine are stable in an acid environment and thus can be used for oral administration.

Abstract: The present invention relates, in general, to prodrugs. In particular, the present invention relates to lipophilic, aminohydrolase-activated, anti-viral nucleoside prodrug compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds.

Abstract: An automatic ball return for practicing golf putting includes a ramp that receives the putted ball, converts the energy of the rolling ball into vertical movement up the ramp, and then through gravity, rolls the ball back down the ramp towards the user. Two legs attached to the ramp are interlocked when the device is in use to provide the proper contour to the ramp, and disengage so the legs and ramp lie flat when the device is to be stored or transported. The ramp includes a target on each end, and the device may be positioned with either leg along the ground allowing either target to be used.

Abstract: 5-substituted 2',3'-dideoxycytidine compounds and their monophosphates are disclosed which have been found to have potent activity against retroviruses. The 5-fluoro-and 5-aza-substituted 2',3'-dideoycytidine compounds have been found to be effective against HTLV-III/LAV virus.