Patents by Inventor James A. Lautenberger

James A. Lautenberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Productive of human T-cell leukemia (lymphotropic) retrovirus (HTLV-1) envelope protein fragments in bacteria and use in seroepidemiological studies
    Patent number: 5674705
    Abstract: Antigenic proteins may be expressed in bacteria by use of vectors having inserted therein DNA fragments from an envelope gene. The DNA fragments employed in the example are coding sequences found in the HTLV-I envelope gene. The bacteria used was E. coli. The antigenic proteins are useful in identifying antibodies to the organisms from which the DNA fragments were originally obtained.
    Type: Grant
    Filed: February 14, 1994
    Date of Patent: October 7, 1997
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Takis S. Papas, Kenneth Samuel, James A. Lautenberger, Flossie Wong-Staal
  • Production of human T-cell leukemia (lymphotropic) retrovirus (HTLV-I) envelope protein fragments in bacteria and use in seroepidemiological studies
    Patent number: 5510238
    Abstract: Antigenic proteins may be expressed in bacteria by use of vectors having inserted therein DNA fragments from an envelope gene. The DNA fragments employed in the example are coding sequences found in the HTLV-I envelope gene. The bacteria used was E. coli. The antigenic proteins are useful in identifying antibodies to the organisms from which the DNA fragments were originally obtained.
    Type: Grant
    Filed: February 7, 1994
    Date of Patent: April 23, 1996
    Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services
    Inventors: Takis S. Papas, Kenneth Samuel, James A. Lautenberger, Flossie Wong-Staal
  • Plasmid pJL6
    Patent number: 5236828
    Abstract: The plasmid of this invention contains the cII translation initiation site and a P.sub.L promoter--both are very efficient, producing large amounts of cII protein. This plasmid contains a unique ClaI restriction site in the aminoterminal portion of the cII gene suitable for insertion of foreign genes. This plasmid is an improvement over other plasmids because the inserted genes are subject to the same transcriptional and translational characteristics of the cII gene; this plasmid, therefore, produces large amounts of the protein coded by the exogenous gene.
    Type: Grant
    Filed: January 30, 1992
    Date of Patent: August 17, 1993
    Inventors: Takis S. Papas, James A. Lautenberger