Abstract: The subject matter disclosed herein relates to compositions and methods of making and using the compositions. In a further aspect, the subject matter disclosed herein relates to inhibitors of STAT3 dimerization. Methods of making these compositions as well as compositions comprising these compositions are also disclosed. Also disclosed are methods of treating or preventing certain cancers by administering to an individual in need thereof and effective amount of the compounds disclosed herein. Still further, disclosed herein are methods of inhibiting STAT3 by contacting a cell with a compound or composition as disclosed herein.

Abstract: A hydrodynamic bearing in the form of a flex pad bearing includes configurations structured to change a bearing characteristic. One form of the bearing includes a nonlinear back wall that includes a circular arc and a transition, where the back wall extends radially outward of a ligament. The bearing can include an opening for the deposit of a weighted mass, wherein the opening can threadingly receive a threaded weighted mass. In one form a sidewall that includes the back wall segment can have an average outer radius which determines a thickness of the flex pads.

Abstract: A data recovery device configured to store data onboard a hypersonic vehicle travelling at hypersonic speeds. The data recovery device is released from the hypersonic vehicle upon a release command or an anomalous event. Upon release, the data recovery device is configured to receive Global Positioning System (GPS) position data and configured to broadcast the GPS position data in short bursts during decent to a surface of the Earth and upon impact with the surface of the Earth to aid in recovery of the data recovery device.

Abstract: An actuator for use with an external controller, either alone or in a group including other actuators controlled from the same external controller. The actuator includes a housing for encasing internal components of the device; a motor assembly for creating motion, the motor assembly being disposed within the housing; and a drive assembly for driving a pushrod, the drive assembly being arranged within the housing and slidingly connected to the motor assembly. A remote control communication circuit is electrically connected to the motor. The remote control communication circuit includes a short range transmitter/receiver for paring the actuator to an external control device and a longer range transmitter/receiver for communicating operational control signals between the external control device and the actuator.

Abstract: A battery pack mounting system includes, among other things, a bracket having a first connection flange configured to connect to a vehicle structure, a second connection flange configured to connect to a battery pack, and a spanner portion spanning from the first connection flange to the second connection flange. The bracket includes one or more openings that segment the bracket into at least a first section and a second section. Each of the openings extends into both the spanner portion and the first connection flange.

Abstract: A battery pack device includes a conduit compressing against a battery cell array. The conduit is to communicate fluid that is vented from an interior of a battery cell within the battery cell array along a non-linear vent path. The conduit can include an inlet that opens to a vent chamber of the battery cell array. The conduit can be a plate. A foot could extend from the conduit. The non-linear vent path could be a first vent path, and the foot could provide a portion of a second vent path.

Abstract: A sealing system includes an exterior plate, an interior plate, a first seal received against the exterior plate and configured to restrict moisture ingress through the exterior plate, and a second seal received against the interior plate and configured to restrict moisture ingress through the interior plate. The sealing system may be used to seal around tubing that extends through a vehicle battery enclosure.

Abstract: A central claims adjuster control unit associated with an entity may oversee the assignment of claims cases to claims adjusters. The control unit may designate that a threshold number of cases may be assigned to certain claims adjusters. When new claims cases arrive, the control unit may monitor the workload of each of the claims adjusters and the threshold value assigned to any of the claims adjusters before assigning the case to one of the adjusters. If no adjuster is available, the control unit may store the case(s) in a memory until one of the adjusters becomes available. An additional feature of the control unit includes a user interface for modifying information about claims adjusters, including whether or not a threshold value is associated with them, the value of any associated threshold, and the reassignment of cases from one adjuster to another.

Abstract: Embodiments of a system and method for dynamically selecting a communication technology based at least in part on the success in forming a peer-to-peer connection for playing an instance of a video game are disclosed. Further, the systems may dynamically select a communication technology based on the quality of service of an established communication connection between two or more computing systems corresponding to two or more users attempting to play the instance of the video game. In some embodiments, the identification of a communication technology may occur during a gaming session and the communication technology used at the start of the game play session may be transitioned to another communication technology enabling the maintenance of a level of quality of service.

Abstract: The subject matter disclosed herein relates to compositions and methods of making and using the compositions. In a further aspect, the subject matter disclosed herein relates to inhibitors of STAT3 dimerization. Methods of making these compositions as well as compositions comprising these compositions are also disclosed. Also disclosed are methods of treating or preventing certain cancers by administering to an individual in need thereof and effective amount of the compounds disclosed herein. Still further, disclosed herein are methods of inhibiting STAT3 by contacting a cell with a compound or composition as disclosed herein.

Abstract: A data recovery device configured to store data onboard a hypersonic vehicle travelling at hypersonic speeds. The data recovery device is released from the hypersonic vehicle upon a release command or an anomalous event. Upon release, the data recovery device is configured to receive Global Positioning System (GPS) position data and configured to broadcast the GPS position data in short bursts during decent to a surface of the Earth and upon impact with the surface of the Earth to aid in recovery of the data recovery device.

Abstract: A rotor shaft for a high speed motor that has a coating that is secured to a shaft body. The coating and the shaft body are formed from dissimilar materials. More specifically, the coating may be an alloy material, such as, for example, a copper alloy, while the shaft body may be a steel material. According to certain embodiments, the alloy material of the coating may be secured to at least a portion of a rotor body blank in a solution treated condition via a low temperature welding procedure. Additionally, the coating may be hardened, such as for example, through the use of an age hardening process. The coating and the rotor body blank may be machined together to form the rotor shaft. According to certain embodiments, such machining may configure the rotor shaft for use with a turbo-compressor that is configured for air compression.

Abstract: For track vehicles having drive assemblies that are susceptible to buildup of mud and debris that can result in damage to the track and drive assembly, clearing members are provided that clear buildup while avoiding contact with components of the track vehicle as the track frame oscillates.

Abstract: A method determines a total velocity average cross-section parameter ?tot? in a relationship of the form ?loss(U)=nb?tot?·ƒ(U, Ud), where: ?loss(U) is a rate of exponential loss of sensor atoms from a cold atom sensor trap of trap depth potential energy U in a vacuum environment due to collisions with residual particles in the vacuum environment; nb is a number density of residual particles in the vacuum environment; Ud is a parameter given by U d = 2 ? k B ? T / m bg ? 4 ? ? ? ? ? 2 m t ? ? ? tot ? v ? which relates the masses of the sensor atoms mt and residual particles mbg to the total velocity average cross-section parameter ?tot?; and ƒ(U, Ud) is a function of the trap depth potential energy U and the parameter Ud which models a naturally occurring dependence of the loss rate ?loss(U) on the trap depth potential energy U and the parameter Ud, where ƒ(U=0, Ud) is unity for all Ud.

Abstract: An exemplary fin-tube construction includes an outer tube, an inner tube disposed within the outer tube, and a plurality of fins extending from an outer surface of the inner tube to an inner surface of the outer tube. The outer tube includes an inner portion and an outer portion. The inner portion, the inner tube, and the fins are formed at least primarily of a first material. The outer portion is formed at least primarily of a second material.

Abstract: The subject matter disclosed herein relates to compositions and methods of making and using the compositions. In a further aspect, the subject matter disclosed herein relates to inhibitors of STAT3 dimerization. Methods of making these compositions as well as compositions comprising these compositions are also disclosed. Also disclosed are methods of treating or preventing certain cancers by administering to an individual in need thereof and effective amount of the compounds disclosed herein. Still further, disclosed herein are methods of inhibiting STAT3 by contacting a cell with a compound or composition as disclosed herein.

Abstract: An assembly according to an exemplary aspect of the present disclosure includes, among other things, a top plate piece, a bottom plate piece and tubing sandwiched between the top plate piece and the bottom plate piece.

Abstract: An air outlet for controlling airflow in a vehicle includes a housing having an air inlet and an air outlet, with first and second walls between the air inlet and the air outlet wherein the first wall is spaced from the second wall, an airfoil located within the housing, and a handle moveably mounted to the airfoil by a coupling.

Abstract: Some embodiments are directed to a protective frame assembly. The frame assembly includes a first frame including an inner wall surface and an outer wall surface opposite to the inner wall surface. The inner wall surface includes a channel. The frame assembly also includes a second frame including a front wall surface and a rear wall surface. The rear wall surface of the second frame faces the inner wall surface of the first frame. The frame assembly further includes a spline received within the channel of the first frame. The frame assembly also includes a mesh sandwiched between the inner wall surface and the rear wall surface. The spline engages with the mesh within the channel to retain the mesh in a tensioned state.

Abstract: A rotor shaft for a high speed motor that has a coating that is secured to a shaft body. The coating and the shaft body are formed from dissimilar materials. More specifically, the coating may be an alloy material, such as, for example, a copper alloy, while the shaft body may be a steel material. According to certain embodiments, the alloy material of the coating may be secured to at least a portion of a rotor body blank in a solution treated condition via a low temperature welding procedure. Additionally, the coating may be hardened, such as for example, through the use of an age hardening process. The coating and the rotor body blank may be machined together to form the rotor shaft. According to certain embodiments, such machining may configure the rotor shaft for use with a turbo-compressor that is configured for air compression.