Abstract: Disclosed herein are system, method, and computer program product embodiments for generating a list of deny policy statements associated with an allow policy statement with respect to the effective access permissions for a principal in an identity and access management system. The operations can include identifying a first policy statement that specifies members of a first identity set including the principal are allowed to access a first system resource set. The operations further include identifying a second policy statement specifying that members of a second identity set are denied access to a second system resource set. Moreover, the operations include determining that the second policy statement overlaps with the first policy statement with respect to the effective access permissions for the principal, and placing the second policy statement into the list of deny policy statements associated with an allow policy statement.

Abstract: This application describes a surgical retractor and related methods for providing access to a surgical target site for the purpose performing minimally invasive spinal fusion across one or more segments of the spinal column.

Abstract: Genetically modified microorganisms that have the ability to convert carbon substrates into chemical products such as 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester are disclosed. For example, genetically modified methanotrophs that are capable of generating 2,3-BDO; 1,4-BDO; isobutyraldehyde; isobutanol; 1-butanol; n-butanol; ethanol; fatty alcohols; and fatty acid methyl ester at high titers from a methane source are disclosed. Methods of making these genetically modified microorganisms and methods of using them are also disclosed. These microorganisms and methods make use of molecular switches to regulate gene expression.

Abstract: A surgical system may include a conductive stylet with a distal end advanceable into bone material and a proximal end coupled to a stylet hub. A handle is non-removably attached to the stylet hub, and removably attachable to an insulative cannula hub. The cannula hub is non-removably attached to a conductive cannula that surrounds the stylet when the handle is attached to the proximal end of the insulative cannula hub. An outer insulative sheath is slideably engaged to insulative cannula hub, and has a radio-opaque distal tip. An electrical signal source may be applied to the stylet hub to conduct a pedicle integrity assessment. The handle and stylet may be removed from the cannula assembly, leaving the cannula assembly in place at the surgical site.

Abstract: Methods, systems, and devices for pellet-fed pizza oven are described. In some examples, a pizza oven may include a hopper for storing a combustible fuel, such as wood pellets. The wood pellets may be transferred to a burn pot by an auger. The rate at which the auger transfers the wood pellets may be managed by a controller and may be adjusted based on an ambient temperature of the oven and a desired temperature for cooking a food item (e.g., a pizza). In some instances, the pizza oven may include a cooking surface, such as a pizza stone or a pizza steel, for cooking the pizza at a desired temperature.

Abstract: A surgical simulator comprising a haptic arm capable of simulating forces generated during surgery from interactions between a surgical tool and tissue operated upon. The simulator further comprises a visual display capable of depicting a three-dimensional image of the simulated surgical tool and a physics-based computer model of the tissue. The haptic arm controls the movement and orientation of the simulated tool in the three-dimensional image, and provides haptic feedback forces to simulate forces experienced during surgery. Methods for simulating surgery and training users of the simulator are also described.

Abstract: An embodiment of a perforating gun system deployable in a wellbore extending through a subterranean earthen formation includes a tandem sub including a sub housing and a signal pod receivable in the sub housing, wherein the signal pod includes a detonator and a receptacle; and a perforating gun including a charge carrier configured to receive one or more shaped charges, the charge carrier including a detonator cord housing configured to receive a terminal end of a detonator cord, and wherein the detonator cord housing is receivable in the receptacle of the signal pod to ballistically couple the detonator cord with the detonator.

Abstract: Methods and structures are disclosed to dispense a liquefied gas solution from a liquefied gas solution (LGE) container. The LGE container comprises a temperature sensor to detect the temperature of the liquefied gas solution within the LGE container. The LGE container temperature is controlled using a temperature control element, and a processor connected to the temperature sensor and the temperature control element. The LGE is transferred from the container to a secondary container through a valve. The method includes the following steps: (a) opening the valve to allow the LGE to flow from the LGE container into the secondary container; (b) taking readings from the temperature sensor; (c) based on the temperature readings, heating the LGE container to maintain the temperature of the LGE container at a predetermined temperature or temperature range.

Abstract: A hand-held lighting device is disclosed with a handle and a head housing a first and second light source, wherein a longitudinal axis of the head is disposed at a non-parallel angle with respect to a longitudinal axis of the handle. The first light source is annular light emitting diode and the second light source is a light excited phosphor.

Abstract: Techniques for detecting and remediating a low gas pressure situation within a gas delivery system are described. In one example, a smart gas metering device measures gas pressure. The first device determines that the gas pressure value is less than a first threshold value, indicating a low gas pressure condition. The first smart metering device reports this condition to a second smart metering device, which may be nearby. In response, the first smart metering device receives gas pressure information from the second smart gas metering device. The first smart gas metering device then reports one of two conditions to a headend device, such as a main office server. In a first possibility, the report indicates a low gas pressure event confined to the first device. Alternatively, the report indicates a low gas pressure event within a distribution area comprising the first device and the second device.

Abstract: The present invention discloses a method of detecting the presence of mutated genes, mRNAs or microRNAs in a subject. The method comprises the following steps: (1) Provide a body fluid sample containing cells, circulating tumor cells (CTCs), and/or extracellular vesicles (EVs); and use an analyzer having overhang molecular beacons to measure fluorescence signals generated by interactions between the body fluid sample and the overhang molecular beacons, so as to detect the presence of the mutated genes, mRNAs or microRNA. Furthermore, a biochip comprising a gold coating substrate and tethered lipoplex nanoparticles encapsulating the overhang molecular beacons is also provided in the invention.

Abstract: An example welding-type system includes: a welding-type power source configured to provide welding-type current to a welding-type circuit, the welding-type circuit comprising a welding-type electrode and a first contact tip of a welding torch; an electrode preheating circuit configured to provide preheating current through a first portion of the welding-type electrode via a second contact tip of the welding torch; a switching circuit configured to control a current flow between the welding-type power source and the first contact tip; and a preheat control circuit configured to control the switching circuit to: selectively direct current from the welding-type power source to the second contact tip; and selectively divert current from the electrode preheating circuit to the first contact tip.

Abstract: This disclosure relates generally to surgical retractors and surgical retractor systems configured to provide access to a surgical site, such as a portion of a patient's spine. Also disclosed are retractor blades or blade assemblies connectable to surgical retractors. A self-adjusting retractor blade includes a sheath extending from a proximal end to a distal end, with the sheath having an engagement portion at the proximal end configured for releasable engagement with a surgical retractor system, a channel extending to the distal end, and a blade tip at least partially contained within the channel, the blade tip configured to slide within the channel. The blade tip may be biased in a first position relative to the sheath. Methods of assembling and using the surgical retractors and surgical systems are also disclosed.

Abstract: A cooktop appliance having a controller in operative communication with an energy control device and a pan surface temperature sensor, the controller configured to receive a pan target temperature input, receive a temperature signal corresponding to the temperature of a surface of the pan, and determine an amount of energy required to maintain a surface of the pan at the pan target temperature.

Abstract: Systems and methods for cleaning a wire electrode after a welding process has ended are described. During a welding process, a wire electrode may be fed forward from a wire feeder through a welding torch to create a molten weld pool. While, conventionally, feeding of the wire electrode stops when the welding process ends, the present disclosure contemplates instead continuing to feed the wire electrode forward after the welding process ends. More particularly, the present disclosure contemplates feeding the wire electrode into the weld pool so that the wire electrode can be “cleaned” in the molten weld pool created by the welding process. The “cleaned” wire electrode end can be more easily used to establish an electrical arc at the beginning of the next welding process.

Abstract: The present invention is related to a method and pharmaceutical composition for treating a cartilage damage in a subject (including a human or an animal), particularly osteoarthritis (OA), using extracellular vesicles (EVs) with SOX9 gene, called as “EV-SOX9”. The EV-SOX9 is obtained by encapsulating the SOX9 mRNA or the mRNA of its upstream and downstream gene in EVs, naïve EVs with high expression level of SOX9 mRNA or its upstream and downstream gene from different cell sources, or MSC-derived EV-SOX9, which is obtained by transferring the SOX9 gene or its upstream and downstream gene into a multipotent cell and collecting EVs.

Abstract: An electronic device receives a single instruction to apply a neural network operation to a set of M-bit elements stored in one or more input vector registers to initiate a sequence of computational operations related to a neural network. In response to the single instruction, the electronic device implements the neural network operation on the set of M-bit elements to generate a set of P-bit elements by obtaining the set of M-bit elements from the one or more input vector registers, quantizing each of the set of M-bit elements from M bits to P bits, and packing the set of P-bit elements into an output vector register. P is smaller than M. In some embodiments, the neural network operation is a quantization operation including at least a multiplication with a quantization factor and an addition with a zero point.

Abstract: Systems and apparatuses include a cab floor defining a center plane, a seat slide actuator coupled to the cab floor and selectively moveable in a direction transverse to the center plane relative to the cab floor, and a seat supported by the seat slide actuator and moveable therewith.

Abstract: Improved multi-layer machine learning model architectures are provided that exhibit increased accuracy, decreased training time, decreased inference compute cost, and/or increased stability while training. These improved models include a plurality of sequential layers, each layer comprising a mixing layer that feeds into a feedforward layer. These improved models achieve these benefits by ‘enhancing’ a subset of the feedforward layers with mixture-of-experts or other sparse multi-network architectures while ‘degrading’ a subset of the mixing layers to be simple linear mixing layers (e.g., that multiply inputs by one or more mixing matrices) rather than more complicated attentional mixing mechanisms (e.g., including a number of matrix multiplications, dot products, and nonlinear operations).

Abstract: An oven appliance may include a cabinet, a heat source, a temperature sensor, a user interface, and a controller. The cabinet may define a cooking chamber. The heat source may be disposed within the cooking chamber. The controller may be configured to direct a monitoring operation. The monitoring operation may include measuring a first temperature of a food item within the cooking chamber of the oven appliance, determining elapse of a detection interval instance, measuring a second temperature of the food item, calculating a temperature delta between the second temperature and the first temperature, determining the temperature delta is within a predetermined functional range, determining a time delta of time, estimating a remaining time of the food item based on the time delta in response to determining the temperature delta is within the predetermined functional range, and presenting the estimated remaining time at the user interface of the oven appliance.