Abstract: Some embodiments of a smokeless tobacco system include a container including a plurality of preformed smokeless tobacco products configured to generally retain their shape and integrity during processing, shipping, and consumer handling. One or more of the preformed smokeless tobacco products are compressed between a lid and a base of the container to hinder movement of the one or more preformed smokeless tobacco products within the container. Each preformed smokeless tobacco product can include a moist smokeless tobacco in combination with a selected binder such that the final product is configured to have material properties providing improved handling, an improved mouth feel, and a satisfying flavor profile.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts, solvates, hydrates, tautomers or stereoisomers thereof, wherein R1, R2, R2a, R3, Ra2, Ra4, Ra5, Ra6, Ra7, X1, X1a, A1 and A2 have the meaning as indicated in the description and claims. The invention further relates to pharmaceutical compositions comprising said compounds, their use as medicament and in a method for treating and preventing of one or more diseases or disorders associated with integrated stress response.

Abstract: A method disclosed herein includes displaying information associated with a first application in a display area of an electronic device, detecting a change in direction of a continuous gesture across at least a portion of the display area between a first direction and a second direction different than the first direction, the continuous gesture associated with a request to display information of a second application, the first application being different than the second application, in response to detecting the change in direction of the continuous gesture, reducing display of the first application to a first portion of the display area and presenting a preview of information associated with the second application in a second portion of the display area in which the first application was presented prior to detection of the continuous gesture, based on a first characteristic of the continuous gesture, discontinuing providing the first information and display the second application in the display area, and base

Abstract: Some embodiments of a smokeless tobacco system include a container including a plurality of preformed smokeless tobacco products configured to generally retain their shape and integrity during processing, shipping, and consumer handling. One or more of the preformed smokeless tobacco products are compressed between a lid and a base of the container to hinder movement of the one or more preformed smokeless tobacco products within the container. Each preformed smokeless tobacco product can include a moist smokeless tobacco in combination with a selected binder such that the final product is configured to have material properties providing improved handling, an improved mouth feel, and a satisfying flavor profile.

Abstract: The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

Abstract: A post for a fit together panel comprising at least one said post and at least one slat, the post comprising a base member and a cover member, the cover member comprising a pair of sidewalls and an interconnecting end wall, the interconnecting end wall containing a plurality of openings through which the end of a slat can pass, the sidewalls adapted for extension over the channel member, the base member comprising a base wall and opposed sidewalls, at least one sidewall comprising a clamping leg adapted for clamping engagement against the end of a said slat passing through a said opening in the cover member, and snap fitting means on the channel member and/or the cover member to enable the channel member and the cover member to be snap fitted together.

Abstract: A resuscitation system for use in the resuscitation of a subject includes a computing device configured to input subject information and use the subject information to create a subject resuscitation strategy, a sensor configured to detect subject biosignals and use the subject biosignals to monitor for a subject cardiac arrest event, and a defibrillator configured to determine and deliver a subject resuscitation treatment. On determination of a subject cardiac arrest event, the sensor outputs sensor subject biosignals to the computing device. The computing device uses the sensor subject biosignals to adapt the subject resuscitation strategy and output the subject resuscitation strategy to the defibrillator. The defibrillator measures subject biodata and uses the subject biodata and the subject resuscitation strategy to determine and deliver a subject resuscitation treatment.

Abstract: The present application is directed to biaryl piperidine amide compounds, or pharmaceutically acceptable salts, solvates, and prodrugs thereof, and methods of use thereof.

Abstract: The present invention provides a compound of Formula I: or a pharmaceutically acceptable salt thereof, and the use of compounds of Formula I for treating neurodegenerative diseases, such as Alzheimers disease.

Abstract: The present invention relates to tetrazole containing compounds of general formula (I) as described and defined herein, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease syndrome, condition, or symptoms, in particular related to chronic pain and inflammation, as a sole agent or in combination with other active ingredients.

Abstract: The present disclosure describes a method for conserving power on a portable electronic device and a portable electronic device configured for the same. In accordance with one embodiment, there is provided a method for conserving power comprising: switching a portable electronic device to a low power mode in response to a trigger condition; and switching the portable electronic device from the low power mode to a full power mode on the portable electronic device in response to detection of a designated wake-up gesture on a touch-sensitive overlay of the portable electronic device.

Abstract: The present invention covers substituted. Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

Abstract: Unmanned ground vehicles configured for compact manipulator stowing are disclosed. In some examples, an unmanned ground vehicle includes a main body and a drive system supported by the main body. The drive system includes right and left driven track assemblies mounted on right and left sides of the main body. A manipulator arm is pivotally coupled to the main body and configured to extend from a stowed position to an extended position, and the manipulator arm in the stowed position is contained entirely within a geometric volume of the right and left driven track assemblies.

Abstract: A method disclosed herein includes displaying information associated with a first application in a display area of an electronic device, detecting a change in direction of a continuous gesture across at least a portion of the display area between a first direction and a second direction different than the first direction, the continuous gesture associated with a request to display information of a second application, the first application being different than the second application, in response to detecting the change in direction of the continuous gesture, reducing display of the first application to a first portion of the display area and presenting a preview of information associated with the second application in a second portion of the display area in which the first application was presented prior to detection of the continuous gesture, based on a first characteristic of the continuous gesture, discontinuing providing the first information and display the second application in the display area, and base

Abstract: A ballistically launched foldable multirotor vehicle has a central body frame. A battery is located in an upper vertical location of the vehicle and positions a center of mass of the vehicle to provide aerodynamic stability during a launch. Fins are attached to the central body frame such that aerodynamic forces on the fins shift an aerodynamic center (AC) of the vehicle downward below the center of mass of the vehicle. Three or more foldable arms are attached to the central body frame via a hinge and exist in two states—a closed state where the foldable arms are parallel to a central body axis, and an open state (after launch) where the foldable arms extend radially outward perpendicular to the central body axis. Rotors mounted to each foldable arm are controlled by a motor to enable flight.

Abstract: The present application is directed to biaryl piperidine amide compounds, or pharmaceutically acceptable salts, solvates, and prodrugs thereof, and methods of use thereof.

Abstract: A method disclosed herein includes displaying information associated with a first application in a display area of an electronic device, detecting a change in direction of a continuous gesture across at least a portion of the display area between a first direction and a second direction different than the first direction, the continuous gesture associated with a request to display information of a second application, the first application being different than the second application, in response to detecting the change in direction of the continuous gesture, reducing display of the first application to a first portion of the display area and presenting a preview of information associated with the second application in a second portion of the display area in which the first application was presented prior to detection of the continuous gesture, based on a first characteristic of the continuous gesture, discontinuing providing the first information and display the second application in the display area, and base

Abstract: The invention relates to a low energy spray gun for spraying thin film materials with a thickness of <40 microns such as high performance, thin viscosity nano-paints, lacquers, varnishes and the like. The spray gun comprises a main body (12) having a fluid inlet (14a) connected to an external fluid source (not shown) and a fluid outlet nozzle (16a). Gas outlets (16b-d) on the main body carry entrained fluid droplets emitted from the fluid outlet (14a) the shape of which are controlled by horn outlets (24) positioned beyond the fluid outlet (14a) and gas outlets (16b-d). First and second gas conduits (20, 22) are connected between a common gas inlet (18) and gas outlets (16b-d) and horn outlets (24) respectively. The cross-sectional area of a portion of the first gas conduit (20) is reduced relative to that of the second gas conduit (22) thus creating a pressure drop and a discernible improvement in fluid atomisation.

Abstract: More specifically, the invention relates to providing hand held engravers that can hold a graver closer to parallel to the work while at the same time raising the handle away from the work. The invention is also reversible allowing a graver to be held at a steep angle to the work.

Abstract: A method includes displaying information associated with a first application on a touch-sensitive display of an electronic device. A gesture is detected on the touch-sensitive display, which gesture indicates a request to display information associated with a second application. At least part of the information associated with the second application is displayed without opening the second application.