Patents by Inventor James A. Mabe

James A. Mabe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hinge apparatus with two-way controllable shape memory alloy (SMA) hinge pin actuator and methods of making two-way SMA parts
    Publication number: 20050198777
    Abstract: A hinge apparatus generally includes a hinge pin formed of a two-way shape memory alloy (SMA) adapted to transition, without an externally applied load, between a first trained shape and a second trained shape upon switching the two-way SMA between a first state and a second state. The hinge pin can apply two-way reversible actuation forces to a device coupled to the hinge apparatus. The hinge pin can be produced by thermal cycling a material under a sufficient load for a sufficient number of thermal cycles between about the material's austenite and martensite temperatures to complete training of the material. The thermal cycling conditions the material to transition, without an externally applied load, between an austenitic shape and a martensitic shape to perform useful work when the material is thermally cycled between the austenite and martensite temperatures.
    Type: Application
    Filed: March 9, 2004
    Publication date: September 15, 2005
    Inventor: James Mabe
  • A82846 antibiotics
    Patent number: 5843437
    Abstract: New glycopeptide antibiotic A82846, comprising A82846A, A82846B and A82846C, is produced by Nocardia orientalis strains NRRL 18098, NRRL 18099 and NRRL 18100. The A82846 antibiotics have activity against Gram-positive bacteria comparable to that of vancomycin.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: December 1, 1998
    Assignee: Eli Lilly and Company
    Inventors: Robert L. Hamill, James A. Mabe, David F. Mahoney, Walter M. Nakatsukasa, Raymond C. Yao
  • A83543 compounds and process for production thereof
    Patent number: 5840861
    Abstract: New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
    Type: Grant
    Filed: February 8, 1995
    Date of Patent: November 24, 1998
    Assignee: DowElanco
    Inventors: Jon S. Mynderse, Mary C. Broughton, Walter M. Nakatsukasa, James A. Mabe, Jan R. Turner, Lawrence Creemer, Mary L. B. Huber, Herbert A. Kirst, James W. Martin
  • A83543 compounds and process for production thereof
    Patent number: 5670364
    Abstract: New A83543 components, including fermentation products A83543K, A835430, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 23, 1997
    Assignee: DowElanco
    Inventors: Jon S. Mynderse, James A. Mabe, Jan R. Turner, Mary L. B. Huber, Mary C. Broughton, Walter M. Nakatsukasa, Lawrence Creemer, Herbert A. Kirst, James W. Martin
  • A83543 compounds and process for production thereof
    Patent number: 5670486
    Abstract: New A83543 components, including fermentation products A83543K, A83543O, A83543P, A83543U, A83543V, A83543W and A83543Y and N-demethyl derivatives, and salts thereof, are useful for the control of insects and mites. The pseudoaglycones of the new A83543 components are useful for the preparation of A83543 components. Methods are provided for making the new A83543 components by culturing of Saccharopolyspora spinosa NRRL 18395, NRRL 18537, NRRL 18538, or NRRL 18539, or NRRL 18743 or NRRL 18719 or NRRL 18823 in suitable culture medium. Insecticidal and ectoparasiticidal compositions containing new A83543 components are also provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 23, 1997
    Assignee: DowElanco
    Inventors: Jon S. Mynderse, James A. Mabe, Jan R. Turner, Mary L. B. Huber, Mary C. Broughton, Walter M. Nakatsukasa, Lawrence Creemer, Herbert A. Kirst, James W. Martin
  • A82846 antibiotics
    Patent number: 5312738
    Abstract: New glycopeptide antibiotic A82846, comprising A82846A, A82846B and A82846C, is produced by Nocardia orientalis strains NRRL 18098, NRRL 18099 and NRRL 18100. The A82846 antibiotics have activity against Gram-positive bacteria comparable to that of vancomycin.
    Type: Grant
    Filed: May 9, 1990
    Date of Patent: May 17, 1994
    Assignee: Eli Lilly and Company
    Inventors: Robert L. Hamill, James A. Mabe, David F. Mahoney, Walter M. Nakatsukasa, Raymond C. Yao
  • Recombinant DNA cloning vectors containing selectable genetic markers for use in streptomyces and related organisms
    Patent number: 4698307
    Abstract: The present invention disclosed novel recombinant DNA cloning vectors including pMND1000 and vectors derived therefrom for use in Streptomyces and related organisms. These novel cloning vectors contain genetic markers that provide antibiotic resistance or colorimetric selectivity to the host cells. The invention further comprises transformants of the aforementioned vectors.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: October 6, 1987
    Assignee: Eli Lilly and Company
    Inventors: James A. Mabe, Walter M. Nakatsukasa
  • Recombinant DNA cloning vectors containing selectable genetic markers for use in Streptomyces and related organisms
    Patent number: 4683206
    Abstract: The present invention disclosed novel recombinant DNA cloning vectors for use in Streptomyces and related organisms. These novel cloning vectors contain genetic markers that provide antibiotic resistance or colorimetric selectivity to the host cells. The invention further comprises transformants of the aforementioned vectors.
    Type: Grant
    Filed: August 10, 1984
    Date of Patent: July 28, 1987
    Assignee: Eli Lilly and Company
    Inventors: James A. Mabe, Walter M. Nakatsukasa
  • Functionally independent cloning vectors for use in streptomyces
    Patent number: 4513085
    Abstract: The present invention discloses functionally independent selectable recombinant DNA cloning vectors for use in Streptomyces.
    Type: Grant
    Filed: October 7, 1982
    Date of Patent: April 23, 1985
    Assignee: Eli Lilly and Company
    Inventors: Walter M. Nakatsukasa, James A. Mabe
  • Vectors for cloning in streptomyces
    Patent number: 4468462
    Abstract: The present invention discloses selectable recombinant DNA cloning vectors for use in Streptomyces.
    Type: Grant
    Filed: December 22, 1982
    Date of Patent: August 28, 1984
    Assignee: Eli Lilly and Company
    Inventors: Nancy E. Malin, Jeffrey T. Fayerman, Michael D. Jones, James A. Mabe, Walter M. Nakatsukasa
  • Plasmid pEL7 and related cloning vectors for use in streptomyces and related organisms
    Patent number: 4416994
    Abstract: The present invention discloses selectable pairs of recombinant DNA cloning vectors for use in Streptomyces and related organisms.
    Type: Grant
    Filed: October 19, 1981
    Date of Patent: November 22, 1983
    Assignee: Eli Lilly and Company
    Inventors: Walter M. Nakatsukasa, Jeffrey T. Fayerman, James A. Mabe