Abstract: The present invention relates to compounds, compositions, and methods for the study, diagnosis, and treatment of traits, diseases and conditions that respond to the modulation of gene expression and/or activity, and/or modulate a gene expression pathway. Specifically, the invention relates to double-stranded nucleic acid molecules including small nucleic acid molecules, such as short interfering nucleic acid (siNA) molecules that are capable of mediating or that mediate RNA interference (RNAi) against target gene expression.

Abstract: A print component includes an array of fluidic actuation structures including a first column of fluidic actuating structures addressable by a set of actuation addresses, each fluidic actuating structure having a different one of the actuation addresses and having a fluidic architecture type, and a second column of fluidic actuating structures addressable by the set of actuation addresses. Each fluidic actuating structure of the second column has a different one of the actuation addresses and has a same fluidic architecture type as the fluidic actuating structure of the first column having the same address. An address bus communicates the set of addresses to the array of fluidic actuating structures, and a fire signal line communicates a plurality of fire pulse signal types to the array of fluidic actuating structures, the fire pulse signal type depending on the actuation address on the address bus.

Abstract: A twist-tie dispenser comprises a twist-tie cluster and a base. The base includes a top portion, a rear wall extending downward from the top portion, and an open front.

Abstract: A system for disinfecting an autonomous vehicle includes a light assembly having LEDs configured to emit UVC light into a passenger compartment of the autonomous vehicle. The light assembly includes a heat sink to dissipate heat generated by the LEDs. In examples, the heat sink is disposed in the path of forced air associated with a climate control system of the vehicle. The climate control system may be controlled based on a temperature proximate the LEDs and/or the heat sink. In some examples, the light assembly is integrated into the ceiling of the vehicle and can further include visible light emitters and/or other features.

Abstract: Aeroponics apparatus for commercial operation is disclosed, the aeroponics apparatus including a support structure comprising a power supply device, at least one shuttle movable on the support structure, the shuttle comprising a grow bed tray for holding crops, the shuttle comprising one or more nebulizers, for generating an aerosol for fertigating the crops in the grow bed tray, and a power connector to connect to the power supply device to supply power to the shuttle.

Abstract: An environmental-efficiency fluid is designed by a system and/or method. The fluid can be for use in a down-hole operation in a well. The design produces the environmental-efficiency fluid from a treatment fluid and drill cuttings. For example, the system and method can include creating an analysis of a rheological model generated from a set of wellbore conditions and a set of drill-cutting properties to determine a set of rheological properties for the treatment fluid and a concentration of drill cuttings, which allow for use of the drill cuttings with the treatment fluid; and producing the environmental-efficiency fluid based on the rheological properties and the concentration of drill cuttings.

Abstract: A method for determining a health indicator parameter of a fluid are described. The method can include contacting at least one first functionalized electrode included in a plurality of functionalized electrodes of a sensing unit with a fluid. The method can also include generating a first electrical signal within the fluid by the at least one first functionalized electrode. The method can further include receiving, by at least one second functionalized electrode included in the plurality of functionalized electrodes of the sensing unit, a second electrical signal in response to the first electrical signal. The sensing unit can determine a health indicator parameter of the fluid based on the second electrical signal. The health indicator parameter can be associated with an electrochemical response signal included in the second electrical signal. The sensing unit can provide the health indicator parameter to a computing device communicably coupled to the sensing unit.

Abstract: Methods, systems, and computer-readable media for a service for managing quantum computing resources are disclosed. A task management service receives a description of a task specified by a client. From a pool of computing resources of a provider network, the service selects a quantum computing resource for implementation of the task. The quantum computing resource comprises a plurality of quantum bits. The service causes the quantum computing resource to run a quantum algorithm associated with the task. The service receives one or more results of the quantum algorithm from the quantum computing resource.

Abstract: A system and method are provided for controlling a plurality of fuel cells. The method includes coordinating a distribution of a power demand in response to a power request of a power system comprising a plurality of fuel cells, the power output of each of the fuel cells selected based on a respective efficiency of each of the fuel cells.

Abstract: Apparatus for x-ray CT scanning of an object includes an x-ray generator 1 mounted on a first support 3 on an outer ring 4 and an x-ray detector 2 mounted on a second support 10 on an inner ring 11, and a drive mechanism arranged to rotate the outer and inner rings 4, 11. The outer and inner rings have a first common axis of rotation and the diameter of the outer ring 4 is greater than the diameter of the inner ring 11 The drive mechanism includes a gearing arrangement connecting the outer and inner rings 4,11. The gearing arrangement comprises first and second toothed rotary gears 14,16.

Abstract: A system for operating and/or lubricating a plurality of valves. The system includes at least first and second control units, each of which is associated with a respective valve. Each control unit includes a hydraulic pressure inlet, a hydraulic pressure outlet, a hydraulic pressure line connected between the hydraulic pressure inlet and the hydraulic pressure outlet, and a hydraulic port which is connectable to the valve. The hydraulic pressure inlet of the first control unit is connectable to a hydraulic pressure source and the hydraulic pressure outlet of the first control unit is connectable to the hydraulic pressure inlet of the second control unit. In operation, the control unit is operable to selectively communicate hydraulic pressure from the hydraulic pressure line to the hydraulic port.

Abstract: An electrode material for a lithium ion secondary battery and method of forming the same, the electrode material including composite particles, each composite particle including: a primary particle including an electrochemically active material; and an envelope disposed on the surface of the primary particle. The envelope includes turbostratic carbon having a Raman spectrum having: a D band having a peak intensity (ID) at wave number between 1330 cm-1 and 1360 cm-1; a G band having a peak intensity (IG) at wave number between 1530 cm-1 and 1580 cm-1; and a 2D band having a peak intensity (I2D) at wave number between 2650 cm-1 and 2750 cm-1. In one embodiment, a ratio of ID/IG ranges from greater than zero to about 1.1, and a ratio of I2D/IG ranges from about 0.4 to about 2.

Abstract: As a farming machine travels through a field of plants, the farming machine operates in a normal operational state to perform one or more farming operations. The farming machine detects an operational failure of a component of the farming machine using measurements obtained from one or more sensors coupled to and monitoring the farming machine. The operational failure of the component impacts performance of a first farming operation of the farming operations. The farming machine configures the farming machine to operate in a remedial operational state. In the remedial operational state, the farming machine diagnoses the operational failure of the component using the obtained measurements. In the remedial operational state, the farming machine selects a solution operation to address the operational failure of the component based on the diagnosis. The farming machine performs the determined solution operation.

Abstract: Methodologies to detect off-target mutations induced by the deaminase activity of Base Editing technology.

Abstract: Dynamically generating data tests includes: receiving test templates and metadata for a plurality of data objects and, on a trigger condition: based on at least the metadata and the test templates, determining a current set of templated data tests, wherein determining the current set of templated data tests comprises: determining at least one templated data test, from a prior set of templated data tests, to cease using; determining at least one templated data test to add to the current set of templated data tests; and determining, within the current set of templated data tests, at least one templated data tests to regenerate; generating the at least one templated data test to add to the current set of templated data tests; regenerating the least one templated data test to regenerate; and executing templated data tests, within the set of current templated data tests, on the plurality of data objects.

Abstract: An implantable medical device, including a magnet and a body encompassing the magnet, wherein the implantable medical device includes structural components in the body configured to move away from one another upon initial rotation of the magnet relative to the body when the magnet is subjected to an externally generated magnetic field, thereby limiting rotation of the magnet beyond the initial rotation.

Abstract: A joist assembly system that is structured for dynamic retrieval of components, dynamic and precise positioning and location of retrieved components, assembly of the components to form a joist, and delivery of the assembled joist. The joist assembly system has a plurality of material handling systems, a plurality of welding systems, and a rigging table system. The material handling systems are structured to load and position the components such as chords and webs onto the rigging table. The rigging table in turn supports the chords or webs. Subsequently, the plurality of welding systems weld the webs to the chords to form the joist.

Abstract: A semiconductor wafer imaging system for imaging a semiconductor wafer includes shroud panels defining a black box, a camera positioned in the black box for imaging the semiconductor wafer, and an illumination panel for directing diffuse light to the semiconductor wafer. A portion of the diffuse light is reflected off the semiconductor wafer and the camera images the semiconductor wafer by detecting the reflected diffuse light.

Abstract: Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that may include a connector port subassembly. The connector port subassembly may include one or more connector blocks configured to interference fit within a connector bore, one or more windows through the core subassembly to the one or more connector blocks, and one or more seal rings configured to interference fit within the connector bore and eliminate adulterant entry into the connector bore through the one or more windows.

Abstract: HIPAA-compliant computer security method and system for recording, using a video camera, electronic visual personal health information of at least two individuals, including an individual under care, and preventing unauthorized access of the user to the video information. The video is compared to physical attribute information of the individuals stored in the computer system's memory, and the individuals are identified by facial matching. The user's stored caseload has authorization profile information including access to individuals under care. The identified individuals are compared to the user's caseload information, and the user is granted access to part of the video of the individual under care, the video of the other individuals is blurred, and the resulting video is transmitted to the user's caseload for viewing. Data fields of an information request are populated using formatted data from the video information.