Patents by Inventor James A. Murto

James A. Murto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240200871
    Abstract: Assemblies, systems, and methods for preventing contamination and alteration of a biological material during and after freeze-drying processes are disclosed. Tray assemblies configured to hold the biological material in a container during a freeze-drying process include a tray and complementary lid. The lid can include compressible leg members configured to transition from an extended configuration to a compressed configuration in response to a downward force applied against the lid when the lid is positioned above the tray. A gap exists between an upper edge of the tray and an underside of the lid when the leg members are extended. With the legs extended and the tray assembly open, the tray assembly is freeze-dried. After freeze-drying is complete, the legs can be compressed and the lid sealed against the tray, enclosing the biological material within the assembly, and protecting it from contamination and ambient air exposure within and outside the chamber.
    Type: Application
    Filed: December 20, 2023
    Publication date: June 20, 2024
    Applicant: Teleflex Life Sciences LLC
    Inventors: James A. Murto, Stephen A. Penegor
  • Patent number: 11279510
    Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: March 22, 2022
    Assignee: Teleflex Life Sciences Limited
    Inventors: Howard Root, Stephen Anthony Penegor, James A. Murto
  • Patent number: 10945959
    Abstract: A system and method for freeze-drying a heat-sensitive substance. In some embodiments, the system and method include freeze-drying the heat-sensitive substance in an upright container with a membrane for transmitting air or vapor solvent out of the container.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: March 16, 2021
    Assignee: Teleflex Life Sciences Limited
    Inventors: James A. Murto, Stephen Anthony Penegor
  • Publication number: 20210039820
    Abstract: A system and method for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, a membrane configured to transmit air or solvent vapor out of the flexible container, and a membrane frame supporting the membrane and engaged with at least one column member. The at least one column member can be configured to maintain the membrane and the membrane frame a spaced distance from one or more contents received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration. A method can include inserting a biological material, for example, into a flexible container, freeze-drying the biological material, moving the freeze-dried biological material to a portion of the flexible container that includes at least one port, and sealing the biological material within the portion.
    Type: Application
    Filed: October 26, 2020
    Publication date: February 11, 2021
    Applicant: Teleflex Life Sciences Limited
    Inventors: Howard Root, Stephen Anthony Penegor, James A. Murto
  • Patent number: 10806665
    Abstract: Systems and methods for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, at least two membranes configured to transmit air or solvent vapor out of the flexible container, and a port to allow for the introduction or withdrawal of a material or substance into or out of the flexible container. The system can optionally further comprise a membrane frame supporting at least one of the membranes and engaged with at least one column member. The at least one column member can be configured to maintain the membranes and the membrane frame a spaced distance from one or more materials received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: October 20, 2020
    Assignee: Teleflex Life Sciences Limited
    Inventors: James A. Murto, Stephen A. Penegor
  • Publication number: 20200281858
    Abstract: A system and method for freeze-drying a heat-sensitive substance. In some embodiments, the system and method include freeze-drying the heat-sensitive substance in an upright container with a membrane for transmitting air or vapor solvent out of the container.
    Type: Application
    Filed: March 7, 2019
    Publication date: September 10, 2020
    Inventors: James A. Murto, Stephen Anthony Penegor
  • Publication number: 20170203871
    Abstract: Systems and methods for protecting biological or other material from contamination through the steps of filling, freeze-drying, packaging, storing and use are disclosed. A system can include a flexible container, at least two membranes configured to transmit air or solvent vapor out of the flexible container, and a port to allow for the introduction or withdrawal of a material or substance into or out of the flexible container. The system can optionally further comprise a membrane frame supporting at least one of the membranes and engaged with at least one column member. The at least one column member can be configured to maintain the membranes and the membrane frame a spaced distance from one or more materials received within the flexible container. Upon application of a downward force, the at least one column member can assume a collapsed configuration.
    Type: Application
    Filed: November 4, 2016
    Publication date: July 20, 2017
    Inventors: James A. Murto, Stephen A. Penegor
  • Publication number: 20040243044
    Abstract: A hemostatic dressing for applying a hemostatic material such as lyophilized thrombin to a wound. The wound dressing includes an impermeable backing material and a sealing member to provide a seal against the skin. The wound dressing enables the application of pressure in order to seal the sealing member against the patient's skin to the wound without the need for attendance by a health care professional. The seal may be applied by a compressive band or by application of a pressure sensitive adhesive. The wound dressing creates a sealed localized procoagulation environment to facilitate the formation of a clot initiated by the presence of substantial quantities of externally supplied lyophilized thrombin or another dry coagulant.
    Type: Application
    Filed: June 2, 2003
    Publication date: December 2, 2004
    Inventors: Stephen A. Penegor, Howard Root, James A. Murto