Abstract: A seal for a bottle and cap assembly. The seal is formed from a heat shrink sheet which is adhesively coated on one side. A pull tab is formed by a pair of cuts in one edge of the sheet forming the seal and a tear strip is adhesively secured to the back of the sheet in registration with the pull tab. After being adhesively secured to a bottle and cap assembly, the sheet is heat shrunk to conform to the contour of the bottle and to provide a flange over the bottle cap. In one embodiment the pull tab is in registration with the area of joinder between the cap and the bottle and in another, the sheet is devoid of adhesive in an area extending from the pull tab and bridging the joinder between the cap and bottle. In either case, pulling of the pull tab separates the sheet into a first piece adhered to the cap and a second piece adhered to the bottle allowing for the only possible access to the bottle without evidence of tampering showing in the sheet.