Abstract: There is provided a valve assembly suitable for use in a high temperature well, such as a geothermal well. The valve assembly comprises a tubular housing having ports to allow fluid communication between a fluid passageway in the valve assembly and the outside of the valve assembly, an outer sleeve longitudinally slidable in the tubular housing, and an inner sleeve longitudinally slidable in the outer sleeve. The outer and inner sleeves are slidable to various positions to prevent, allow or restrict flow through the ports. The valve assembly may include sealing assemblies that can withstand high temperatures, frangible plugs in the ports that can be sheared to open the ports, and/or a coupling member for coupling the inner and outer sleeve while the ports are being opened. The valve assembly may have ports configured in a manner that allows for sequential opening of the ports.

Abstract: There is provided an apparatus for pulse charging of a load capacitor, the apparatus comprising: a ferrous cored transformer having a primary winding and a secondary winding; a primary circuit connected to the primary winding; a secondary circuit connected to the secondary winding, the secondary circuit comprising the load capacitor; and an uncoupled inductance in the primary circuit or the secondary circuit, the uncoupled inductance reducing the coupling coefficient between the primary circuit and the secondary circuit.

Abstract: A system is disclosed herein, including a cushion including a plurality of tactors and a plurality of air bladders disposed adjacent the plurality of tactors, a pump assembly operably connected to the plurality of bladders, a processor, and a memory operatively coupled to the processor. The memory includes instructions stored thereon that, when executed by the processor, cause the processor to determine an inflation sequence for the plurality of air bladders, determine a deflation sequence for the plurality of air bladders, output commands to the pump assembly corresponding to the inflation sequence and the deflation sequence, and output vibrate commands to the plurality of tactors.

Abstract: The present disclosure relates to a leak-proof vessel for storing fluid that comprises a cylindrical body for storing a fluid. The cylindrical body includes a neck portion, which includes a threaded interior surface that enables seamless sealing with a threaded exterior surface of an inner lid. The inner lid comprises a disk plate with an orifice and an air vent, wherein one or more grooves are formed on an interior surface of the inner lid. Further the leak-proof vessel comprises an outer lid including one or more locking elements, wherein the one or more locking elements interlock with the one or more grooves to firmly engage the inner lid with the outer lid. Further, a base aperture securely holds the outer lid within the base aperture, for providing a hands-free experience to a user.

Abstract: The present disclosure relates to topical treatment of skin diseases, such as psoriasis, atopic dermatitis, alopecia, vitiligo, Reiter's syndrome, pityriasis rubra pilaris, epidermolysis bullosa simplex, palmoplantar keratoderma, pachyonychia congenita, steatocystoma multiplex, cutaneous lichen planus, cutaneous T-cell lymphoma, hidradenitis suppurativa, contact dermatitis, ichthyosis, and a disorder of keratinization, using (a) a JAK inhibitor, or a pharmaceutically acceptable salt thereof, and (b) vitamin D3, a vitamin D3 analog, or a pharmaceutically acceptable salt thereof.

Abstract: A sensor apparatus includes a substrate, a semiconductor device disposed over the substrate, the semiconductor device having a surface electrode structure, and a saccharide coating formed over the surface electrode structure. The saccharide coating can be removed prior to use. The semiconductor device can further include a well and optionally a bead disposed in the well.

Abstract: An endurance haptic system is disclosed herein. The endurance haptic system includes a plurality of tactors, a plurality of air bladders, a tactor driver operably coupled to the plurality of tactors and configured to send vibration commands to the plurality of tactors in response to a first signal received from an aircraft controller, and an air bladder driver operably coupled to the plurality of air bladders and configured to inflate and deflate the plurality of air bladders in response to a second signal received from the aircraft controller.

Abstract: In some examples, an array sensor temperature control system is provided. The system may include an array sensor for generating a two-dimensional image, the two-dimensional image including a plurality of pixels or cells indicative of a temperature of a monitored component; a controller for controlling a heating or cooling device to adjust the temperature of the monitored component; and an array sensor controller activated by a power source and being in communication with the array sensor and controller.

Abstract: A material reduction machine includes an infeed portion operable to receive material to be reduced, and a cutting mechanism operable to reduce material fed in from the infeed portion. An outlet chute has a first end operable to receive the material reduced by the cutting mechanism and a second end operable to discharge the reduced material from the machine, wherein the outlet chute extends along a curved path. The outlet chute includes, along a radially-inner side of the curved path, a foraminous interior wall providing communication with a sound attenuation layer.

Abstract: A fixture for removably securing a plurality of components includes a hollow body including a plurality of channels and a plurality of sets of holes. The fixture further includes a plurality of hollow wedges and a plurality of sets of balls. Upon an axial movement of an elongate member in a first direction, the elongate member axially moves a first hollow wedge, thereby causing one or more elastic members to be sequentially compressed and move the subsequent hollow wedges. Upon the axial movement, a frustoconical surface portion of each hollow wedge moves the corresponding set of balls radially outwards within the corresponding set of holes, such that each ball extends partially into the corresponding channel, thereby moving the corresponding component into locking engagement with the corresponding channel.

Abstract: In some examples, an array sensor temperature control system is provided. The system may include an array sensor for generating a two-dimensional image, the two-dimensional image including a plurality of pixels or cells indicative of a temperature of a monitored component; a controller for controlling a heating or cooling device to adjust the temperature of the monitored component; and an array sensor controller activated by a power source and being in communication with the array sensor and controller.

Abstract: A storytelling interface comprising a map panel and a genealogy panel, and methods for using the same, are described. The storytelling interface facilitates dynamic and automatic scaling and relocation of the map panel based on a user's location within the genealogy panel, which facilitates a continuous scrolling operation to navigate between different sections of the genealogy panel. The storytelling interface facilitates a user receiving, viewing, and interacting with DNA and ethnic communities results determined from DNA testing, and allows a user to navigate through pertinent communities in both time and/or space.

Abstract: The present invention relates to specific binding molecules, such as T cell receptors (TCRs), that bind the HLA-A*02 restricted peptide KVLEYVIKV (SEQ ID NO: 1) derived from the germline cancer antigen MAGEA1. The specific binding molecules may comprise non-natural mutations within the alpha and/or beta variable domains relative to a native MAGEA1 TCR. The specific binding molecules of the invention are particularly suitable for use as novel immunotherapeutic reagents for the treatment of malignant disease.

Abstract: Various embodiments include methods and apparatuses to test production tools and related electrical components therefor including individual printed-circuit boards (PCBs). In one example, a test-plug hardware-platform includes at least one input/output (I/O) connector, and a configurable control system to provide command and operational signals through the I/O connector and collect data through the I/O connector from at least one PCB under test. A wireless-mesh network within the test-plug hardware-platform can interface wirelessly with at least the PCB under test. The at least one PCB operating within a production tool or other piece of equipment. Other methods and systems are disclosed.

Abstract: A computer-implemented method according to one embodiment includes embedding natural language processing (NLP) and/or user action capture into a browser to monitor a user's intent when navigating web page(s) within the browser. An indication of a navigation to a first web page via the browser is received and it is determined whether a first action attempted to be taken on the first web page matches the user's intent. In response to a determination that the first action attempted to be taken on the first web page does not match the user's intent, an intent-based blocking action is issued to prevent the first action on the first web page. A computer program product according to another embodiment includes a computer readable storage medium having program instructions embodied therewith. The program instructions are readable and/or executable by a computer to cause the computer to perform the foregoing method.

Abstract: A vehicle component balancing robot apparatus, system and method for on vehicle balancing of one or more of a tire, a wheel, bearings, brake components, and vehicle components that impart vibrations to the vehicle. The apparatus includes a frame arranged so as to connect with the vehicle. A robot of the apparatus moves relative to the frame, and is configured so that the move, relative to the frame, resolves a predetermined location of a tire-wheel assembly relative to a reference frame of the robot. The robot has at least one end effector arranged to interface the tire-wheel assembly and the robot moves the at least one end effector to other predetermined locations on a wheel rim of the tire-wheel assembly, determined based on resolution of the predetermined location of the tire-wheel assembly relative to the reference frame.

Abstract: A vehicle component balancing robot apparatus, for on vehicle balancing of one or more of a tire, a wheel, bearings, brake components, and vehicle components that impart vibrations to the vehicle. The apparatus includes a frame arranged so as to connect with the vehicle. A robot of the apparatus moves relative to the frame, and is configured so that the move, relative to the frame, resolves a predetermined location of a tire-wheel assembly relative to a reference frame of the robot. The robot has at least one end effector arranged to interface the tire-wheel assembly and the robot moves the at least one end effector to other predetermined locations on a wheel rim of the tire-wheel assembly, determined based on resolution of the predetermined location of the tire-wheel assembly relative to the reference frame.

Abstract: Disclosed is a configuration for determining a genotyping label composition of a target individual using direct acyclic paths. The configuration includes receiving a phased genotype of the target individual, including a first haplotype and a second haplotype. The configuration initiates a full-ethnicity hidden Markov model (HMM) including nodes with a set of ethnicity labels. The first haplotype is input to determine a first subset of ethnicity labels that match the first haplotype. The second haplotype is input to determine a second subset of ethnicity labels that match the second haplotype. The first and second subsets of ethnicity labels are combined to create a candidate subset of ethnicity labels for the target individual. The configuration initiates a simplified HMM with nodes from the candidate subset of ethnicity labels. The phased genotype of the target individual is input to the simplified HMM to determine genotyping label composition of the target individual.

Abstract: Techniques for limiting unwanted comments are described. For example, a social networking system may receive, from a first account of the social networking system, a request to post content. In some examples, the social networking system may further receive an instruction to limit an ability of certain accounts lacking a characteristic from commenting on the first account’s content. In some cases, the social networking system may receive, from a second account. Upon determining that the second account lacks the characteristic, the social networking system may refrain from sharing the comment with one or more additional users.