Abstract: The present disclosure provides methods of treating subjects having increased lipid levels, methods of identifying subjects having an increased risk of developing an increased lipid level, methods of detecting human Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) variant nucleic acid molecules and variant polypeptides, and SREBF1 variant nucleic acid molecules and variant polypeptides.

Abstract: The present disclosure provides methods of treating subjects having increased lipid levels, methods of identifying subjects having an increased risk of developing an increased lipid level, methods of detecting human Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) variant nucleic acid molecules and variant polypeptides, and SREBF1 variant nucleic acid molecules and variant polypeptides.

Abstract: The present disclosure provides methods of treating subjects having increased lipid levels and/or increased triglyceride levels, methods of identifying subjects having an increased risk of developing an increased lipid level and/or increased triglyceride level, methods of detecting human Sterol Regulatory Element Binding Protein Cleavage-Activating Protein (SCAP) variant nucleic acid molecules and variant polypeptides, and SCAP variant nucleic acid molecules and variant polypeptides.

Abstract: The present disclosure provides methods of treating subjects having increased lipid levels and/or increased triglyceride levels, methods of identifying subjects having an increased risk of developing an increased lipid level and/or increased triglyceride level, methods of detecting human Sterol Regulatory Element Binding Protein Cleavage-Activating Protein (SCAP) variant nucleic acid molecules and variant polypeptides, and SCAP variant nucleic acid molecules and variant polypeptides.

Abstract: The present disclosure provides methods of treating subjects having increased lipid levels and/or increased triglyceride levels, methods of identifying subjects having an increased risk of developing an increased lipid level and/or increased triglyceride level, methods of detecting human Sterol Regulatory Element Binding Protein Cleavage-Activating Protein (SCAP) variant nucleic acid molecules and variant polypeptides, and SCAP variant nucleic acid molecules and variant polypeptides.

Abstract: The present disclosure provides methods of treating subjects having increased lipid levels, methods of identifying subjects having an increased risk of developing an increased lipid level, methods of detecting human Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1) variant nucleic acid molecules and variant polypeptides, and SREBF1 variant nucleic acid molecules and variant polypeptides.

Abstract: A load bearing lift attachment apparatus for a multipurpose loader bucket including a first jaw and a second jaw movably mounted thereto between an opened condition and a closed condition. The lift attachment apparatus includes a lift member formed and dimensioned to engage an object to be lifted; and a lift support device removably coupling the lift member to the loader bucket. The lift support device is configured to cooperate with the first jaw and the second jaw, in the closed condition, to distribute the cantilever forces, caused by the weight of the object acting on the loader bucket, across a substantial transverse portion of a support member of the first jaw and a rear engaging wall of the second jaw.

Abstract: A load bearing lift attachment apparatus for a multipurpose loader bucket including a first jaw and a second jaw movably mounted thereto between an opened condition and a closed condition. The lift attachment apparatus includes a lift member formed and dimensioned to engage an object to be lifted; and a lift support device removably coupling the lift member to the loader bucket. The lift support device is configured to cooperate with the first jaw, and the top surface and the bottom surface of the engaging wall of the second jaw, in the closed condition, to distribute the cantilever forces, caused by the weight of the object acting on the loader bucket, across a substantial transverse portion of a support member of the first jaw and a engaging wall of the second jaw.

Abstract: A load bearing lift attachment apparatus for a multipurpose loader bucket including a first jaw and a second jaw movably mounted thereto between an opened condition and a closed condition. The lift attachment apparatus includes a lift member formed and dimensioned to engage an object to be lifted; and a lift support device removably coupling the lift member to the loader bucket. The lift support device is configured to cooperate with the first jaw and the second jaw, in the closed condition, to distribute the cantilever forces, caused by the weight of the object acting on the loader bucket, across a substantial transverse portion of a support member of the first jaw and a rear engaging wall of the second jaw.

Abstract: A load bearing lift attachment apparatus for a multipurpose loader bucket including a first jaw and a second jaw movably mounted thereto between an opened condition and a closed condition. The lift attachment apparatus includes a lift member formed and dimensioned to engage an object to be lifted; and a lift support device removably coupling the lift member to the loader bucket. The lift support device is configured to cooperate with the first jaw, and the top surface and the bottom surface of the engaging wall of the second jaw, in the closed condition, to distribute the cantilever forces, caused by the weight of the object acting on the loader bucket, across a substantial transverse portion of a support member of the first jaw and a engaging wall of the second jaw.

Abstract: A load bearing lift attachment apparatus for a multipurpose loader bucket including a first jaw and a second jaw movably mounted thereto between an opened condition and a closed condition. The lift attachment apparatus includes a lift member formed and dimensioned to engage an object to be lifted; and a lift support device removably coupling the lift member to the loader bucket. The lift support device is configured to cooperate with the first jaw and the second jaw, in the closed condition, to distribute the cantilever forces, caused by the weight of the object acting on the loader bucket, across a substantial transverse portion of a support member of the first jaw and a rear engaging wall of the second jaw.