Abstract: A sample measuring apparatus is disclosed. In the preferred embodiment, a syringe having a set of calibrations is used to collect a specimen. The syringe has a set of calibrations which are offset from actual zero. The extent of offset accommodates the connecting volume found in a sample injection valve between the end of the syringe's outlet and the front of the portion of the sample actually injected. This enables the sample to be injected into a high resolution liquid chromatography column when an injection valve is switched. This enables the injection of a specified calibrated sample. Moreover, sufficient sample is injected to overcome the connecting volume or offset occurring in the injection valve where a connecting volume in the valve captures and holds a certain portion of the specimen. This connecting volume is held to a practical minimum.