Patents by Inventor James A. Romesser

James A. Romesser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110065122
    Abstract: A method of interfering with quorum sensing regulation of genes to promote cell growth is disclosed. The method of is aimed at accessing microbial biodiversity. The method involves obtaining an environmental sample comprising at least one novel (uncultivated in the laboratory) microorganism, contacting the environmental sample with an effective amount of an agent or combination of agents which interferes with the quorum sensing regulation of genes, growing the treated sample in a culture medium containing the quorum sensing signal disrupting agent or agents, and analyzing the colonies of microorganisms grown to demonstrate genetic novelty.
    Type: Application
    Filed: November 24, 2010
    Publication date: March 17, 2011
    Applicant: Fraunhofer USA, Inc.
    Inventors: Carla H. Kuhner, Barry Marrs, James A. Romesser
  • Publication number: 20090130688
    Abstract: A method of interfering with quorum sensing regulation of genes to promote cell growth is disclosed. The method of is aimed at accessing microbial biodiversity. The method involves obtaining an environmental sample comprising at least one novel (uncultivated in the laboratory) microorganism, contacting the environmental sample with an effective amount of an agent or combination of agents which interferes with the quorum sensing regulation of genes, growing the treated sample in a culture medium containing the quorum sensing signal disrupting agent or agents, and analyzing the colonies of microorganisms grown to demonstrate genetic novelty.
    Type: Application
    Filed: January 27, 2009
    Publication date: May 21, 2009
    Inventors: Carla H. Kuhner, Barry Marrs, James A. Romesser
  • Patent number: 7494810
    Abstract: A method of interfering with quorum sensing regulation of genes to promote cell growth is disclosed. The method of is aimed at accessing microbial biodiversity. The method involves obtaining an environmental sample comprising at least one novel (uncultivated in the laboratory) microorganism, contacting the environmental sample with an effective amount of an agent or combination of agents which interferes with the quorum sensing regulation of genes, growing the treated sample in a culture medium containing the quorum sensing signal disrupting agent or agents, and analyzing the colonies of microorganisms grown to demonstrate genetic novelty.
    Type: Grant
    Filed: January 22, 2003
    Date of Patent: February 24, 2009
    Assignee: Franhofer USA Incorporated
    Inventors: Carla H. Kuhner, Barry Marrs, James A. Romesser
  • Publication number: 20080038767
    Abstract: A method of interfering with quorum sensing regulation of genes to promote cell growth is disclosed. The method of is aimed at accessing microbial biodiversity. The method involves obtaining an environmental sample comprising at least one novel (uncultivated in the laboratory) microorganism, contacting the environmental sample with an effective amount of an agent or combination of agents which interferes with the quorum sensing regulation of genes, growing the treated sample in a culture medium containing the quorum sensing signal disrupting agent or agents, and analyzing the colonies of microorganisms grown to demonstrate genetic novelty.
    Type: Application
    Filed: March 29, 2007
    Publication date: February 14, 2008
    Applicant: Athena Biotechnologies, Inc.
    Inventors: Carla Kuhner, Barry Marrs, James Romesser
  • Patent number: 6858581
    Abstract: Compositions and methods for inhibiting and controlling the growth of microbes are disclosed. The composition comprises at least one chemically-modified peptide with antimicrobial activity and at least one carrier. The method comprises of administering an amount, effective for the prevention, inhibition and termination of microbial growth for industrial, pharmaceutical, household and personal care use.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: February 22, 2005
    Assignee: Arizona State University
    Inventors: Carla H. Kuhner, James A. Romesser
  • Publication number: 20040038374
    Abstract: A method of interfering with quorum sensing regulation of genes to promote cell growth is disclosed. The method of is aimed at accessing microbial biodiversity. The method involves obtaining an environmental sample comprising at least one novel (uncultivated in the laboratory) microorganism, contacting the environmental sample with an effective amount of an agent or combination of agents which interferes with the quorum sensing regulation of genes, growing the treated sample in a culture medium containing the quorum sensing signal disrupting agent or agents, and analyzing the colonies of microorganisms grown to demonstrate genetic novelty.
    Type: Application
    Filed: January 22, 2003
    Publication date: February 26, 2004
    Inventors: Carla H. Kuhner, Barry Marrs, James A. Romesser
  • Publication number: 20040023254
    Abstract: A method for detecting quorum sensing potential in a sample is provided comprising extracting nucleic acid from a sample comprising at least one type of microorganism; performing a polymerase chain reaction on the nucleic acid using oligonucleotide primers, wherein each of the primers comprises at least 15 nucleobases and anneal to a consensus sequence of a lux gene and homologs thereof, wherein the first eight nucleobases at the 3′ end of the primers comprise a match to said consensus sequence with optional degeneracy at positions 4-8 from the 3′ end of the primers; separating the amplified DNA fragments; and determining whether any amplified DNA fragment corresponds to the size of a predicted product related to quorum sensing potential. Methods of amplifying fragments of lux genes and homologs thereof are also provided as well as isolated nucleic acid fragments of lux and kits for performing PCR reactions.
    Type: Application
    Filed: January 7, 2003
    Publication date: February 5, 2004
    Inventors: Jeffry J. Fuhrmann, James A. Romesser
  • Publication number: 20030194445
    Abstract: Peptide compositions and methods for inhibiting and controlling the growth of microbes using peptides possessing antimicrobial activity are described. The composition comprises at least one antimicrobial peptide in combination with at least one biocide, germicide, preservative or antibiotic. The method comprises administering an amount of the peptide composition effective for the prevention, inhibition or termination of microbes in industrial and clinical settings.
    Type: Application
    Filed: November 12, 2001
    Publication date: October 16, 2003
    Inventors: Carla H. Kuhner, James A. Romesser
  • Publication number: 20030050247
    Abstract: Compositions and methods for inhibiting and controlling the growth of microbes are disclosed. The composition comprises at least one chemically-modified peptide with antimicrobial activity and at least one carrier. The method comprises of administering an amount, effective for the prevention, inhibition and termination of microbial growth for industrial, pharmaceutical, household and personal care use.
    Type: Application
    Filed: June 15, 2001
    Publication date: March 13, 2003
    Inventors: Carla H. Kuhner, James A. Romesser
  • Publication number: 20020051819
    Abstract: Peptides, compositions and methods for inhibiting and controlling the growth of Burkholderia cepacia are disclosed. The composition comprises a peptide mixture with antimicrobial activity against Burkholderia cepacia and at least one carrier. The method comprises delivering an amount, effective for the prevention, inhibition and termination of the growth of Burkholderia cepacia for industrial, pharmaceutical, household, and personal care use.
    Type: Application
    Filed: June 15, 2001
    Publication date: May 2, 2002
    Inventors: Carla H. Kuhner, James A. Romesser
  • Patent number: 5349127
    Abstract: DNA sequences encoding herbicide metabolizing cytochrome P450 enzymes and iron-sulfur proteins that donate electrons to these enzymes, were introduced into plants and microorganisms rendering them able to produce the encoded gene products and to metabolize herbicides.
    Type: Grant
    Filed: October 26, 1992
    Date of Patent: September 20, 1994
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Caroline Dean, Patricia A. Harder, Kenneth J. Leto, Daniel P. O'Keefe, Charles A. Omer, James A. Romesser, James M. Tepperman
  • Patent number: 5295985
    Abstract: The invention provides novel polyesters, fibers and films, nonwovens from the fibers and disposable products of the polyesters such as diapers. The products are degradable under the conditions typically existing in waste compositing processes, have low ingredient costs and yet provide strength and toughness properties adequate for end uses such as in disposable diapers. The polyesters are based upon polyester ingredients, such as polyethylene terephthalate, copolymerized with an alkali metal or alkaline earth metal 4-sulfophthalic acid derivative, and other ingredients, such as polyethylene ether glycols and/or non-aromatic diacids, such as adipic and glutaric acids.
    Type: Grant
    Filed: November 6, 1992
    Date of Patent: March 22, 1994
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: James A. Romesser, Hyunkook Shin, Raymond F. Tietz
  • Patent number: 5212296
    Abstract: DNA sequences encoding herbicide metabolizing cytochrome P450 enzymes and iron-sulfur proteins that donate electrons to these enzymes, were introduced into plants and microorganisms rendering them able to produce the encoded gene products and to metabolize herbicides.
    Type: Grant
    Filed: August 23, 1990
    Date of Patent: May 18, 1993
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Caroline Dean, Patricia A. Harder, Kenneth J. Leto, Daniel P. O'Keefe, Charles A. Omer, James A. Romesser, James M. Tepperman
  • Patent number: 4431736
    Abstract: Microbiological oxidation of biphenyl to bis-hydroxylated biphenyl employing Thamnostylum piriforme.
    Type: Grant
    Filed: June 1, 1982
    Date of Patent: February 14, 1984
    Assignee: E. I. Du Pont de Nemours and Company
    Inventor: James A. Romesser