Abstract: A method for recycling asphalt shingles is provided, where the method includes heating an asphalt shingle input from a first source in a mixing unit to melt the asphalt shingle input and produce a molten asphalt, directing the molten asphalt into a separation unit, separating the molten asphalt, at the separation unit, into solid materials and a fluid asphalt, and receiving and storing the fluid asphalt in a storage tank. A separation unit and a system for recycling asphalt shingles is also disclosed.

Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: An LCD display, comprising an active display area, a backlight to illuminate the active display area, and an LCD display stack. The LCD display stack may comprise a substrate, a liquid crystal layer over the substrate, and liquid crystal cover layer. The substrate, the liquid crystal layer, and the liquid crystal cover layer define a liquid crystal cell. The LCD display stack has an edge seal extending between the substrate and the liquid cover layer, and extends over the active display area and beyond the active display area to bend around an edge of the backlight, such that the edge seal lies beyond the active display area.

Abstract: This disclosure describes methods and devices that assist in forming biosensors. Specifically, features that align solutions containing molecules to be immobilized on biosensors. A retaining structure may be disposed at least partially around a target surface of a substrate. A resonating structure may be disposed on the target surface. A droplet of functionalized material may be disposed on the resonating structure and the target surface, which may be auto-aligned and retained by the retaining structure on the target surface to consistently cover the resonating structure.

Abstract: A disposable set of components for an organ perfusion system comprising a fluid supply duct for supplying fluid to the organ, a fluid removal duct for removing fluid from the organ, and a surrogate organ removably connected between the fluid supply duct and the fluid removal duct so as to form a fluid circuit, so that fluid can be circulated in the circuit in preparation for connection of the organ.

Abstract: This disclosure describes methods and devices that assist in forming biosensors. Specifically, features that align solutions containing molecules to be immobilized on biosensors. A retaining structure may be disposed at least partially around a target surface of a substrate. A resonating structure may be disposed on the target surface. A droplet of functionalized material may be disposed on the resonating structure and the target surface, which may be auto-aligned and retained by the retaining structure on the target surface to consistently cover the resonating structure.

Abstract: Computer-implemented methods and systems are provided for automatically performing a task on a remote computer. During a registration stage, the system receives personal information of a human user, obtains an IP address and a device configuration for a computing device, and stores the personal information, IP address, and the device configuration in record in a database. The system receives a request to interact with a remote website to perform a task, the request including the personal information of the human user. The system then retrieves the record from the database using the personal information. The system creates a virtual machine based on the device configuration for the computing device, selects one of a geographically distributed set of proxy servers having an IP geographically address resembling the IP address for the computing device, and executes instructions causing the virtual machine to interact with the remote website using the proxy server to perform the task.

Abstract: A device that includes a first portion, the first portion including at least one fluid channel; a fluid actuator; and an introducer, a second portion, the second portion including at least one well, the well containing at least one material, wherein one of the first or second portion is moveable with respect to the other, wherein the introducer is configured to obtain at least a portion of the material from the at least one well and deliver it to the fluid channel, and wherein the fluid actuator is configured to move at least a portion of the material in the fluid channel.

Abstract: This document relates to methods and materials for virotherapy. For example, this document provides methods and materials for treating cancer using a recombinant mumps virus as an oncolytic agent.

Abstract: Provided herein are methods of administering a KRAS G12C inhibitor to a cancer subject.

Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, vesicular stomatitis viruses, nucleic acid molecules encoding VSV polypeptides, methods for making vesicular stomatitis viruses, and methods for using vesicular stomatitis viruses to treat cancer are provided.

Abstract: A server-implemented method is disclosed. The method includes: receiving a request from an IP Multimedia Subsystem (IMS) network node of an IMS network; and in response to receiving the request, providing NAS registration state information associated with a user equipment (UE) to the IMS network node, the NAS registration state information indicating at least one of fourth-generation (4G) single radio voice call continuity (SRVCC) capability of the UE or fifth-generation (5G) SRVCC capability of the UE that is applicable when using an access network supported by a core network, wherein the server is configured to store separate instances of UE SRVCC capabilities, the separate instances including indications of at least one of 4G UE SRVCC capability or 5G UE SRVCC capability that is applicable when using the access network supported by the core network, and wherein the UE is registered with the IMS network using a session initiation protocol (SIP) via the access network.

Abstract: This document relates to methods and materials involved in treating cancer. For example, methods and materials for using one or more oncolytic viruses (e.g., one or more replicating oncolytic viruses) to treat cancer in a mammal (e.g., a human) identified as having a cancer likely to respond to oncolytic virotherapy are provided.

Abstract: The present invention provides combination therapy that includes an KRASG12C inhibitor, such as or a pharmaceutically acceptable salt thereof, and one or more additional pharmaceutically active agents, particularly for the treatment of cancers. The invention also relates to pharmaceutical compositions that contain an KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers.

Abstract: A location awareness system including a communication network, and a network operating element coupled to the communication network. At least one anchor network gateway is coupled to the communication network, the at least one anchor network gateway configured to generate a wireless anchor network. A plurality of anchors are configured to couple to one of the at least one anchor network gateway via its respective wireless anchor network. A plurality of tags is each configured to communicate with at least one anchor to provide ranging information for determination of a position of the tag within an area covered by the system.

Abstract: This document provides methods and materials related to CDV H and/or CDV F polypeptides. For example, CDV H polypeptides, CDV F polypeptides, recombinant viruses (e.g., vesicular stomatitis viruses (VSVs)) containing CDV H polypeptides and/or CDV F polypeptides, nucleic acid molecules encoding a CDV H polypeptide and/or CDV F polypeptide, methods for making recombinant viruses (e.g., VSVs) containing CDV H polypeptides and/or CDV F polypeptides, and methods for using recombinant viruses (e.g., VSVs) containing CDV H polypeptides and/or CDV F polypeptides to treat cancer or infectious diseases are provided.

Abstract: An injection setup kit can include a manifold connector, a first packaging container, and a fluid line. The first packaging container can define a first closed interior volume that includes a patient interface connector having a patient interface inlet, a first patient interface outlet, and a valve configured to selectively permit fluid communication through the patient interface connector. The patient interface inlet can be fluidly connected to the manifold outlet. The fluid line can have a first fluid line end and a second fluid line end. The first fluid line end can be connected to the patient interface inlet within the first closed interior volume. The second fluid line end can extend outside of the first closed interior volume and be connected to a manifold outlet outside of the first closed interior volume.

Abstract: A scaffolding assembly adapted to be releasably attached to an elongate support member such as an overhead pipe. The scaffolding assembly has a split collar and a platform assembly adapted to be releasably attached to the split collar. The split collar comprises at least two segments which can encircle the pipe and be secured to one another. The platform assembly which includes a platform deck has a connector formation which extends laterally outwardly from the deck to an extent that it can engage a receiving formation on the collar assembly and thereby attach the platform assembly to the collar assembly.

Abstract: A communication system and method for supporting a plurality of vehicle-to-everything radio access technologies (V2X RATs) is provided. The communication system configured to support multiple V2X RATs transmits, using a first V2X RAT, an indication of its availability to support an interworking function between the plurality of V2X RATs. The communication system receives an instruction to provide the interworking function between different V2X RATs. The interworking function may be incorporated in a vehicle that is joined to a platoon configured to use a first V2X RAT, and provide the interworking function between the first and a second V2X RAT. The interworking function may be used to add further vehicles to the platoon that communicate using only the second V2X RAT.