Patents by Inventor James A. Salomon

James A. Salomon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10876119
    Abstract: The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing. The RNAi constructs may be, for instance, miRNA constructs that are miRNA modulators.
    Type: Grant
    Filed: June 28, 2018
    Date of Patent: December 29, 2020
    Assignee: Phio Pharmaceuticals Corp.
    Inventors: Anastasia Khvorova, William Salomon, Joanne Kamens, Dmitry Samarsky, Tod M. Woolf, James Cardia
  • Publication number: 20200362330
    Abstract: The present invention relates to isolated polypeptides having D-psicose 3-epimerase activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
    Type: Application
    Filed: August 30, 2018
    Publication date: November 19, 2020
    Applicant: Novozymes A/S
    Inventors: Xinyu Shen, Randall Scott Deinhammer, James Ron Huffman, Kendra Stallings, Tine Hoff, Jesper Salomon, Anne Goldbech Olsen
  • Patent number: 10815485
    Abstract: The present invention relates to RNAi constructs with improved tissue and cellular uptake characteristics and methods of use of these compounds in dermal applications.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: October 27, 2020
    Assignee: Phio Pharmaceuticals Corp.
    Inventors: Anastasia Khvorova, William Salomon, Joanne Kamens, Dmitry Samarsky, Tod M. Woolf, Pamela A. Pavco, James Cardia
  • Publication number: 20200290037
    Abstract: A cartridge device for analyzing a body liquid comprises a first member having a plurality of wells for performing assays, and a second member having a compartment for holding at least one disposable pipette tip.
    Type: Application
    Filed: September 2, 2018
    Publication date: September 17, 2020
    Applicant: MeMed Diagnostics Ltd.
    Inventors: Noga SALOMON, Hfir OVED, Yana KHALFIN, Omer KATZENELSON, Amir GELMAN, Moran BROUK RUDICH, Roy NAVON, Assaf COHEN-DOTAN, Eran EDEN, Salit TZABAN, Arnon ZANGVIL, Ofer HALBREICH, Matthew FENWICK, Adrian Charles la SCOTT-MURPHY, Matthew YEUNG, James William LUTHER, Barbara TORNAGHI, Andrea BESANA, Thomas Sanelli CRUGNALE
  • Patent number: 10774330
    Abstract: The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: September 15, 2020
    Assignee: Phio Pharmaceuticals Corp.
    Inventors: Anastasia Khvorova, William Salomon, Joanne Kamens, Dmitry Samarsky, Tod M. Woolf, James Cardia
  • Patent number: 10662430
    Abstract: The present invention relates to ocular administration of sd-rxRNA and rxRNAori molecules.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: May 26, 2020
    Assignee: Phio Pharmaceuticals Corp.
    Inventors: Lyn Libertine, Anastasia Khvorova, William Salomon, Joanne Kamens, Dmitry Samarsky, Tod M. Woolf, James Cardia, Pamela A. Pavco
  • Patent number: 10613010
    Abstract: An embodiment includes an inertial torque device (ITD) for calibrating a viscometer. The ITD comprises a body, a coupling for connecting the body to a viscometer measurement interface, a rotatable inertial load device coupled to the body, an electric motor coupled to the rotatable inertial load device and coupled to the body, and a controller configured to calibrate the viscometer by controlling the electric motor to rotate the rotatable inertial load device at a predetermined acceleration to apply a predetermined torque to the coupling connected to the viscometer.
    Type: Grant
    Filed: December 6, 2017
    Date of Patent: April 7, 2020
    Assignee: Ametek, Inc.
    Inventors: James A. Salomon, Mark Genovese
  • Publication number: 20200002701
    Abstract: The present invention relates to methods for in vivo administration of sd-rxRNA molecules.
    Type: Application
    Filed: February 7, 2019
    Publication date: January 2, 2020
    Applicant: Phio Pharmaceuticals Corp.
    Inventors: Anastasia Khvorova, William Salomon, Joanne Kamens, Dmitry Samarsky, Tod M. Woolf, James Cardia
  • Publication number: 20190233826
    Abstract: The present invention relates to ocular administration of sd-rxRNA and rxRNAori molecules.
    Type: Application
    Filed: November 30, 2018
    Publication date: August 1, 2019
    Applicant: Phio Pharmaceuticals Corp.
    Inventors: Lyn Libertine, Anastasia Khvorova, William Salomon, Joanne Kamens, Dmitry Samarsky, Tod M. Woolf, James Cardia, Pamela A. Pavco
  • Publication number: 20190170628
    Abstract: An embodiment includes an inertial torque device (ITD) for calibrating a viscometer. The ITD comprises a body, a coupling for connecting the body to a viscometer measurement interface, a rotatable inertial load device coupled to the body, an electric motor coupled to the rotatable inertial load device and coupled to the body, and a controller configured to calibrate the viscometer by controlling the electric motor to rotate the rotatable inertial load device at a predetermined acceleration to apply a predetermined torque to the coupling connected to the viscometer.
    Type: Application
    Filed: December 6, 2017
    Publication date: June 6, 2019
    Inventors: James A. Salomon, Mark Genovese
  • Publication number: 20190161757
    Abstract: The present invention relates to RNAi constructs with minimal double-stranded regions, and their use in gene silencing. RNAi constructs associated with the invention include a double stranded region of 8-14 nucleotides and a variety of chemical modifications, and are highly effective in gene silencing. The RNAi constructs may be, for instance, miRNA constructs that are miRNA modulators.
    Type: Application
    Filed: June 28, 2018
    Publication date: May 30, 2019
    Applicant: RXi Pharmaceuticals Corporation
    Inventors: Anastasia Khvorova, William Salomon, Joanne Kamens, Dmitry Samarsky, Tod M. Woolf, James Cardia
  • Publication number: 20140311226
    Abstract: A rheometer instrument with radiant heating of sample fluid with use of emissive/absorbing spaced surfaces of a sample container and an interior surface and of a chamber surrounding the sample container in part that is in a heating unit and controls for reliably reaching and maintaining target sample temperatures. The sample fluid can be pressurized.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 23, 2014
    Applicant: Brookfield Engineering Laboratories, Inc.
    Inventors: Christopher J Murray, James A Salomon
  • Publication number: 20140290346
    Abstract: The present disclosure provides a viscometer or a rheometer including a touch screen interface. The touch screen interface enables a wider variety of user interface options and functions that would otherwise be cumbersome to implement. These options and functions include a wide variety of settings, security features, and the ability to manipulate test definitions and test data.
    Type: Application
    Filed: March 14, 2014
    Publication date: October 2, 2014
    Inventors: James A. Salomon, Alex H. Mak, Robert P. Bishop, Charles J. Falzarano, Teresa L. McKim, Jason P. Hartshorn, David A. DiCorpo
  • Patent number: 8449108
    Abstract: Systems and methods for providing evidence of printing in metering systems even in the event of a print head failure are provided. Along with generating a primary image for an indicium that evidences payment, a secondary image for the indicium, identical to a corresponding portion of the primary image but at a lower density, with physical boundaries that are within the boundaries of the primary image, is also generated. The primary image is printed by a first nozzle array, and the secondary image is printed by a second nozzle array. Because the primary image completely overlaps the secondary image, the secondary image is undetectable if the primary image is properly printed. The secondary image provides evidence of printing of the indicium that can be used to obtain a refund for the indicium in the event that the primary image was not printed due to failure of the first nozzle array.
    Type: Grant
    Filed: December 30, 2008
    Date of Patent: May 28, 2013
    Assignee: Pitney Bowes Inc.
    Inventors: John P. Miller, David J. Eaton, Peter T. Collings, Lun Chan, Easwaran Nambudiri, James A. Salomon
  • Patent number: 8335748
    Abstract: A mailing machine for the creation of mailpieces includes a print station and a transport system for passing a length of the label material through the print station to receive information on a face surface of the label material. A processor is adapted to store rating information based upon the weight and dimensions of the mailpiece and is operatively coupled to, and controls, the print station and transport system. In a first operating mode, the processor prints rating information on a length of label material, and in a second operating mode, the processor prints postage indicia on the face surface of the label material based upon the rating information for subsequent application to a mailpiece. In the second operating mode, the postage indicia may optionally be printed on the label material or directly on the face surface of the mailpiece envelope.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: December 18, 2012
    Assignee: Pitney Bowes Inc.
    Inventors: James A. Salomon, Christopher M. Giles
  • Publication number: 20110295769
    Abstract: A mailing machine for the creation of mailpieces includes a print station and a transport system for passing a length of the label material through the print station to receive information on a face surface of the label material. A processor is adapted to store rating information based upon the weight and dimensions of the mailpiece and is operatively coupled to, and controls, the print station and transport system. In a first operating mode, the processor prints rating information on a length of label material, and in a second operating mode, the processor prints postage indicia on the face surface of the label material based upon the rating information for subsequent application to a mailpiece. In the second operating mode, the postage indicia may optionally be printed on the label material or directly on the face surface of the mailpiece envelope.
    Type: Application
    Filed: June 1, 2010
    Publication date: December 1, 2011
    Applicant: Pitney Bowes Inc.
    Inventors: James A. SALOMON, Christopher M. Giles
  • Patent number: 8052147
    Abstract: An inserter system includes a pre-fold accumulator subsystem in which plural sheets are collected before folding and insertion into an envelope. A divert gate is at the upstream side of the pre-fold accumulator to selectively downwardly divert sheets fed in a reverse direction from the pre-fold accumulator. Positioning of the divert gate is controlled by a mechanism that couples the divert gate and a drive shaft that drives a sheet drive belt component of the pre-fold accumulator.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: November 8, 2011
    Assignee: Pitney Bowes Inc.
    Inventors: James A. Salomon, Norman R. Lilly, Aaron D. Smith
  • Patent number: D786279
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 9, 2017
    Assignee: Brookfield Engineering Laboratories, Inc.
    Inventors: Teresa L. McKim, James A. Salomon, Alex H. Mak, Robert P. Bishop, Charles J. Falzarano
  • Patent number: D888267
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: June 23, 2020
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Noga Salomon, Kfir Oved, Roy Navon, Assaf Cohen-Dotan, Eran Eden, Salit Tzaban, Yana Khalfin, Ofer Halbreich, Matthew Fenwick, Adrian Charles Ian Scott-Murphy, Matthew Hou-Pou Yeung, James William Luther, Barbara Tornaghi, Andrea Besana
  • Patent number: D888269
    Type: Grant
    Filed: September 2, 2018
    Date of Patent: June 23, 2020
    Assignee: MeMed Diagnostics Ltd.
    Inventors: Noga Salomon, Kfir Oved, Omer Nahum Katzenelson, Eran Eden, Matthew Hou Pou Yeung, James William Luther, Barbara Tornaghi, Andrea Besana