Abstract: A liquid controlling surface, comprising a formation comprising a plurality of individual open topped, closed bottomed cells for containing liquid with each of the cells having a cell wall integral with the closed bottom and defining a well. Each of the cell walls have a top edge. The surface also includes a plurality of distribution channels extending between adjacent cells and being positioned on the cell wall at a height to permit liquid to drain to the adjacent cell when a cell liquid level exceeds a predetermined limit and to permit liquid to be retained in the well up to the limit. At least some of the cell walls are sized and shaped to define contact areas at the top edges to support an object above the limit.

Abstract: An accurate blending system for blending a feed liquid and first and second adjusting liquids includes a first feed means adapted to communicate with a supply of feed liquid, a second feed means adapted to communicate with a supply of the first adjusting liquid and a third feed means adapted to communicate with a supply of the second adjusting liquid. The first, second and third feed means may be pumps, valves or combinations thereof. A mixing device is in communication with the first, second and third feed means. First and second sensors are in communication with the mixing device. A controller communicates with the first and second sensors so that first and second characteristics of the solution in the mixing device can be detected. The controller also communicates with the first and second feed means so that delivery of first and second adjusting liquid to the mixing device can be controlled based upon the detected first and second characteristics of the solution in the mixing device.

Abstract: A liquid controlling surface, comprising a formation comprising a plurality of individual open topped, closed bottomed cells for containing liquid with each of the cells having a cell wall integral with the closed bottom and defining a well. Each of the cell walls have a top edge. The surface also includes a plurality of distribution channels extending between adjacent cells and being positioned on the cell wall at a height to permit liquid to drain to the adjacent cell when a cell liquid level exceeds a predetermined limit and to permit liquid to be retained in the well up to the limit. At least some of the cell walls are sized and shaped to define contact areas at the top edges to support an object above the limit.

Abstract: A liquid-controlling surface, comprising a formation comprising a plurality of individual open topped, closed bottomed cells for containing liquid, each of the cells having a cell wall integral with the closed bottom and defining a well; a plurality of distribution channels extending between adjacent cells and being position on the cell wall at a height to permit liquid to drain to the adjacent cell when a cell liquid level exceeds a predetermined limit and to permit liquid to be retained in the well up to the limit; and a perimeter wall surrounding the cells. The perimeter wall having a height higher than the distribution channels to prevent liquid from leaking from the cells to an area outside the perimeter, and where the formation and perimeter wall comprise rubber.

Abstract: A liquid-controlling surface, comprising a formation comprising a plurality of individual open topped, closed bottomed cells for containing liquid, each of the cells having a cell wall integral with the closed bottom and defining a well; a plurality of distribution channels extending between adjacent cells and being position on the cell wall at a height to permit liquid to drain to the adjacent cell when a cell liquid level exceeds a predetermined limit and to permit liquid to be retained in the well up to the limit; and a perimeter wall surrounding the cells. The perimeter wall having a height higher than the distribution channels to prevent liquid from leaking from the cells to an area outside the perimeter, and where the formation and perimeter wall comprise rubber.

Abstract: A liquid-controlling surface, comprising a formation comprising a plurality of individual cells for containing liquid, each of said cells having a cell wall; a plurality of distribution channels, one connecting each cell to each adjacent cell, each distribution channel being positioned on the internal cell wall at a height so as to channel liquid to the adjacent cell when a cell liquid level exceeds a predetermined limit; a perimeter wall for preventing liquid from leaking to an area outside the wall.

Abstract: An accurate blending module for adjusting the pH of solutions containing therapeutic proteins includes a recirculation loop that receives the therapeutic protein solution via a feed pump and an acid solution via an adjusting pump. The recirculation loop includes a recirculation pump and a pH sensor that detects the pH of the solution in the recirculation loop. A controller communicates with the pH sensor and the adjusting pump. The adjusting pump adds acid to the recirculation loop based on the pH readings taken by the pH sensor. The recirculation pump recirculates the therapeutic protein solution and acid in the recirculation loop so that it is mixed. As a result, the pH of the therapeutic protein solution is precisely controlled and adjusted in a non-destructive fashion.

Abstract: An accurate blending system for blending a feed liquid and first and second adjusting liquids includes a first feed means adapted to communicate with a supply of feed liquid, a second feed means adapted to communicate with a supply of the first adjusting liquid and a third feed means adapted to communicate with a supply of the second adjusting liquid. The first, second and third feed means may be pumps, valves or combinations thereof. A mixing device is in communication with the first, second and third feed means. First and second sensors are in communication with the mixing device. A controller communicates with the first and second sensors so that first and second characteristics of the solution in the mixing device can be detected. The controller also communicates with the first and second feed means so that delivery of first and second adjusting liquid to the mixing device can be controlled based upon the detected first and second characteristics of the solution in the mixing device.

Abstract: A synthesizer system for use as either a freestanding or facility integrated device and a method of use. The system includes an inlet manifold of diaphragm valves that receives at least two liquid feeds. The streams flow either to a blending module or directly to a delivery module. From there they are delivered to a reactor for the sequential creation of desired compounds. For flow through solid phase synthesis added capability for feed recirculation and effluent detection with feedback control is included.

Abstract: An accurate blending module for retrofitting existing laboratory or industrial systems or use as a standalone device and a method of use. The module includes a proportioning submodule that receives and merges at least two liquid feeds. The merged stream flows to a blending submodule. The resulting blended liquid stream flows through a detection submodule which detects a characteristic of the blended liquid stream. The detection submodule sends a corresponding signal to a controller. The controller adjusts the proportioning submodule based on the signal.

Abstract: A liquid-controlling mat, comprising a formation comprising a plurality of individual cells for containing liquid, each of said cells having a cell wall; a plurality of distribution channels, one connecting each cell to each adjacent cell, each distribution channel being positioned on the internal cell wall at a height so as to channel liquid to the adjacent cell when a cell liquid level exceeds a predetermined limit; a perimeter wall for preventing liquid from leaking to an area outside the wall.

Abstract: An accurate blending module for adjusting the pH of solutions containing therapeutic proteins includes a recirculation loop that receives the therapeutic protein solution via a feed pump and an acid solution via an adjusting pump. The recirculation loop includes a recirculation pump and a pH sensor that detects the pH of the solution in the recirculation loop. A controller communicates with the pH sensor and the adjusting pump. The adjusting pump adds acid to the recirculation loop based on the pH readings taken by the pH sensor. The recirculation pump recirculates the therapeutic protein solution and acid in the recirculation loop so that it is mixed. As a result, the pH of the therapeutic protein solution is precisely controlled and adjusted in a non-destructive fashion.

Abstract: A prefabricated room module (1) is provided for use in the construction of a modular building. The room module comprises a floor slab (2) of generally rectangular shape in plan, and load bearing walls (3,4) formed at adjacent sides of the slab and mutually adjoining at a common corner (5). The module has no ceiling slab opposite the floor slab (2) and an open face opposite one of the load bearing walls (4) which constitutes a party wall. Opposite another of the load bearing walls (3) the module may be open or include a further wall (7) which can have an access opening (10) therein for providing service access to a kitchen or bathroom pod (9) installed in a corner of the module. Edges of the floor slab (2) have projecting tongues (11) and fastening means for engaging complementary recesses and fastening means respectively of an adjacent module. The module may have a ceiling slab instead of a floor slab (2).

Abstract: Methods, compounds, compositions and kits that relate to pretargeted delivery of diagnostic and therapeutic agents are disclosed. In particular, methods for radiometal labeling of biotin and for improved radiohalogenation of biotin, as well as related compounds, are described. Also, clearing agents, anti-ligand-targeting moiety conjugates, target cell retention enhancing moieties and additional methods are discussed.

Abstract: Method and apparatus for releasably attaching electronic components to a user's clothing. The apparatus enables an electronic component, for instance a tactical radio microphone, to be releasably attachable to a user's clothing by one of the buttons thereof. The apparatus defines a slot for engaging a wearer's button and a ring or other keeper device for receiving therein the clip of a microphone or other electronic component. The body of the apparatus is sized to minimize rotation of the microphone or other electronic device around the axis of its rotation formed by its clip and the wearer's garments.

Abstract: Conjugates of trichothecenes and agents that bind to a defined population of cells are disclosed. Preferred are conjugates of trichothecene molecules with polyclonal or monoclonal antibodies or fragments thereof that recognize antigens that are present only on tumor cells or are augmented in their expression on tumor cells as compared to normal tissues. Trichothecene molecules are coupled to the agent through non-covalent and covalent linkages, such as peptide bonds, disulfide bonds, thioester bonds, or thioether bonds. A method for inhibiting the growth and metabolism of antigen-positive cells is also disclosed. Derivatized trichothecene compounds prepared for conjugation to targeting agents are also disclosed.

Abstract: Novel labeling reagents are useful for radiolabeling proteins such as antibodies with radionuclide metals such as .sup.99m Tc, .sup.186 Re, and .sup.188 Re. The reagents are of the following formula: ##STR1## wherein: each X is independently chosen from O, S, NH, or NR.sub.2, wherein R.sub.2 is a protecting group or an electron withdrawing group;R.sub.1 represents a protecting group, wherein each R.sub.1 is a separate protecting group or the two R.sub.1 symbols are taken together to represent a single protecting group; andeach T is independently chosen from hydrogen, lower alkyl groups of from 1 to about 6 carbon atoms, electron withdrawing groups, and lower alkyl groups of from 1 to about 6 carbon atoms substituted with electron withdrawing group(s).

Abstract: Novel labeling reagents are useful for radiolabeling proteins such as antibodies with radionuclide metals such as .sup.99m Tc, .sup.186 Re, and .sup.188 Re. The reagents are of the following formula: ##STR1## wherein: each X is independently chosen from O, S, NH, or NR.sub.2, wherein R.sub.2 is a protecting group or an electron withdrawing group;R.sub.1 represents a protecting group, wherein each R.sub.1 is a separate protecting group or the two R.sub.1 symbols are taken together to represent a single protecting group; andeach T is independently chosen from hydrogen, lower alkyl groups of from 1 to about 6 carbon atoms, electron withdrawing groups, and lower alkyl groups of from 1 to about 6 carbon atoms substituted with electron withdrawing group(s).

Abstract: A device for separating molecular components from liquids. A multi-layer microporous membrane assembly is located within the housing (1) with edges of each membrane within the assembly lying adjacent to a barrier. Means (5,6) are provided for substantially preventing flow between the membrane edges and the barrier, so that flow is through the membranes in series. Inlet means (2) direct incoming liquid on to a first surface of the membrane assembly, and outlet means (3) gather and direct outgoing liquid from a second surface of the membrane assembly. The membrane material of the assembly has a ligand or an immobilized enzyme bound thereto for effecting chromatographic separation or an immobilized enzyme reaction.

Abstract: The invention relates to an improvement to an installation for preventing the ingress of super-cooled water, ice, snow and other debris as taught in U.S. Pat. No. 3,329,377. In the patent, an inertial separator effect is used to prevent ingress of super cooled water, ice, snow and other debris to an aircraft engine. The effect is obtained by an installation including a duct formed in a sub-nacelle of the engine to extend generally longitudinally of the engine. An air deflecting surface in the duct confines the incoming air to a passage of reduced cross section, and an opening in the duct wall downstream of the deflecting surface is formed between the trailing edge of the deflecting surface and the leading edge of a rearward portion of the duct, the opening in the duct wall communicating with the engine air intake. In accordance with the present invention, any or all of the following improvements are made to the above installation:A.