Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.

Abstract: A stabilizing process for tobacco and tobacco products includes sterilizing the tobacco by applying an electron beam treatment to the tobacco. The process may also include treating the tobacco. The treating the tobacco includes pre-conditioning the tobacco, pasteurizing the tobacco, curing the tobacco, fermenting the tobacco, or combinations thereof. The method may also include forming a smokeless tobacco product containing the tobacco.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: A top drive for engagement with a travelling block with a hook can include an airlift thread compensator connected to a bail. An enclosure can be connected to the bail with an airbag disposed therein. A bail pin can be engaged through the enclosure, and can be connected to the airbag. The airbag can support weight of the top drive. Upper links can be connected to the enclosure and to a top drive housing. The top drive housing can support a stem connected to a motor, and a bearing can be disposed about the stem. Lower links can be connected to the top drive housing and to an elevator for moving tubulars. An inside blow out preventer can be connected to the stem and to a saver sub. A torque wrench assembly can be connected to the top drive housing for gripping tubulars.

Abstract: A drilling rig with a top drive for engagement with a travelling block with a hook comprising an airlift thread compensator with an airlift box connected to a bail. The airlift box can have an airbag disposed therein. A bail pin can be engaged through the airlift box, and can be connected to the airbag. The airbag can support the top drive. Upper links can be connected to the airlift box and to a bearing housing. The bearing housing can support a stem connected to a motor, and a bearing can be disposed about the stem. Lower links can be connected to the bearing housing and to an elevator for moving tubulars. An inside blow out preventer can be connected to the stem and to a saver sub. A torque wrench can be connected to the bearing housing for gripping tubulars.

Abstract: A method for using a top drive is disclosed herein. The method can include: actuating a motor to provide power to the top drive, thereby rotating a stem with a saver sub mounted to a top drive housing having a bearing disposed about the rotatable stem; grabbing, lifting, and positioning tubulars using an elevator; and suspending weight of the top drive to prevent damage to threads of the tubulars during threadable engagement and disengagement of the tubulars using an airbag of an airlift thread compensator. The method can further include: positioning a torque wrench assembly along the tubulars for connecting the tubulars using a hydraulic cylinder disposed inside a torque supporting telescoping tubes; and movably positioning a single hollow cylinder rod of the hydraulic cylinder to extend into a first and second protected area, thereby preventing axial movement of a flexible hose during operation of the torque wrench assembly.

Abstract: Proteins from the genus Photorhabdus are toxic to insects upon exposure. Photorhabdus luminescens (formerly Xenorhabdus luminescens) have been found in mammalian clinical samples and as a bacterial symbiont of entomopathogenic nematodes of genus Heterohabditis. These protein toxins can be applied to, or genetically engineered into, insect larvae food and plants for insect control.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: A prosthesis can replace at least a portion of an anatomical wrist. The prosthesis can include modular portions and bone ingrowth portions for fixation. The modular prosthesis can include selected portions that are assembled for implantation.

Abstract: A prosthetic wrist can replace a portion of an anatomical wrist. A bone replacing portion can be provided that also includes an augment member to assist in fixation of the bone portion or the prosthesis to the bone. The various prosthesis embodiments can allow for a hemi- or total, or revision wrist arthroplasty. Modular portions can allow for intraopertative customization.

Abstract: A fuel line disconnection tool includes a handle member with a hand grip end and a slotted opposite head end adapted to receive generally mirror image flanged adapters having semi-yclindrical tubular projections which enable placement of the adapters in the slot at the head end of the handle. The adapters may then be fitted about a fuel line and the handle attached thereto and manipulated to disengage the connection mechanism between the fuel line and fuel filter.

Abstract: The invention features tobacco compositions and methods of their use and manufacture. Compositions of the invention may be based on a variety of technologies. Technologies include films, tabs, shaped parts, gels, consumable units, insoluble matrices, and hollow shapes. In addition to tobacco, compositions may also contain flavors, colors, and other additives as described herein. Compositions may also be orally disintegrable. Exemplary compositions and methods of their manufacture are described herein.

Abstract: Pharmaceutical compositions and methods for treating epithelial cancers and precancerous lesions employ indole carbazole compounds, such as staurosporine. Compositions containing these compounds are administered to a patient in an effective amount and may be administered topically.