Patents by Inventor James A. Trofatter

James A. Trofatter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tumor suppressor merlin and antibodies thereof
    Patent number: 6077685
    Abstract: A novel tumor suppressor protein, merlin, is described, including DNA sequences encoding merlin, and recombinant vectors and hosts capable of expressing merlin. Method for the diagnosis and treatment of merlin-associated tumors, and for the diagnosis and treatment of the disease neurofibromatosis 2 (NF2) are also provided.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 20, 2000
    Assignee: The General Hospital Corporation
    Inventors: James A. Trofatter, Mia M. MacCollin, James F. Gusella
  • Tumor suppressor gene merlin
    Patent number: 5707863
    Abstract: A novel tumor suppressor protein, merlin, is described, including DNA sequences encoding merlin, and recombinant vectors and hosts capable of expressing merlin. Method for the diagnosis and treatment of merlin-associated tumors, and for the diagnosis and treatment of the disease neurofibromatosis 2 (NF2) are also provided.
    Type: Grant
    Filed: December 22, 1993
    Date of Patent: January 13, 1998
    Assignee: General Hospital Corporation
    Inventors: James A. Trofatter, Mia M. MacCollin, James F. Gusella