Patents by Inventor James A. Turpin

James A. Turpin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thiolesters and uses thereof
    Patent number: 7625917
    Abstract: This invention pertains to the discovery of a novel family of thiolesters and uses thereof. Also provided for are viricidal compounds and pharmaceutical formulations comprising these novel thiolesters. The invention also provides thiolester-inactivated viruses and thiolester-complexed viral proteins.
    Type: Grant
    Filed: December 16, 2003
    Date of Patent: December 1, 2009
    Inventors: James A. Turpin, Yongsheng Song, Ettore Appella, John K. Inman, David G. Covell, William G. Rice, Anders Wallqvist, Andrew Maynard, Mingjun Huang
  • Thiolesters and uses thereof
    Publication number: 20040132785
    Abstract: This invention pertains to the discovery of a novel family of thiolesters and uses thereof. Also provided for are viricidal compounds and pharmaceutical formulations comprising these novel thiolesters. The invention also provides thiolester-inactivated viruses and thiolester-complexed viral proteins.
    Type: Application
    Filed: December 16, 2003
    Publication date: July 8, 2004
    Applicant: The Government of the U. S.of America as Represented by The Sec. of Health and Human Svc.
    Inventors: James A. Turpin, Yongsheng Song, Ettore Appella, John K. Inman, David G. Covell, William G. Rice, Anders Wallqvist, Andrew Maynard, Mingjun Huang
  • Thiolesters and uses thereof
    Patent number: 6706729
    Abstract: This invention pertains to the discovery of a novel family of thiolesters and uses thereof. Also provided for are viricidal compounds and pharmaceutical formulations comprising these novel thiolesters. The invention also provides thiolester-inactivated viruses and thiolester-complexed viral proteins.
    Type: Grant
    Filed: May 16, 2001
    Date of Patent: March 16, 2004
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: James A. Turpin, Yongsheng Song, Ettore Appella, John K. Inman, David G. Covell, William G. Rice, Anders Wallqvist, Andrew Maynard, Mingjun Huang
  • Acridone-derived compounds useful as antineoplastic and antiretroviral agents
    Patent number: 6541483
    Abstract: The present invention relates to several novel acridone-derived compounds of of formula (I) or (II). These compounds are potent anti-viral agents, useful in the treatment of viral diseases, such as Human Immunodeficiency Virus. In addition, these compounds are anti-neoplastic agents useful in the treatment of various forms of cancer. wherein R1 and R2 are independently —H, —OH, amino, alkylamino, dialkylamino, alkoxy, alkyl, haloalkyl or halogen; n is 2 to 6, X and X′ are independently —N or —NO2; Y and Y′ are independently —N or —CH, or —H; and the double-slash represents a double bond or no bond.
    Type: Grant
    Filed: January 15, 2001
    Date of Patent: April 1, 2003
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Christopher J. Michejda, Marek W. Cholody, William G. Rice, James A. Turpin
  • Acridone-derived compounds useful as antineoplastic and antiretroviral agents
    Publication number: 20010009914
    Abstract: The present invention relates to several novel acridone-derived compounds of of formula (I) or (II). These compounds are potent anti-viral agents, useful in the treatment of viral diseases, such as Human Immunodeficiency Virus. In addition, these compounds are anti-neoplastic agents useful in the treatment of various forms of cancer.
    Type: Application
    Filed: January 15, 2001
    Publication date: July 26, 2001
    Inventors: Christopher J. Michejda, Marek W. Cholody, William G. Rice, James A. Turpin
  • Acridone-derived compounds useful as antineoplastic and antiretroviral agents
    Patent number: 6187775
    Abstract: The present invention relates to several novel acridone-derived compounds of of formula (I) or (II). These compounds are potent anti-viral agents, useful in the treatment of viral diseases, such as Human Immunodeficiency Virus. In addition, these compounds are anti-neoplastic agents useful in the treatment of various forms of cancer. wherein R1 and R2 are independently —H, —OH, amino, alkylamino, dialkylamino, alkoxy, alkyl, haloalkyl or halogen; n is 2 to 6, X and X′ are independently —N or —NO2; Y and Y′ are independently —N or —CH, or —H; and the double-slash represents a double bond or no bond.
    Type: Grant
    Filed: September 22, 1998
    Date of Patent: February 13, 2001
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Christopher J. Michejda, Marek W. Cholody, William G. Rice, James A. Turpin