Abstract: A microfluidic device performs a method of partitioning droplets from a fluid reservoir containing particles that provides a non-Poissonian distribution of dispensed droplets containing a desired number of particles. Using an electrowetting on dielectric (EWOD) device, droplets are dispensed having a Poissonian distribution of dispensed droplets containing a desired number of particles, and the droplets are interrogated to determine whether each dispensed droplet has a desired number of particles. Droplets that contain the desired number of particles are moved by EWOD operation to a reaction area on the EWOD device, and droplets that do not contain the desired number of particles are rejected and moved by EWOD operation to a holding area on the EWOD device that is different and spaced apart from the reaction area. The result is that droplets in the reaction area have a non-Poissonian distribution of droplets containing the desired number of particles.

Abstract: Described herein are devices and methods for mitral valve repair. The devices and methods implant a plurality of distal anchors at an annulus of the mitral valve (e.g., the posterior annulus) and tension artificial chordae to pull the portion of the annulus toward an opposite edge and inward into the ventricle. This can effectively reduce the size of the orifice and increase coaptation. The delivery devices can be configured to be actuated to form a distal anchor made of a pre-formed knot. The delivery devices deliver the pre-formed knot in an elongate configuration. Actuation of the delivery device causes the pre-formed knot to transition from the elongate configuration to the deployed configuration by approximating opposite ends of a suture coupled to a coiled configuration to form one or more loops. After formation of the knot, the delivery device can be withdrawn.

Abstract: Arrangements for providing context aware response functions are provided. In some examples, sensor data may be received from a plurality of sensors in a sensor data farm associated with an enterprise organization. The sensor data may be received from various types of sensors and/or from sensors from various vendors or manufacturers. a machine learning model may be executed to analyze the sensor data. Based on an output of the machine learning model, a determination may be made as to whether one or more enterprise-specific thresholds have been met or exceeded. If not, additional, subsequently received data may be analyzed. If so, one or more notifications or notification actions may be identified. In some examples, the notification or notification actions may be executed and response data may be received. The response data may be used to update and/or validate the machine learning model.

Abstract: Described herein are methods and apparatus for approximating targeted tissue using locking sutures. The locking sutures can be configured to receive suture ends that are interweaved through portions of the locking sutures. In a pre-deployment configuration, a locking suture can slide along suture tails and can be positioned at a target location within a target region. Once a desired position and/or tension is achieved, the locking suture can be transitioned to a post-deployment configuration where the locking suture constricts around the suture tails to inhibit relative movement between the suture tails and the locking suture. A visualization system can be used to provide visual feedback with respect to approximating the targeted tissue and the locking sutures.

Abstract: Arrangements for sensor data normalization and analysis are provided. In some arrangements, first sensor data may be received from a first sensor of a first sensor type. The first sensor may be associated with a first vendor and may output data in a first format unique to the first vendor. Second sensor data may be received from a second sensor. The second sensor may be a second sensor type. The second sensor may be associated with a second vendor and may output data in a second format unique to the second vendor. The first and second sensor data may be normalized from the first format and second format to a uniform format unique to an enterprise organization. The formatted data may be compared to one or more enterprise-specific thresholds. If one or more thresholds have been met or exceeded, a notification may be generated and transmitted to a computing device.

Abstract: Suspensions of magneto-responsive Janus colloids form chains and undergo alignment under the influence of a magnetic field. When the magnetic field is aligned with a light path, light transmission through the sample increases as compared to randomly or orthogonally oriented chains. The emissivity response of this suspension is presented as a function of particle concentration and magnetic field strength. A variation of the Beer-Lambert model and ray-tracing simulations capture the behavior of the experimentally measured difference in intensity between magnetically activated and non-activated Brownian suspensions. Experiments demonstrate up to 25% contrast in transmission of visible light, which may be further optimized through materials selection. Similar experiments when these Janus particle chains are suspended in carbon tetrachloride, demonstrate an emissivity variation in the near infrared of ˜10%.

Abstract: Methods of sealing tubulars are disclosed herein, which methods may include: providing a patch plug assembly that includes: a shaft; a wedge coupled to the shaft; a slip coupled to the shaft; a plug slidably coupled to the wedge; and a ferrule disposed between the wedge and the plug; pushing the slip against the tubular; pushing the plug against the ferrule after the slip is pushed against the tubular; pushing the ferrule against the wedge after the plug is pushed against the ferrule; and pushing a plug portion of the plug against an inner surface of the tubular.

Abstract: A system for predicting and summarizing medical events from electronic health records includes a computer memory storing aggregated electronic health records from a multitude of patients of diverse age, health conditions, and demographics including medications, laboratory values, diagnoses, vital signs, and medical notes. The aggregated electronic health records are converted into a single standardized data structure format and ordered arrangement per patient, e.g., into a chronological order. A computer (or computer system) executes one or more deep learning models trained on the aggregated health records to predict one or more future clinical events and summarize pertinent past medical events related to the predicted events on an input electronic health record of a patient having the standardized data structure format and ordered into a chronological order.

Abstract: A boxed battery dispenser configured to hold a plurality of battery trays. Each battery tray of the plurality of battery trays is configured to hold a plurality of batteries, and each battery tray can be independently removeable from the dispenser.

Abstract: A sensor for a flexible sensor assembly includes a drive coil, a first set of sensing coils, a second set of sensing coils, and a configuration for sensing for discontinuities in a structure desired to be sensed. A method of operating the sensor can include positioning the sensor proximate to the structure, energizing the drive coil, and sensing eddy currents with the sensing coils.

Abstract: A speaker can have a main body with a generally spheroidal shape, which can be supported standing on its end. The speaker can include a subwoofer that faces forward. A plurality of mid-range drivers can be distributed around the sub-woofer, facing generally forward and radially outward. A plurality of tweeters can be distributed around the sub-woofer, facing generally forward and generally outward. The outer housing portion of the speaker can be covered with a fabric material. A user interface ring 162 can be touch sensitive to receive input, and can have a plurality of lights that can be illuminated separately to convey information to the user.

Abstract: Embodiments of the disclosure are drawn to apparatuses and methods for a rotating optical reflector. Optical systems may have a limited field of view, and so in order to expand the area that the optical system collects data from, the field of view of the optical system may be scanned across a target area. The present disclosure is directed to a rotating optical reflector, which includes a transmissive layer which refracts light onto a reflective layer, which has a normal which is not parallel to the axis about which the optical reflector is rotated. The optical reflector may be both statically and dynamically balanced, which may allow an increased size of the optical reflector, which in turn may increase the aperture of an optical system (e.g., a lidar system) using the rotating optical reflector.

Abstract: The invention provides nucleic acid therapeutics and methods for using these nucleic acid therapeutics in the treatment of complement-related disorders.

Abstract: Devices, systems, and methods of the present disclosure are generally directed to facilitating user control of high-pressure flow of liquid for oral irrigation carried out as part of personal dental care. Such control over high-pressure flow may reduce the likelihood of errant spray of liquid outside of the user's mouth (e.g., onto mirrors, countertop surfaces, or the user's clothes). Such improved control over errant spraying may reduce the potential for frustration and, thus, may promote maintaining oral irrigation as part of a personal dental care routine. Further, or instead, through facilitating user control of high-pressure flow of liquid, the devices, systems, and methods of the present disclosure may improve the effectiveness and efficiency of self-administered oral irrigation in promoting a user's oral hygiene.

Abstract: A system is provided for dynamically modifying a timeline recipe for targeted content delivery. The system includes a content consumption profiler configured to receive viewer profile data relating to a plurality of content consumption devices and to dynamically update a viewer profile database that stores classification parameters for each of the plurality of content consumption devices based on the viewer profile data. The system also includes a user interface generator configured to generate a user interface for dynamically modifying at least one timeline recipe for a targeted content delivery to at least one of the plurality of content consumption devices. Moreover, the system includes a content rendered and delivery manager configured to generate a media content production to be displayed on the respective content consumption devices of targeted grouping based on receiving input via the generated user interface.

Abstract: A boxed battery dispenser configured to hold a plurality of battery trays. Each battery tray of the plurality of battery trays is configured to hold a plurality of batteries, and each battery tray can be independently removeable from the dispenser.

Abstract: A method performed by an electronic device is described. The method includes obtaining a first image from a first camera, the first camera having a first focal length and a first field of view. The method also includes obtaining a second image from a second camera, the second camera having a second focal length and a second field of view disposed within the first field of view. The method further includes aligning at least a portion of the first image and at least a portion of the second image to produce aligned images. The method additionally includes fusing the aligned images based on a diffusion kernel to produce a fused image. The diffusion kernel indicates a threshold level over a gray level range. The method also includes outputting the fused image. The method may be performed for each of a plurality of frames of a video feed.

Abstract: A theft detection system includes a sensor having a magnetic ball axially moveably supported within an axial opening in the spool having an electrical coil wound around the spool such that movement of the ball creates electrical signals in the coil. A housing is configured to support and vibrationally couple the sensor to a vehicle exhaust system. A circuit is coupled to the electrical coil to receive the electrical signals and generate an alarm signal in response to movement of the ball being indicative of vibration of the exhaust system resulting from exhaust system tampering.

Abstract: Methods of sealing tubulars are disclosed herein, which methods may include: providing a patch plug assembly that includes: a shaft; a wedge coupled to the shaft; a slip coupled to the shaft; a plug slidably coupled to the wedge; and a ferrule disposed between the wedge and the plug; pushing the slip against the tubular; pushing the plug against the ferrule after the slip is pushed against the tubular; pushing the ferrule against the wedge after the plug is pushed against the ferrule; and pushing a plug portion of the plug against an inner surface of the tubular.

Abstract: An edge wear protector system adapted to be attached to a plate of a bucket is provided. Edge wear protector system includes a first side member having a proximal end and a distal end opposite the proximal end, the first side member adapted to be attached to one side of the plate, a second side member having a near end and a far end opposite the near end, the second side member adapted to be attached to another side of the plate, the another side of the plate being opposite the one side of the plate, an end member adapted to be attached to an edge of the plate, the edge of the plate extends from the one side to the another side of the plate, such that the first side member is attachable to the end member via its proximal end and the second side member is attachable to the end member via the near end.