Abstract: A patient support apparatus includes a cushion, a cover arranged over a top side of the cushion, and a sensor unit. The sensor unit is coupled to the cover and arranged to underlie a patient supported on the cover. The sensor unit includes a sensor configured to detect conditions near the interface of a patient's skin with the cover.

Abstract: A relatively compact implantable medical device includes a fixation member formed by a plurality of fingers mounted around a perimeter of a distal end of a housing of the device; each finger is elastically deformable from a relaxed condition to an extended condition, to accommodate delivery of the device to a target implant site, and from the relaxed condition to a compressed condition, to accommodate wedging of the fingers between opposing tissue surfaces at the target implant site, wherein the compressed fingers hold a cardiac pacing electrode of the device in intimate tissue contact for the delivery of pacing stimulation to the site. Each fixation finger is preferably configured to prevent penetration thereof within the tissue when the fingers are compressed and wedged between the opposing tissue surfaces. The pacing electrode may be mounted on a pacing extension, which extends distally from the distal end of the device housing.

Abstract: Embodiments of the present disclosure include a system, method, and apparatus comprising a direct steam generator configured to generate saturated steam and combustion exhaust constituents.

Abstract: A fenestration system includes one or more of a light modulation controller or ventilation modulation controller. The light modulation controller is in communication with at least one light modulation element of a fenestration assembly having a frame and a panel. The light modulation controller includes a light prescription module configured to provide a specified light prescription for the building interior. A lighting difference module is configured to determine a prescription difference between the specified light prescription and ambient light. A dynamic light module of the light modulation controller operates the at least one light modulation element according to the prescription difference. The ventilation modulation controller is in communication with at least one operator configured to open and close the panel.

Abstract: An approach is disclosed herein for balancing layer densities in using an automated process. The approach disclosed herein operates on a region-by-region and layer-by-layer basis to perform parameterized layer balancing. In some embodiments, the process comprises determining densities of respective layers in respective regions, evaluating each layer and region to determine whether operations need to be taken to balance those layers in the corresponding regions, determining what those actions should be, and then implementing those actions. Additionally, in some embodiments, the process may operate in different orders and may be associated with a looping flow until a layout being processed has been balanced.

Abstract: The present disclosure provides an allogeneic whole cell cancer vaccine platform that includes compositions and methods for treating and preventing cancer. Provided herein are compositions containing a therapeutically effective amount of cells from one or more cancer cell lines, some or all of which are modified to (i) inhibit or reduce expression of one or more immunosuppressive factors by the cells, and/or (ii) express or increase expression of one or more immunostimulatory factors by the cells, and/or (iii) express or increase expression of one or more tumor-associated antigens (TAAs), including TAAs that have been mutated, and which comprise cancer cell lines that natively express a heterogeneity of tumor associated antigens and/or neoantigens. Also provided herein are methods of making the vaccine compositions, methods of preparing, and methods of use thereof.

Abstract: This invention relates to a compliance monitor for monitoring patient usage of a medicament delivery device, where the medicament delivery device includes a store of medicament and a medicament dispensing means. The compliance monitor includes a housing adapted to enclose the medicament delivery device, and a dose counter, associated with the housing, for recording the delivery of a dose of medicament to the patient from the medicament delivery device. The arrangement and construction is such that the housing is loosely coupled to the medicament delivery device, whereby the housing is able to move relative to the medicament delivery device during the delivery of the dose of medicament, and it is this movement which actuates the dose counter, either directly or indirectly, in order to record the delivery of the dose of medicament.

Abstract: A sprinkler includes a compartment that surrounds its riser portion in an offset or asymmetrical configuration. More specifically, the distance of the compartments walls from those of the riser vary (i.e., increase or decrease) at different locations surrounding the riser. Put another way, the riser is closer to one side of the compartment than other sides of the compartment. This non-concentric configuration allows larger components to fit inside the compartment than would otherwise fit if the riser was symmetrically surrounded by the compartment.

Abstract: The invention relates to a method of conducting a perf wash cement (“P/W/C”) abandonment job in an offshore oil or gas well annulus, in particular the washing or cementing operation using a rotating head with nozzles dispensing wash fluid or cement at pressure. A new design of bottom hole assembly is proposed in which the cementing tool has a relatively large diameter in order to optimize pressure whilst the wash tool has a relatively small diameter. The wash process, for a number of reasons, appears to be less sensitive to tool diameter and making the wash tool smaller reduces the overall risk of stuck pipe.

Abstract: Computer systems and methods generate data examples by training, through machine learning, a data generator with a training objective to produce a data example for a specific value of R, where R is value related to S1(x) and S2(x), where, for a data example, x, generated by the data generator, S1(x) is a likelihood that the data example x is in a first class of a first selected data example and S2(x) is a likelihood that the data example x is in a second class of a second selected data example. S1(x) and S2(x) are determined by a discriminator that is trained through machine learning to discriminate between the first and second classes. After training the data generator, the data generator generates a synthetic data example for each of multiple specific values of R.

Abstract: Various forms of anti-clog suction tips apparatus are disclosed. An exemplary anti-clog suction tip apparatus includes a suction tip assembly having a suction tip with a suction opening at a first end thereof for removing debris through suction, a hose attachment portion for attaching the suction tip assembly to a suction source, and an ejection wire channel. The apparatus further includes an ejection wire assembly having an ejection wire extending within the channel and an ejection button integral with or connected to the ejection wire. Applying a force to the ejection button advances the ejection wire through the channel such that an end portion of the ejection wire enters the suction tip and dislodges debris clogging the suction tip. The ejection wire may include an enlarged end portion such as, for example a ball tip. One or more of the components of the apparatus may be single-use and disposable.

Abstract: An adhesive article that remains securely bonded to a substrate until a stimuli is applied. The article may be embodied as an adhesive tape, a bandage, or as other articles. The stimuli may be a change in temperature or application of a reduction that causes a structure within the article to break, creak, or otherwise disrupt to expose the adhesive to a solvent, such as via a difference in Coefficient of Thermal Expansion (CTE) or by exposing the article to a glass transition temperature.

Abstract: Systems, devices, media, and methods are presented for an immersive augmented reality (AR) experience using an eyewear device with spatial audio. The eyewear device has a processor, a memory, an image sensor, and speakers. The eyewear device captures image information for an environment surrounding the device, identifies a match between objects in the image information and predetermined objects in previously obtained information for the same environment. The eyewear device then identifies a target location within the environment, which may be associated with a physical or a virtual object. The eyewear device monitors its orientation with respect to the target location and presents audio signals to guide the user toward the target location.

Abstract: A handguard assembly for installation on a firearm includes a handguard, an index block, a first fastener, and a second fastener. The handguard includes first and second clearance apertures and the index block includes first and second threaded apertures. The first and second fasteners extend through the respective first and second clearance apertures and threaded into the respective first and second threaded apertures. The first and second fasteners define respective first and second longitudinal axes that are non-parallel and non-collinear with each other. Tightening the first and second fasteners with respect to the index block secures the handguard to the index block and prevents movement of the handguard relative firearm.

Abstract: This document describes techniques and systems that enable a visual indicator for paused radar gestures. The techniques and systems use a radar field to enable an electronic device to accurately determine radar gestures, or other movement, by a user. Further, the electronic device can determine certain conditions that can make it difficult for the electronic device to properly determine the user's radar gestures. When the device includes an application that can be controlled using radar gestures (a radar-gesture application), and the conditions are present, the device can enter a gesture-paused mode. When the device enters this mode, the techniques provide a gesture-paused feedback element on a display, which lets the user know that there is at least one radar-gesture application available or running on the electronic device but that radar gestures cannot presently be used to control the application.

Abstract: A system for producing a flipbook includes a processor that receives a video comprising a plurality of frames, selects a start frame and an end frame, and a plurality of frames therebetween. The processor can analyze the frames of the segment to determine an average rate of change of the plurality of frames and a threshold of relative image difference based on the average rate of change of the plurality of frames and a baseline frame rate. The processor can select, based on the results of its analysis, a plurality of selected frames, each of the selected frames being separated from two other selected frames by a sub-segment of the video, wherein each pair of adjacent frames comprises a relative image difference above the threshold and wherein each selected frame meets quality criteria not met by one or more local frames.

Abstract: A high voltage power system is disclosed. In some embodiments, the high voltage power system includes a high voltage pulsing power supply; a transformer electrically coupled with the high voltage pulsing power supply; an output electrically coupled with the transformer and configured to output high voltage pulses with an amplitude greater than 1 kV and a frequency greater than 1 kHz; and a bias compensation circuit arranged in parallel with the output. In some embodiments, the bias compensation circuit can include a blocking diode; and a DC power supply arranged in series with the blocking diode.

Abstract: A condition monitoring device for monitoring machinery includes a combination of on-board sensors and a condition monitoring module. The on-board sensors include modules for non-contact temperature, magnetic flux and 3-axis vibration sensing of the machinery. The condition monitoring module provides a condition monitoring signal containing information about an operating condition of the machinery, based upon a data synthesis condition monitoring technique that synthesizes non-contact temperature, magnetic flux and 3-axis vibration sensed data received from the combination of on-board sensors, determines a current operating condition of the machinery, and compares the current operating condition and the baseline operating condition of the machinery.

Abstract: The present disclosure is directed to opposables including a body having a plurality of cavities disposed therein. Each cavity can be designed to contain one or more reagents, liquids, or fluids which may be applied to a specimen-bearing surface. In some embodiments, the cavities include one or more reagent chambers, the reagent chambers can have one or more seals such that the reagents, liquids, or fluids contained therein may be stored and released to the specimen-bearing surface.