Patents by Inventor James Audia

James Audia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lactam compound
    Publication number: 20070299053
    Abstract: The present invention provides crystalline (N)-((S)-2-hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one, a crystalline anydrate and dihydrates thereof, compositions comprising (N)-((S)-2-hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepin-2-one, its crystalline anhydrate or dihydrate, and methods for using the same.
    Type: Application
    Filed: January 11, 2006
    Publication date: December 27, 2007
    Inventors: James Audia, Benjamin Diseroad, Varghese John, Lee Latimer, Jeffrey Nissen, Gregory Stephenson, Eugene Thorsett, Jay Tung
  • Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20070203108
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: May 12, 2006
    Publication date: August 30, 2007
    Inventors: Eugene Thorsett, Michael Pleiss, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Bruce Dressman, James Droste, Steven Henry, Russell Stucky, Warren Porter
  • Methods and compounds for inhibiting beta-amyloid peptide release and/or its synthesis
    Publication number: 20060223761
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease Also disclosed pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: February 2, 2004
    Publication date: October 5, 2006
    Applicants: Elan Pharmaceuticals, Inc., Eli Lilly & Company
    Inventors: James Audia, Thomas Britton, James Droste, Beverly Folmer, George Huffman, Varghese John, Lee Latimer, Thomas Mabry, Jeffrey Nissen, Warren Porter, Jon Reel, Eugene Thorsett, Jay Tung, Jing Wu, Clark Eid, William Scott
  • Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20060079499
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: December 2, 2004
    Publication date: April 13, 2006
    Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, R. Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
  • Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20050272666
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: December 2, 2004
    Publication date: December 8, 2005
    Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, Jeffrey Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
  • Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20050267150
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: December 3, 2004
    Publication date: December 1, 2005
    Inventors: Richard Thompson, Stephen Wilkie, Douglas Stack, Eldon Vanmeter, Qing Shi, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, Steven Henry, Stacey McDaniel, Russell Stucky, Warren Porter
  • Lactam Compound
    Publication number: 20050261495
    Abstract: The present invention provides the compound (N)-((S)-2-hydroxy-3-methyl-butyryl)-1-(L-alaninyl)-(S)-1-amino-3-methyl-4,5,6,7-tetrahydro-2H-3-benzazepin-2-one, compositions thereof, and methods for using the same.
    Type: Application
    Filed: November 5, 2001
    Publication date: November 24, 2005
    Inventors: James Audia, Varghese John, Lee Latimer, Stacey McDaniel, Jeffrey Nissen, Eugene Thorsett, Jay Tung
  • CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
    Publication number: 20050215541
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: September 29, 2004
    Publication date: September 29, 2005
    Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, R. Jeffrey Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
  • Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20050203080
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: December 12, 2003
    Publication date: September 15, 2005
    Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, R. Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter
  • Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20050192269
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: December 3, 2004
    Publication date: September 1, 2005
    Inventors: Richard Thompson, Stephen Wilkie, Douglas Stack, Eldon Vanmeter, Qing Shi, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, Steven Henry, Stacey McDaniel, Russell Stucky, Warren Porter
  • Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20050192265
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions that include a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: December 3, 2004
    Publication date: September 1, 2005
    Inventors: Richard Thompson, Stephen Wilkie, Douglas Stack, Eldon Vanmeter, Qing Shi, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, Steven Henry, Stacey McDaniel, Russell Stucky, Warren Porter
  • Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting beta-amyloid peptide release and/or its synthesis by use of such compounds
    Publication number: 20050182046
    Abstract: Disclosed are compounds which inhibit ?-amyloid peptide release and/or its synthesis, and, accordingly, have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound which inhibits ?-amyloid peptide release and/or its synthesis as well as methods for treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
    Type: Application
    Filed: February 13, 2004
    Publication date: August 18, 2005
    Inventors: Jing Wu, Jay Tung, Eugene Thorsett, Michael Pleiss, Jeffrey Nissen, R. Neitz, Lee Latimer, Varghese John, Stephen Freedman, Thomas Britton, James Audia, Jon Reel, Thomas Mabry, Bruce Dressman, Cynthia Cwi, James Droste, Steven Henry, Stacey McDaniel, William Scott, Russell Stucky, Warren Porter