Patents by Inventor James B. Eckenhoff

James B. Eckenhoff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8298562
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: October 30, 2012
    Assignee: Intarcia Therapeutics, Inc.
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Bonnie J. Eckenhoff, legal representative, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Patent number: 8080259
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Grant
    Filed: December 29, 2009
    Date of Patent: December 20, 2011
    Assignee: Intarcia Therapeutics, Inc.
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Publication number: 20110230865
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Application
    Filed: May 26, 2011
    Publication date: September 22, 2011
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Bonnie J. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Publication number: 20100114074
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Application
    Filed: December 29, 2009
    Publication date: May 6, 2010
    Inventors: John R. Perry, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A, Magruder, Jeremy C. Wright
  • Patent number: 7655257
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Grant
    Filed: August 20, 2003
    Date of Patent: February 2, 2010
    Assignee: Intarcia Therapeutics, Inc.
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Bonnie J. Eckenhoff, legal representative, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Publication number: 20040039376
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Application
    Filed: August 20, 2003
    Publication date: February 26, 2004
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Patent number: 6682522
    Abstract: An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: January 27, 2004
    Assignee: Alza Corporation
    Inventors: John P. Carr, James B. Eckenhoff
  • Patent number: 6635268
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: October 21, 2003
    Assignee: Alza Corporation
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Publication number: 20030093063
    Abstract: An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.
    Type: Application
    Filed: December 4, 2002
    Publication date: May 15, 2003
    Inventors: John P. Carr, James B. Eckenhoff, Bonnie Burdett Dennis
  • Publication number: 20030031714
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Application
    Filed: March 28, 2002
    Publication date: February 13, 2003
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Patent number: 6508808
    Abstract: An osmotic delivery system for controlled delivery of a beneficial agent includes an implant capsule having a beneficial agent reservoir, an osmotic agent which expands on contact with fluid imbibed through a permeable membrane retained by the implant capsule, a delivery port, and a valve for opening and closing the delivery port. When the osmotic agent expands, a pressure is exerted against a separating member positioned between the beneficial agent reservoir and the osmotic agent. The separating member moves within the capsule, thereby forcing the valve to move a distance such that the beneficial agent can exit the reservoir through the delivery port.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: January 21, 2003
    Assignee: Alza Corporation
    Inventors: John P. Carr, James B. Eckenhoff
  • Patent number: 6395292
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: May 28, 2002
    Assignee: Alza Corporation
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Publication number: 20010031277
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Application
    Filed: May 4, 2001
    Publication date: October 18, 2001
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Patent number: 6283953
    Abstract: Performance of delivery systems for delivering beneficial agents to an animal are monitored to determine the delivery rate of the beneficial agent and the proper operation of the beneficial agent delivery device. Performance monitoring can be achieved by monitoring the physical configuration of the implanted osmotic delivery device from the exterior of the body to determine the amount of beneficial agent delivered and/or the delivery rate of the beneficial agent. The monitoring of the physical configuration of the implanted osmotic delivery device may be performed in different manners such as by X-ray or fluoroscopic monitoring of the implant structure or magnetic determination of a piston location within the implant. Performance monitoring can also be achieved by use of a performance marker within the beneficial agent to produce a specifically detectable response which can be measured noninvasively in body fluids or by-products.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: September 4, 2001
    Assignee: ALZA Corporation
    Inventors: Rupal Ayer, James B. Eckenhoff, Stephen A. Berry, Gregory R. Stewart, Scott D. Jordan
  • Patent number: 6261584
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: July 17, 2001
    Assignee: Alza Corporation
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright
  • Patent number: 6180129
    Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
    Type: Grant
    Filed: October 23, 1997
    Date of Patent: January 30, 2001
    Assignee: Alza Corporation
    Inventors: Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Peery
  • Patent number: 6156331
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: December 5, 2000
    Assignee: ALZA Corporation
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, deceased, Felix A. Landrau, Scott D. Lautenbach, Judy A Magruder, Jeremy C. Wright
  • Patent number: 6068850
    Abstract: This invention relates to stable liquid aqueous formulations of peptide compounds at high concentrations. These stable formulations comprise at least about 10% peptide in water. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery devices for long term delivery of drug.
    Type: Grant
    Filed: February 11, 1999
    Date of Patent: May 30, 2000
    Assignee: Alza Corporation
    Inventors: Cynthia L. Stevenson, Sally A. Tao, Steven J. Prestrelski, James B. Eckenhoff, deceased, Jeremy C. Wright, John J. Leonard, Jr.
  • Patent number: 6066619
    Abstract: This invention relates to stable non-aqueous protic formulations of peptide compounds. These stable formulations comprise peptide in non-aqueous protic solvent. They may be stored at elevated temperatures for long periods of time and are especially useful in implantable delivery devices for long term delivery of drug.
    Type: Grant
    Filed: April 16, 1999
    Date of Patent: May 23, 2000
    Assignee: Alza Corporation
    Inventors: Cynthia L. Stevenson, Sally A. Tao, Steven J. Prestrelski, James B. Eckenhoff, Jeremy C. Wright, John J. Leonard, Jr.
  • Patent number: 5985305
    Abstract: The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
    Type: Grant
    Filed: October 2, 1997
    Date of Patent: November 16, 1999
    Assignee: Alza Corporation
    Inventors: John R. Peery, Keith E. Dionne, James B. Eckenhoff, Felix A. Landrau, Scott D. Lautenbach, Judy A. Magruder, Jeremy C. Wright