Patents by Inventor James B. McClain

James B. McClain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11426494
    Abstract: A method for preparing a laminate coronary stent comprising: providing a stent framework; and depositing a plurality of layers on said stent framework to form said laminate coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: August 30, 2022
    Assignee: MT Acquisition Holdings LLC
    Inventors: James B. McClain, Charles Douglas Taylor, Robert Rabiner
  • Patent number: 11369498
    Abstract: Stent delivery systems having improved deliverability comprising an elongate member having an inflation lumen and a guidewire lumen therein; a balloon having an interior that is in fluid communication with the inflation lumen; and a stent comprising a coating mounted on the balloon. Methods for making stent delivery systems having improved deliverability. Methods for delivering two stent delivery systems concurrently through a guiding catheter, each stent delivery system comprising elongate member having an inflation lumen and a guidewire lumen therein, a balloon having an interior that is in fluid communication with the inflation lumen, and a stent comprising a coating mounted on the balloon. Stent coatings may comprise a pharmaceutical agent at least a portion of which is in crystalline form.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: June 28, 2022
    Assignee: MT Acquisition Holdings LLC
    Inventors: James B. McClain, Douglas Taylor, David Enscore
  • Publication number: 20210244861
    Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
    Type: Application
    Filed: April 29, 2021
    Publication date: August 12, 2021
    Applicant: MT Acquisition Holdings LLC
    Inventors: James P. DeYoung, Charles Douglas Taylor, James B. McClain, Clint Smoke, Mike Cole
  • Patent number: 11039943
    Abstract: A bioabsorbable biomedical implant is disclosed. The implant includes a tubular scaffold comprising a plurality of interconnected polymer struts. The interconnected polymer struts defines a plurality of deformable cells. The polymer struts have an average thickness of no more than 120 ?m. Methods for making the bioabsorbable biomedical implant, including the methods for making the polymer materials for the tubular scaffold, are also disclosed.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: June 22, 2021
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Charles Douglas Taylor
  • Publication number: 20210161687
    Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
    Type: Application
    Filed: January 25, 2021
    Publication date: June 3, 2021
    Applicant: Micell Technologies, Inc.
    Inventors: Charles Douglas Taylor, James B. McClain, Mike Cole, James P. DeYoung, Clint Smoke
  • Patent number: 11007307
    Abstract: A method for depositing a coating comprising a polymer and at least two pharmaceutical agents on a substrate, comprising the following steps: providing a stent framework; depositing on said stent framework a first layer comprising a first pharmaceutical agent; depositing a second layer comprising a second pharmaceutical agent; Wherein said first and second pharmaceutical agents are selected from two different classes of pharmaceutical agents.
    Type: Grant
    Filed: December 18, 2018
    Date of Patent: May 18, 2021
    Assignee: Micell Technologies, Inc.
    Inventors: James P. DeYoung, Charles Douglas Taylor, James B. McClain, Clint Smoke, Mike Cole
  • Publication number: 20210052781
    Abstract: Transfer rings for use in coating substrates and methods of utilizing same are disclosed. The transfer rings disclosed herein are useful in efficiently moving a plurality of substrates between different process chambers. For instance, the transfer rings are designed to collectively move a plurality of stents between coating and sintering chambers.
    Type: Application
    Filed: January 16, 2019
    Publication date: February 25, 2021
    Applicant: Micell Technologies, Inc.
    Inventors: David W. Gaddy, Meagan M. Fagan, James B. McClain
  • Patent number: 10898353
    Abstract: A method for depositing a coating comprising a polymer and pharmaceutical agent on a substrate, comprising the following steps: discharging at least one pharmaceutical agent in a therapeutically desirable morphology in dry powder form through a first orifice; discharging at least one polymer in dry powder form through a second orifice; depositing the polymer and/or pharmaceutical particles onto said substrate, wherein an electrical potential is maintained between the substrate and the pharmaceutical and/or polymer particles, thereby forming said coating; and sintering said coating under conditions that do not substantially modify the morphology of said pharmaceutical agent.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: January 26, 2021
    Assignee: Micell Technologies, Inc.
    Inventors: Charles Douglas Taylor, James B. McClain, Mike Cole, James P. DeYoung, Clint Smoke
  • Patent number: 10835396
    Abstract: A coated coronary stent, comprising a stainless steel sent framework coated with a primer layer of Parylene C, and a rapamycin-polymer coating having substantially uniform thickness disposed on the stent framework, wherein the rapamycin-polymer coating comprises polybutyl methacrylate (PBMA), polyethylene-co-vinyl acetate (PEVA) and rapamycin, wherein substantially all of the rapamycin in the coating is in amorphous form and substantially uniformly dispersed within the rapamycin-polymer coating.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: November 17, 2020
    Assignee: Micell Technologies, Inc.
    Inventors: Charles Douglas Taylor, James DeYoung, James B. McClain
  • Patent number: 10729819
    Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until implantable device is deployed a an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: August 4, 2020
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Charles Douglas Taylor, Brett G. Zani, John Neet, Timothy Charles Kiorpes
  • Publication number: 20200197578
    Abstract: A method for preparing a laminate coronary stent comprising: providing a stent framework; and depositing a plurality of layers on said stent framework to form said laminate coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer.
    Type: Application
    Filed: February 7, 2020
    Publication date: June 25, 2020
    Applicant: Micell Technologies, Inc.
    Inventors: James B. McClain, Charles Douglas Taylor, Robert Rabiner
  • Patent number: 10653820
    Abstract: Provided herein is a coated coronary stent, comprising: a. stent; b. a plurality of layers deposited on said stent to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: May 19, 2020
    Assignee: Micell Technologies, Inc.
    Inventors: Charles Douglas Taylor, James B. McClain
  • Patent number: 10617795
    Abstract: A method for preparing a laminate coronary stent comprising: providing a stent framework; and depositing a plurality of layers on said stent framework to form said laminate coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: April 14, 2020
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Charles Douglas Taylor, Robert Rabiner
  • Publication number: 20200108232
    Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.
    Type: Application
    Filed: December 5, 2019
    Publication date: April 9, 2020
    Applicant: Micell Technologies, Inc.
    Inventors: James B. McClain, Charles Douglas Taylor, Brett G. Zani, John Neet, Timothy Charles Kiorpes
  • Patent number: 10464100
    Abstract: A system and method are disclosed for coating surfaces of expandable medical devices with composite coatings. Coatings are composed of various materials including, e.g., polymers and drugs. Transfer of the coatings within a patient or other host forms a drug-eluting coating that delivers time-released drugs over time for treatment of a medical condition.
    Type: Grant
    Filed: May 30, 2012
    Date of Patent: November 5, 2019
    Assignees: Micell Technologies, Inc., Battelle Memorial Institute
    Inventors: Dean W. Matson, Clement R. Yonker, John L. Fulton, George S. Deverman, Barbara J. Tarasevich, Wendy J. Shaw, Leonard S. Fifield, Krys Wallace, C. Douglas Taylor, James B. McClain
  • Patent number: 10350391
    Abstract: Provided is a coated implantable medical device, comprising: a substrate; and a coating disposed on the substrate, wherein the coating comprises at least one polymer and at least one pharmaceutical agent in a therapeutically desirable morphology and/or at least one active biological agent and optionally, one or more pharmaceutical carrying agents; wherein substantially all of pharmaceutical agent and/or active biological agent remains within the coating and on the substrate until the implantable device is deployed at an intervention site inside the body of a subject and wherein upon deployment of the medical device in the body of the subject a portion of the pharmaceutical agent and/or active biological agent is delivered at the intervention site along with at least a portion of the polymer and/or a at least a portion of the pharmaceutical carrying agents.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: July 16, 2019
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Charles Douglas Taylor, John Neet, Brett G. Zani
  • Patent number: 10350333
    Abstract: Provided herein is a device comprising: a. stent; b. a plurality of layers on said stent framework to form said device; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: July 16, 2019
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Douglas Taylor
  • Publication number: 20190209742
    Abstract: Provided herein is a coated coronary stent, comprising: a. stent framework; b. a plurality of layers deposited on said stent framework to form said coronary stent; wherein at least one of said layers comprises a bioabsorbable polymer and at least one of said layers comprises one or more active agents; wherein at least part of the active agent is in crystalline form.
    Type: Application
    Filed: December 12, 2018
    Publication date: July 11, 2019
    Applicant: Micell Technologies, Inc.
    Inventors: James B. McClain, Charles Douglas Taylor
  • Publication number: 20190151453
    Abstract: A method of forming a drug/polymer composite material is carried out by combining a drug material with a polymer material under pressure in the presence of a compressed gas solvent (e.g., carbon dioxide) to form the drug/polymer composite material. Drug/polymer composite materials and shaped articles (e.g., subcutaneous drug depots) which may be produced by a process are also described, along with methods of use thereof.
    Type: Application
    Filed: January 28, 2019
    Publication date: May 23, 2019
    Applicant: Micell Technologies, Inc.
    Inventors: James B. McClain, James P. DeYoung
  • Patent number: 10293050
    Abstract: Provided is a drug delivery composition comprising at least one polymer and at least one active agent; wherein the active agent is present in crystalline form on at least one region of an outer surface of the composition and wherein active agent surface content is adjusted to provide a selected active agent release profile.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: May 21, 2019
    Assignee: Micell Technologies, Inc.
    Inventors: James B. McClain, Wenda C. Carlyle, Charles Douglas Taylor