Abstract: A computer-implemented method for targeted sweep of a key-value data storage is provided. The method comprises before a write transaction to a database having a key value store commits, and before each of one or more write commands of the write transaction are persisted to the key value store, writing an entry for each of the one or more write commands to an end of a targeted sweep queue, the entry comprising metadata including: data identifying a cell to which the write command relates, a start timestamp of the write transaction, and information identifying a type of the write transaction.

Abstract: The invention relates to bismuth-thiol compounds and pharmaceutical preparations thereof. The invention further relates to methods for treating a topical wound, comprising administering to a subject in need thereof a therapeutically effective amount of a composition comprising a bismuth-thiol compound, wherein the composition is applied to the infection. Methods for treating microbial infections such as diabetic foot infections are also provided.

Abstract: A solar electrical generator comprising an outer wall (1, 2) arranged to partially surround a cavity. A hub (3) is provided within the cavity wherein the outer face (4) of the wall is provided with solar cells (5). At least one of the hub (3) and the inner face (6) of the wall are provided with solar cells (5).

Abstract: A computer-implemented method for targeted sweep of a key-value data storage is provided. The method comprises before a write transaction to a database having a key value store commits, and before each of one or more write commands of the write transaction are persisted to the key value store, writing an entry for each of the one or more write commands to an end of a targeted sweep queue, the entry comprising metadata including: data identifying a cell to which the write command relates, a start timestamp of the write transaction, and information identifying a type of the write transaction.

Abstract: The invention relates to Bis-thiol compounds and pharmaceutical preparations thereof. The invention further relates to methods of treating, managing or lessening the severity of pulmonary infections in a subject, the method comprising administering to the subject a bismuth-thiol (BT) composition that comprises at least one BT compound.

Abstract: Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating acute wounds, chronic wounds and/or a wound or epithelial tissue surface that contains bacterial biofilm, including unexpected synergy between bismuth-thiol (BT) compounds and certain antibiotics, to provide topical formulations including antiseptic formulations, for management and promotion of wound healing and in particular infected wounds. Previously unpredicted antibacterial properties and anti-biofilm properties of disclosed BT compounds and BT compound-plus-antibiotic combinations are also described, including preferential efficacies of certain such compositions for treating gram-positive bacterial infections, and distinct preferential efficacies of certain such compositions for treating gram-negative bacterial infections.

Abstract: Example aspects include techniques for ordering operations in a file system having a hierarchical namespace including determining, by a first service that manages file system operations for a first entity in the hierarchical namespace, to perform a file system operation for the first entity, generating, by the first service, a first counter record for the file system operation, obtaining, based on determining to perform the file system operation and from a second service that manages file system operations on a second entity that is a parent of the entity in the hierarchical namespace, a second counter record for a last file system operation performed on the second entity, wherein the second counter record is generated by the second service, and storing, in a change feed, an indication of the file system operation along with the first counter record and the second counter record.

Abstract: Described herein are methods inducing the uptake of an agent by a cell. Aspects of the invention relate to physically compressing the cell to induce perturbations (e.g., holes) in the cell membrane or wall. An agent is taken up by the cell through induced perturbations.

Abstract: The invention relates to Bismuth thiol compounds such as BisEDT for treating bacterial and fungal infection in patients with viral pulmonary infections such as COVID-19, alone or in combination with other anti-viral drugs.

Abstract: Provided are methods and compositions for treating kidney disease, such as chronic kidney disease (CKD), in which the methods and compositions comprise antibodies or an antigen binding fragment thereof that specifically and selectively bind to human ?v?8 integrin, which was discovered, as described, to be highly expressed on kidney cells and tissue, and, in particular, diseased or fibrotic kidney tissue. The disclosed anti-?v?8 integrin antibodies bind to human ?v?8 integrin in the kidney and block the activation of TGF-? from its latent form in kidney tissue. The anti-?v?8 antibodies in the disclosed methods reduce, attenuate, or abrogate kidney fibrosis, which is associated with the activities of ?v?8 integrin and TGF-? in kidney tissue. The disclosed antibodies and methods effectively treat kidney disease, in particular, fibrosis associated with kidney disease, such as CKD, in individuals in need thereof.

Abstract: A distributed, transactional database uses timestamps, such as logical clock values, for entry versioning and transaction management in the database. To write to the database, a service requests a timestamp to be inserted into the database with a new version of data. During a backup procedure, a cleanup process is paused, issuing new timestamps is paused, and a backup timestamp is generated, which results in an effective backup copy. During a restore of a backup, a snapshot of the database is loaded and any entries older than the backup timestamp are deleted, which ensures that a consistent restore has occurred.

Abstract: Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating acute wounds, chronic wounds and/or a wound or epithelial tissue surface that contains bacterial biofilm, including unexpected synergy between bismuth-thiol (BT) compounds and certain antibiotics, to provide topical formulations including antiseptic formulations, for management and promotion of wound healing and in particular infected wounds. Previously unpredicted antibacterial properties and anti-biofilm properties of disclosed BT compounds and BT compound-plus-antibiotic combinations are also described, including preferential efficacies of certain such compositions for treating gram-positive bacterial infections, and distinct preferential efficacies of certain such compositions for treating gram-negative bacterial infections.

Abstract: Systems, methods, and non-transitory computer readable media are provided for recursively searching a plurality of workspaces of the system for linked data associated with the seed data, initiating an endpoint process for each the seed data and the linked data, and, upon completion of the search, delete the seed data and the linked data identified based at least in part on the endpoint process. The process may be automatically repeated at a predetermined time interval to identify and remove future data that is stored in the plurality of datasets.

Abstract: In a device including a processor and a computer-readable medium, the computer-readable medium includes executable instructions causing the processor to control the device to perform functions of (i) displaying, via a display, a GUI for a first communication application, the GUI including a first portion displaying content of a first communication session associated with the first communication application, wherein participants of the first communication session includes a user of the device, and a second portion including a plurality of graphical elements, each graphical element associated with one of a plurality of functionalities related to a second communication application different from the first communication application; (ii) detecting an activity related to a second communication session associated with the second communication application; and (iii) in response to detecting the activity, displaying, via the second portion of the GUI, an indication of the detected activity related to the second commu

Abstract: A system is provided for guiding a dielectric cable from a conductor to an elevated support structure. The system comprises: an insulator arranged to be attached to a conductor. The insulator comprises a first bore for receiving a dielectric cable. The system further comprises an earth bond extending to a lower end of the insulator; and a downpipe extending between first and second ends. The first end of the downpipe is connected to the lower end of the insulator and the second end of the downpipe is arranged to be supported by an elevated support structure. The downpipe is for receiving the dielectric cable from the bore of the insulator.

Abstract: Fiber optic cable assemblies having a construction suitable for a first deployment scenario where the optical connection is made to the device externally that may be transformed for a second deployment scenario where the optical connection is disposed within an internal cavity of the device are disclosed. The cable assembly has one or more cable legs disposed within a profile support element and are disposed under the heat shrink. The fiber optic connectors are exposed and suitable for optical connection with the heat shrink intact on the cable assembly and the profile support element further provides further flexibility using different outer housings with the cable assembly when making external optical connections to the device Thus, the concepts disclosed advantageously allow a single cable assembly to support multiple deployment scenarios in the field, thereby reducing complexity.

Abstract: present disclosure relates to a method of treating kidney injury, by administering an anti-IL-33 therapeutic agent which inhibits both ST2 signaling and RAGE signaling.

Abstract: A distributed, transactional database uses timestamps, such as logical clock values, for entry versioning and transaction management in the database. To write to the database, a service requests a timestamp to be inserted into the database with a new version of data. During a backup procedure, a cleanup process is paused, issuing new timestamps is paused, and a backup timestamp is generated, which results in an effective backup copy. During a restore of a backup, a snapshot of the database is loaded and any entries older than the backup timestamp are deleted, which ensures that a consistent restore has occurred.

Abstract: Systems, methods, and non-transitory computer readable media are provided for recursively searching a plurality of workspaces of the system for linked data associated with the seed data, initiating an endpoint process for each the seed data and the linked data, and, upon completion of the search, delete the seed data and the linked data identified based at least in part on the endpoint process. The process may be automatically repeated at a predetermined time interval to identify and remove future data that is stored in the plurality of datasets.

Abstract: The invention relates to Bis-thiol compounds and pharmaceutical preparations thereof. The invention further relates to methods of treating, managing or lessening the severity of pulmonary infections in a subject, the method comprising administering to the subject a bismuth-thiol (BT) composition that comprises at least one BT compound.