Patents by Inventor James Barrow

James Barrow has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250092686
    Abstract: The present disclosure relates to a building surface product that may include a substantially planar panel having a front surface, a rear surface, a first side, a second side, a first end, a second end, a gypsum body between the front surface and rear surface, and a first press-in fastener positioned on the rear surface of the substantially planar panel. The first press-in fastener may include a mending plate portion that may include a plurality of prongs inserted into the rear surface of the substantially planar panel, and a support structure attachment portion.
    Type: Application
    Filed: September 13, 2024
    Publication date: March 20, 2025
    Inventors: Colton MARSHALL, Kenneth Keefer, James LaLone, Sara A. Barrows, Natalia H. Thomas, Hooman Amid
  • Patent number: 12234221
    Abstract: Pyridine carboxamide compounds for inhibiting NaV1.8 and methods for treating a condition, disease, or disorder associated with an increased NaV1.8 activity or expression are disclosed.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: February 25, 2025
    Assignee: Lieber Institute, Inc.
    Inventors: Michael Poslusney, Glen Ernst, James Barrow, Yifang Huang
  • Publication number: 20250042855
    Abstract: Compounds and method for treating a disease, condition, or disorder associated with serotonin (5-HT) signaling, including gastroenterological disorders, such as colitis, irritable bowel syndrome (IBS), constipation, diarrhea, and gastroparesis, or extra-gastrointestinal disorders, such as asthma, migraine, itching, and osteoporosis. In some aspects, the compounds inhibit serotonin/5-HIT transporter (SERT).
    Type: Application
    Filed: December 1, 2022
    Publication date: February 6, 2025
    Inventors: Pankaj PASRICHA, James BARROW, Pablo DE LEON, Yifang HUANG, Qian LI
  • Publication number: 20240336574
    Abstract: The invention provides methyl-substituted pyridine and pyridazine compounds, derivatives thereof, and methods of their use. The compounds are useful as pharmacological agents to treat a variety of conditions, including various pain states, itch, and cough.
    Type: Application
    Filed: March 10, 2022
    Publication date: October 10, 2024
    Inventors: Robert M. Jones, Ashok Bajji, Nathaniel Julius Thomas Monck, Suzanne J. O'Connor, William H. Gardiner, Robert James Townsend, Andreina Pacheco Pita, Michael Brunavs, Abdul Kadar Shaikh, Jonathan Paul Shine, Ian James Wigginton, Jonathan Philip Richards, Marco Michele Mastandrea, Adam James Davenport, Bryan Moyer, Michael Poslusney, James Barrow, Richard Edmund Rathmell
  • Patent number: 11993581
    Abstract: Pyridazine compounds for inhibiting NaV1.8 and methods for treating a condition, disease, or disorder associated with an increased NaV1.8 activity or expression are disclosed.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: May 28, 2024
    Assignee: LIEBER INSTITUE, INC
    Inventors: Michael Poslusney, Glen Ernst, James Barrow
  • Publication number: 20230113490
    Abstract: A fixing mechanism for fixing a first panel to a second panel, having a first plate with a first longitudinal guide, the first guide comprising a first aperture at a first end of the first guide connected to a second aperture at a second end of the first guide via a longitudinal slot, the first aperture is greater than the second aperture; a second plate having a second guide complementary to the first guide, a retaining portion, an interlocking member configured to fasten the second plate to the first plate via the first and second guides and also to fasten the first and second plates to the first panel. The first plate and the second plate are fastened to the second panel via a second fastening means. The fixing mechanism advantageously provides a means for securely fixing two panels together, such as furniture panels, using minimal components.
    Type: Application
    Filed: October 13, 2022
    Publication date: April 13, 2023
    Applicant: Swyft Home Limited
    Inventors: James BARROW, John O'LEARY
  • Publication number: 20220356176
    Abstract: Compounds of formula (I), formula (II), or formula (III) and their use with a neurological or psychiatric disorder, mediated by Kv11.1-3.1 containing potassium channels, including schizophrenia, are disclosed.
    Type: Application
    Filed: June 11, 2020
    Publication date: November 10, 2022
    Inventors: Nicholas E. Calcaterra, Yifang Huang, Pablo DeLeon, James Barrow
  • Publication number: 20220227732
    Abstract: Pyridine carboxamide compounds for inhibiting NaV1.8 and methods for treating a condition, disease, or disorder associated with an increased NaV1.8 activity or expression are disclosed.
    Type: Application
    Filed: July 9, 2019
    Publication date: July 21, 2022
    Inventors: Michael Poslusney, Glen Ernst, James Barrow, Yifang Huang
  • Patent number: 11136322
    Abstract: The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance.
    Type: Grant
    Filed: March 4, 2019
    Date of Patent: October 5, 2021
    Assignees: The Johns Hopkins University, Lieber Institute, Inc.
    Inventors: Pankaj Pasricha, Yifang Huang, James Barrow
  • Publication number: 20210139479
    Abstract: This invention relates to compounds, pharmaceutical compositions and their use for treating neuropsychiatric and neurodegenerative disorders. In particular, the invention relates to inhibitors of catechol-O-methyltransferase and their use as therapeutics for central nervous system disease.
    Type: Application
    Filed: January 22, 2021
    Publication date: May 13, 2021
    Inventors: James Barrow, Glen Ernst, Dominique Swinnen, Florian Montel, Sabine Defays, Yifeng Huang, Pablo de Leon, Michael Steven Poslusney
  • Publication number: 20210139456
    Abstract: Pyridazine compounds for inhibiting NaV1.8 and methods for treating a condition, disease, or disorder associated with an increased NaV1.8 activity or expression are disclosed.
    Type: Application
    Filed: July 9, 2019
    Publication date: May 13, 2021
    Inventors: Michael Poslusney, Glen Ernst, James Barrow
  • Patent number: 10934283
    Abstract: Compounds that inhibit COMT enzyme and pharmaceutical compositions comprising the same are provided herein. Methods of treating various psychiatric and neurological disorders with the compounds and pharmaceutical compositions described herein are also provided.
    Type: Grant
    Filed: November 25, 2016
    Date of Patent: March 2, 2021
    Assignee: LIEBER INSTITUTE, INC.
    Inventors: James Barrow, Glen Ernst, Dominique Swinnen, Florian Montel, Sabine Defays, Yifang Huang, Pablo de León, Michael Steven Poslusney
  • Patent number: 10844070
    Abstract: The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance.
    Type: Grant
    Filed: February 13, 2020
    Date of Patent: November 24, 2020
    Assignees: The Johns Hopkins University, Lieber Institute, Inc.
    Inventors: Pankaj Pasricha, Yifang Huang, James Barrow
  • Patent number: 10748093
    Abstract: Embodiments of the present disclosure present a calculated value within a card view presentation in order to overcome technical problems in presenting useful card view presentations on mobile computing devices. In some embodiments, the calculated value is a summary, analysis, or other type of information generated based on data associated with cards that are in a given lane. In some embodiments, further technical problems relating to the limitations of the interface of the mobile computing device in adjusting calculated view settings are addressed by presenting a simplified configuration interface. The simplified configuration interface presents a mobile-friendly view of limited configuration settings to allow the user to easily change settings relevant to the calculated value and/or the card view, and thereby adjust the card view despite the limitations of the interface of the mobile computing device.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: August 18, 2020
    Assignee: Smartsheet Inc.
    Inventors: Christopher James Barrows, Jonathan Sandler
  • Patent number: 10705714
    Abstract: In some embodiments, a card view interface of tabular data is provided that is suitable for presentation on small displays such as those found on mobile computing devices. Cards from a single lane are displayed, along with a set of lane indicators. In some embodiments, when a drag operation is detected on a card, a size of the set of lane indicators is increased in order to facilitate dropping of the card on an intended lane indicator, thus helping to overcome the technical limitations of small mobile computing device displays.
    Type: Grant
    Filed: September 25, 2018
    Date of Patent: July 7, 2020
    Assignee: Smartsheet Inc.
    Inventors: Christopher James Barrows, Jonathan Sandler
  • Publication number: 20200181155
    Abstract: The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance.
    Type: Application
    Filed: February 13, 2020
    Publication date: June 11, 2020
    Inventors: Pankaj Pasricha, Yifang Huang, James Barrow
  • Publication number: 20200097871
    Abstract: Embodiments of the present disclosure present a calculated value within a card view presentation in order to overcome technical problems in presenting useful card view presentations on mobile computing devices. In some embodiments, the calculated value is a summary, analysis, or other type of information generated based on data associated with cards that are in a given lane. In some embodiments, further technical problems relating to the limitations of the interface of the mobile computing device in adjusting calculated view settings are addressed by presenting a simplified configuration interface. The simplified configuration interface presents a mobile-friendly view of limited configuration settings to allow the user to easily change settings relevant to the calculated value and/or the card view, and thereby adjust the card view despite the limitations of the interface of the mobile computing device.
    Type: Application
    Filed: September 25, 2018
    Publication date: March 26, 2020
    Applicant: Smartsheet Inc.
    Inventors: Christopher James Barrows, Jonathan Sandler
  • Publication number: 20200097151
    Abstract: In some embodiments, a card view interface of tabular data is provided that is suitable for presentation on small displays such as those found on mobile computing devices. Cards from a single lane are displayed, along with a set of lane indicators. In some embodiments, when a drag operation is detected on a card, a size of the set of lane indicators is increased in order to facilitate dropping of the card on an intended lane indicator, thus helping to overcome the technical limitations of small mobile computing device displays.
    Type: Application
    Filed: September 25, 2018
    Publication date: March 26, 2020
    Applicant: Smartsheet Inc.
    Inventors: Christopher James Barrows, Jonathan Sandler
  • Publication number: 20200062759
    Abstract: The present invention provides compounds and compositions which are positive allosteric modulators of GABA-A receptors that selectively target the peripheral nervous system and organs of the body, and which do not pass through the blood-brain barrier. The compounds and compositions of the present invention are useful for treatment of diseases or disorders which are mediated by GABA-A neuronal activity, such as, for example, visceral pain, gut motility, irritable bowel syndrome, functional abdominal pain, functional idiopathic diarrhea, inflammatory bowel diseases, drug induced pain, bile salt malabsorption, lactase or other carbohydrate intolerance.
    Type: Application
    Filed: March 4, 2019
    Publication date: February 27, 2020
    Inventors: Pankaj Pasricha, Yifang Huang, James Barrow
  • Patent number: 10479790
    Abstract: The present inventions include a method of inhibiting COMT enzyme in a subject as well as compounds of formula I, or a pharmaceutically acceptable salt thereof, that are useful in the treatment of various disorders mediated by COMT, including Parkinson's disease and/or schizophrenia.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: November 19, 2019
    Assignee: LIEBER INSTITUTE FOR BRAIN DEVELOPMENT
    Inventors: James Barrow, Glen Ernst, Yifang Huang, Ingrid Price Buchler, Daniel Weinberger