Abstract: Neural stimulation is effected by a stimulus current pulse. The current pulse is initially of an amplitude to rapidly induce a desired electrode voltage, and is subsequently of reduced amplitude to control electrode voltage in a desired manner. This can effect a reduced peak electrode voltage while delivering a given amount of charge. Optimization of the current pulse may further involve parameterising an electrode current waveform as a sequence of piecewise constant steps, each step having substantially the same duration as all other steps and each step having a calculatable amplitude, and identifying electrode-tissue interface (ETI) parameters. For each step of the pulse, the respective step amplitude is then calculated using the identified ETI parameters to optimise the electrode voltage.

Abstract: Neural stimulation is effected by a stimulus current pulse. The current pulse is initially of an amplitude to rapidly induce a desired electrode voltage, and is subsequently of reduced amplitude to control electrode voltage in a desired manner. This can effect a reduced peak electrode voltage while delivering a given amount of charge. Optimisation of the current pulse may further involve parameterising an electrode current waveform as a sequence of piecewise constant steps, each step having substantially the same duration as all other steps and each step having a calculatable amplitude, and identifying electrode-tissue interface (ETI) parameters. For each step of the pulse, the respective step amplitude is then calculated using the identified ETI parameters to optimise the electrode voltage.