Abstract: Described herein are compounds and methods for the treatment of coronavirus infection. The compounds can function as an inhibitor of the main protease (Mpro) of coronaviruses. The compounds can include diphenylmethyl piperazine derivatives, diphenylmethyl piperidine derivatives, diphenylmethylidene piperidine derivatives, tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen derivatives, tricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen derivatives, 6,11-dihydrobenzo[c][1]benzoxepin derivatives, 6,11-dihydrobenzo[c][1]benzothiepin derivatives, 5,5-dioxo-6,11-dihydrobenzo[c][1]benzothiepin derivatives, and 6-oxo-5,11-dihydrobenzo[c][1]benzazepin derivatives, as well as pharmaceutically acceptable salts, hydrates, and prodrugs thereof.

Abstract: Described herein are compounds, and methods for the treatment of coronavirus infection.

Abstract: A quick clamping device includes a main body adapted to be mounted on a mold holder, a clamp piece including first and second arm sections and pivoted to the main body between the first and second arm sections, a wedge body mounted movably on the main body below the second arm section, and a driving unit connected to the wedge body. The first arm section has a press end adapted to clamp a mold unit against the mold holder. The wedge body is movable between a first position, in which the wedge body lifts the second arm section so as to move downward the press end toward the mold unit, and a second position, in which the wedge body moves away from the first position.

Abstract: A quick clamping device includes a main body adapted to be mounted on a mold holder, a clamp piece including first and second arm sections and pivoted to the main body between the first and second arm sections, a wedge body mounted movably on the main body below the second arm section, and a driving unit connected to the wedge body. The first arm section has a press end adapted to clamp a mold unit against the mold holder. The wedge body is movable between a first position, in which the wedge body lifts the second arm section so as to move downward the press end toward the mold unit, and a second position, in which the wedge body moves away from the first position.