Abstract: Novel benzofurans, benzothiophenes and indoles useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.

Abstract: Novel quinazolinones useful as inhibitors of tau oligomer formation, useful for the treatment of neurodegenerative diseases and related conditions are disclosed. The invention also relates to the pharmaceutically acceptable salts of said compounds, processes for the preparation of said compounds, intermediates used in the preparation of said compounds, and pharmaceutical compositions containing said compounds. The invention further relates to methods of use of said compounds, salts of said compounds, and said compositions in treating neurodegenerative diseases and related conditions.

Abstract: A quick clamping device includes a main body adapted to be mounted on a mold holder, a clamp piece including first and second arm sections and pivoted to the main body between the first and second arm sections, a wedge body mounted movably on the main body below the second arm section, and a driving unit connected to the wedge body. The first arm section has a press end adapted to clamp a mold unit against the mold holder. The wedge body is movable between a first position, in which the wedge body lifts the second arm section so as to move downward the press end toward the mold unit, and a second position, in which the wedge body moves away from the first position.

Abstract: A quick clamping device includes a main body adapted to be mounted on a mold holder, a clamp piece including first and second arm sections and pivoted to the main body between the first and second arm sections, a wedge body mounted movably on the main body below the second arm section, and a driving unit connected to the wedge body. The first arm section has a press end adapted to clamp a mold unit against the mold holder. The wedge body is movable between a first position, in which the wedge body lifts the second arm section so as to move downward the press end toward the mold unit, and a second position, in which the wedge body moves away from the first position.