Abstract: The present discussion relates to structures and devices to facilitate application of an ultrasound therapy beam to a target anatomic region in a replicable manner. In certain aspects, adjustable positioning structures are described that allow a general probe positioning structure to be configured for a specific patient in a manner that allows the device to be used repeatedly to target the anatomic region, even when in non-clinical settings. In other aspects, a probe positioning structure is fabricated that is specific to a respective patient anatomy, such that use of the probe positioning structure provides repeatable targeting of the target anatomic region, even when in non-clinical settings.

Abstract: Embodiments of C4?-alkyl-ether heptamethine cyanine fluorophores according to general formula I, and pharmaceutically acceptable salts thereof, are disclosed. Methods of making and using the C4?-alkyl-ether heptamethine cyanine fluorophores also are disclosed.

Abstract: Embodiments of C4?-alkyl-ether heptamethine cyanine fluorophores according to general formula I, and pharmaceutically acceptable salts thereof, are disclosed. Methods of making and using the C4?-alkyl-ether heptamethine cyanine fluorophores also are disclosed.

Abstract: Embodiments of C4?-alkyl-ether heptamethine cyanine fluorophores according to general formula I, and pharmaceutically acceptable salts thereof, are disclosed. Methods of making and using the C4?-alkyl-ether heptamethine cyanine fluorophores also are disclosed.

Abstract: Embodiments of C4?-alkyl-ether heptamethine cyanine fluorophores according to general formula I, and pharmaceutically acceptable salts thereof, are disclosed. Methods of making and using the C4?-alkyl-ether heptamethine cyanine fluorophores also are disclosed.

Abstract: The apparatuses disclosed herein include a discharge lamp configured to emit ultraviolet and visible light, an optical filter configured to attenuate visible light, and a power circuit configured to operate the discharge lamp. Some embodiments of the apparatuses are configured such that ultraviolet light emitted from the discharge lamp and passed through the optical filter encircles an exterior surface of the apparatus. Some cases of the apparatuses include a sensor system configured to monitor a first parameter associated with the operation of the discharge lamp and a second parameter associated with the transmittance of the optical filter. Some of the apparatuses include a means for moving the optical filter while the apparatus is in operation. In some cases, the apparatuses may be configured such that the optical filter may be arranged in and out of alignment with the discharge lamp. In some embodiments, the optical filter may be a multifaceted.

Abstract: Apparatuses are disclosed which include a discharge lamp configured to emit ultraviolet light, a power circuit configured to operate the discharge lamp, and a reflector system configured to redirect ultraviolet light emitted from the discharge lamp. In some embodiments, the apparatuses include a support structure containing the power circuit and supporting the discharge lamp. In some of such embodiments, the reflector system is configured to redirect ultraviolet light propagating away from the support structure to a region exterior to the apparatus and which is between approximately 2 feet and approximately 4 feet from a floor of a room in which the apparatus is arranged. In other embodiments, the reflector system may be additionally or alternatively configured to redirect ultraviolet light propagating away from the support structure to encircle an exterior surface of the apparatus. In any case, the reflector system may, in some embodiments, include a repositionable reflector.

Abstract: The apparatuses disclosed herein include a discharge lamp configured to emit ultraviolet and visible light, an optical filter configured to attenuate visible light, and a power circuit configured to operate the discharge lamp. Some embodiments of the apparatuses are configured such that ultraviolet light emitted from the discharge lamp and passed through the optical filter encircles an exterior surface of the apparatus. Some cases of the apparatuses include a sensor system configured to monitor a first parameter associated with the operation of the discharge lamp and a second parameter associated with the transmittance of the optical filter. Some of the apparatuses include a means for moving the optical filter while the apparatus is in operation. In some cases, the apparatuses may be configured such that the optical filter may be arranged in and out of alignment with the discharge lamp. In some embodiments, the optical filter may be a multifaceted.

Abstract: Apparatuses are disclosed which include a discharge lamp configured to emit ultraviolet light, a power circuit configured to operate the discharge lamp, and a reflector system configured to redirect ultraviolet light emitted from the discharge lamp. In some embodiments, the apparatuses include a support structure containing the power circuit and supporting the discharge lamp. In some of such embodiments, the reflector system is configured to redirect ultraviolet light propagating away from the support structure to a region exterior to the apparatus and which is between approximately 2 feet and approximately 4 feet from a floor of a room in which the apparatus is arranged. In other embodiments, the reflector system may be additionally or alternatively configured to redirect ultraviolet light propagating away from the support structure to encircle an exterior surface of the apparatus. In any case, the reflector system may, in some embodiments, include a repositionable reflector.

Abstract: The apparatuses disclosed herein include a discharge lamp configured to emit ultraviolet and visible light, an optical filter configured to attenuate visible light, and a power circuit configured to operate the discharge lamp. Some embodiments of the apparatuses are configured such that ultraviolet light emitted from the discharge lamp and passed through the optical filter encircles an exterior surface of the apparatus. Some cases of the apparatuses include a sensor system configured to monitor a first parameter associated with the operation of the discharge lamp and a second parameter associated with the transmittance of the optical filter. Some of the apparatuses include a means for moving the optical filter while the apparatus is in operation. In some cases, the apparatuses may be configured such that the optical filter may be arranged in and out of alignment with the discharge lamp. In some embodiments, the optical filter may be a multifaceted.

Abstract: Apparatuses are disclosed which include a discharge lamp configured to emit ultraviolet light, a power circuit configured to operate the discharge lamp, and a reflector system configured to redirect ultraviolet light emitted from the discharge lamp. In some embodiments, the apparatuses include a support structure containing the power circuit and supporting the discharge lamp. In some of such embodiments, the reflector system is configured to redirect ultraviolet light propagating away from the support structure to a region exterior to the apparatus and which is between approximately 2 feet and approximately 4 feet from a floor of a room in which the apparatus is arranged. In other embodiments, the reflector system may be additionally or alternatively configured to redirect ultraviolet light propagating away from the support structure to encircle an exterior surface of the apparatus. In any case, the reflector system may, in some embodiments, include a repositionable reflector.

Abstract: A reaching apparatus is provided for allowing a user to utilize gross motor skills to actuate the reaching apparatus. The reaching apparatus includes a fixed and a sliding handle on a shaft. An internal pulley system is connected between the first and second handles such that sliding of the second handle activates the pulley system to move the claw of the reaching apparatus between an open and closed configuration. The claw may be locked in an open and/or closed configuration by rotation of the handle on the shaft. The pulley system can be set to specific resistance to activate the claw upon different gross motor levels.

Abstract: Devices are provided which include a component assembly for detecting inward, outward and sideways door movement. A component of the assembly extending from a structure comprises a distal end for contacting a door face when the structure is arranged in proximity to the door face. Systems are provided which include a portable stand, a door movement sensor attached to the stand, a proximity sensor, and a user interface. The system is configured to transmit signals to the user interface when the proximity sensor has been placed a predetermined distance from a door face and when door movement occurs. Apparatuses are provided which include program instructions for receiving input regarding a number of entryways of a room and inhibiting commencement of a task for which an apparatus arranged in the room is configured to perform until a number of signals received from a door movement sensor equals the number of entryways.

Abstract: Fluid applicators for use with topical medications are disclosed herein. An example apparatus includes a housing and a fluid container disposed inside the housing. The example apparatus also includes a pump assembly disposed inside the housing and fluidly coupled to the fluid container. The example apparatus further includes an applicator coupled to the housing. The applicator defines an outlet and has a surface to be in contact with an application site on a person. The surface is in fluid communication with the pump assembly via the outlet. The example apparatus also includes an actuator operatively coupled to the pump assembly. Movement of the actuator from a first position to a second position is to operate the pump to dispense a dose of the fluid onto the surface.

Abstract: A reaching apparatus is provided for allowing a user to utilize gross motor skills to actuate the reaching apparatus. The reaching apparatus includes a fixed and a sliding handle on a shaft. An internal pulley system is connected between the first and second handles such that sliding of the second handle activates the pulley system to move the claw of the reaching apparatus between an open and closed configuration. The claw may be locked in an open and/or closed configuration by rotation of the handle on the shaft. The pulley system can be set to specific resistance to activate the claw upon different gross motor levels.

Abstract: A reaching apparatus is provided for allowing a user to utilize gross motor skills to actuate the reaching apparatus. The reaching apparatus includes a fixed and a sliding handle on a shaft. An internal pulley system is connected between the first and second handles such that sliding of the second handle activates the pulley system to move the claw of the reaching apparatus between an open and closed configuration. The claw may be locked in an open and/or closed configuration by rotation of the handle on the shaft. The pulley system can be set to specific resistance to activate the claw upon different gross motor levels.

Abstract: Devices are provided which include a component assembly for detecting inward, outward and sideways door movement. A component of the assembly extending from a structure comprises a distal end for contacting a door face when the structure is arranged in proximity to the door face. Systems are provided which include a portable stand, a door movement sensor attached to the stand, a proximity sensor, and a user interface. The system is configured to transmit signals to the user interface when the proximity sensor has been placed a predetermined distance from a door face and when door movement occurs. Apparatuses are provided which include program instructions for receiving input regarding a number of entryways of a room and inhibiting commencement of a task for which an apparatus arranged in the room is configured to perform until a number of signals received from a door movement sensor equals the number of entryways.