Abstract: Heterofunctional segment-poly(ethylene glycol) polymers, conjugates of these molecules with therapeutic and/or imaging agents, and methods for their use are disclosed. The heterofunctional segment-poly(ethylene glycol) polymers are useful as drug delivery conjugates, i.e., the heterofunctional segment-poly(ethylene glycol) polymers can be covalently attached to therapeutic agents (e.g., pharmaceutically active agents) and serve as delivery vehicles for the therapeutic agents. The heterofunctional segment-poly(ethylene glycol) polymers are also useful as imaging agent conjugates, i.e. the heterofunctional segment-poly(ethylene glycol) polymers can be covalently attached to imaging agents (e.g., tracers, imaging atoms, and imaging molecules) and serve as delivery vehicles for the imaging agents. Also disclosed are methods for treating a subject by administering to the subject an effective amount of the polymers conjugated to a therapeutic agent, an imaging agent, or a mixture thereof.

Abstract: A well screen assembly includes an elongate base pipe, a shroud layer about the base pipe, and a mesh layer between the shroud layer and the base pipe. A portion of the mesh layer overlaps another position of the mesh layer to form an area of overlap. A spine is positioned proximate substantially an entire length of lie area of overlap, and transmits a force from the shroud layer to the mesh layer that compresses and seals the area of overlap against passage of particulate.

Abstract: A well screen assembly has an elongate base pipe having apertures therein. A filtration layer resides around the base pipe. A drainage assembly resides between the base pipe and the filtration layer. The drainage assembly includes a plurality of elongate risers carried on a mesh. The drainage layer supports the filtration layer apart from the elongate base pipe and defines an elongate passage between the base pipe and the filtration layer that communicates fluid laterally through the drainage assembly.

Abstract: The invention relates to a method for the production of high-strength ribbons having a high modulus of elasticity made of a highly molecular polyolefin, wherein the polyolefins, particularly polypropylene and polyethylene, are extruded through a slotted nozzle, are then subjected to a temperature of 85° to 135° C. for a duration of at least one second, the films are then cut into individual ribbons, if necessary, and stretched at temperatures between 90° and 165° C. in one or more steps, are rolled up or further processed directly into textiles or technical flexible sheet materials. The ribbons can be laminated into multi-layer flexible sheet materials by using adhesives or adhesion promoters, the flexible sheet materials being particularly suitable as protection from ballistic projectiles. In this case particularly in the form of plate-shaped or flexible compound bodies.

Abstract: Provided are compositions and methods for determining whether a tumor in a subject is sensitive or resistant to a chemotherapeutic agent. Further provided are methods and compositions for identifying a chemotherapeutic agent to which a subject's tumor is resistant or sensitive. Methods and compositions for selecting a chemotherapeutic agent for treating a subject with a tumor are also provided.

Abstract: A polyolefin plaque is made by hot compaction of an assembly of fibres of the oriented polymer. It has been found to be beneficial to subject the fibres to a prior crosslinking process. Hot compaction is then less temperature-sensitive and produces plaques with excellent hot strength properties. Preferably the fibres have been subjected to prior stages of irradiation and annealing, both in a non-oxidising environment, for example acetylene.

Abstract: An apparatus, systems and corresponding methods for a network of outdoor modular signs. Each outdoor sign is composed of various modules which combined make the sign fully contained and operable. Modules include paper-like displays, a wireless port, solar panels, battery packs and a frame. A network of such modular signs is placed within an outdoor area. A wireless station is provided with satellite link for receiving data where said data is presented as scheduled on the electronic paper-like display modules. Solar panel and/or battery pack modules power the displays. The outdoor modular sign is suitable for deployment in parking lots and other outdoor areas where a network of signs can be deployed in close proximity to each other providing engaging advertisement and messages to consumers walking through the defined outdoor areas.

Abstract: Human anti-epidermal growth factor receptor (EGFR) single-chain antibodies (scFvs) were isolated from a human IgM phage display library using purified epidermal growth factor receptor as antigen. Two isolates with different amino acid sequences were identified by ELISA as epidermal growth factor receptor-specific. The scFvs bind to the full length epidermal growth factor receptor and the truncated and/or mutated epidermal growth factor receptor on human cells. These anti-EGFR-scFvs are useful as therapeutic and/or diagnostic agents.

Abstract: An animal harness and leash combination is provided having an animal harness for circumscribing the torso of an animal. A pivoting attachment element is affixed to the upper portion of the animal harness and supports an extension arm rotatably affixed to a pivoting attachment. A leash is then capable of being removably attached to the vertically extended pivoting attachment to allow the leash to remain above the animal, thereby eliminating the possibility that the leash will become entangled with the animal's legs.

Abstract: A process for production of an article from a woven fabric of melt spun and drawn fibers or tapes of oriented polypropylene homopolymer or copolymer is disclosed, comprising subjecting the woven fabric of melt spun and drawn fibers or tapes to elevated temperature and pressure sufficient to melt a proportion of the polymer, characterised in that the draw ratio of said melt spun and drawn fibers or tapes is at least 7:1.

Abstract: A polyolefin plaque is made by hot compaction of an assembly of fibres of the oriented polymer. It has been found to be beneficial to subject the fibres to a prior crosslinking process. Hot compaction is then less temperature-sensitive and produces plaques with excellent hot strength properties. Preferably the fibres have been subjected to prior stages of irradiation and annealing, both in a non-oxidising environment, for example acetylene.

Abstract: A polyolefin plaque is made by hot compaction of an assembly of fibers of the oriented polymer. It has been found to be beneficial to subject the fibers to a prior crosslinking process. Hot compaction is then less temperature-sensitive and produces plaques with excellent hot strength properties. Preferably the fibers have been subjected to prior stages of irradiation and annealing, both in a non-oxidising environment, for example acetylene.

Abstract: A polyolefin plaque is made by hot compaction of an assembly of fibers of the oriented polymer. It has been found to be beneficial to subject the fibers to a prior crosslinking process. Hot compaction is then less temperature-sensitive and produces plaques with excellent hot strength properties. Preferably the fibers have been subjected to prior stages of irradiation and annealing, both in a non-oxidising environment, for example acetylene.

Abstract: A polyolefin plaque is produced by hot compaction of an assembly of melt spun oriented fibers. It has been found that good compaction can be achieved at relatively low compaction pressures, less than 10 MPa. Compaction can be carried out in an autoclave, rather than in a hot compaction press, and the mechanical properties of plaques so produced range from good to excellent.

Abstract: A polyolefin plaque is made by hot compaction of an assembly of fibers of the oriented polymer. It has been found to be beneficial to subject the fibers to a prior crosslinking process. Hot compaction is then less temperature-sensitive and produces plaques with excellent hot strength properties. Preferably the fibers have been subjected to prior stages of irradiation and annealing, both in a non-oxidizing environment, for example acetylene.

Abstract: A polyolefin plaque is produced by hot compaction of an assembly of melt spun oriented fibres. It has been found that good compaction can be achieved at relatively low compaction pressures, less than 10 Pa. Compaction can be carried out in an autoclave, rather than in a hot compaction press, and the mechanical properties of plaques so produced range from good to excellent.

Abstract: A power cut-off device comprises first and second electronic switching devices (FETs T2 and T1) which are cross-coupled so that when one switching device is on the other is off and vice versa, and a load (11) to be protected is connectable in series with the first switching device (FET T2). If the current through the first switching device (FET T2) exceeds a certain value, caused for example by a short circuit at the load, the second switching device (FET T1) is turned on to turn the first switching device off.

Abstract: A traffic control device has a base (14) and a sign (16) rotatably carried by the base. The sign has at least two sides, one of which bears a "GO" indication and the other a "STOP" indication. A radio control means (11) causes a motor in the base to position the sign with the "GO" and "STOP" sides alternately in substantially the same angular position relative to the base.