Abstract: Antibacterial compounds of formula (I) are provided: as well as stereoisomers and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

Abstract: Described herein are compositions and methods for intravenous administration of acetaminophen at a single dose level of less than about 1000 mg for the treatment or prevention of pain (e.g., postoperative pain) and/or fever.

Abstract: Methods, devices, and systems for facilitation of electronic message management involve receiving a message generated from a user of one communication system, augmenting the message with data indicative of the user, communicating the augmented message to a second communication system, and presenting the message to a user of the second communication system such that the message is separate from other received messages not having data indicative of the first user.

Abstract: An apparatus for monitoring performance comprises two elements: a first element (4) for attaching to a human or animal, containing two or more of physiological, biochemical, kinematic, and/or environmental sensors and a processing means which records in memory signals or derivates of signals from said sensors and contains a means of re-transmitting this data to a second element, and a second element (13, 16) containing a display (12, 17) or audio output to present the processed live or previous recorded data to the user.

Abstract: Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R8 and R9 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: Antibacterial compounds of formula (I) are provided: as well as stereoisomers and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

Abstract: A system and method for transaction bitcoin is described. Bitcoin can be sent to an email address. No miner's fee is paid by a host computer system. Hot wallet functionality is provided that transfers values of some Bitcoin addresses to a vault for purposes of security. A private key of a Bitcoin address of the vault is split and distributed to keep the vault secure. Instant exchange allows for merchants and customers to lock in a local currency price. A vault has multiple email addresses to authorize a transfer of bitcoin out of the vault. User can opt to have private keys stored in locations that are under their control. A tip button rewards content creators for their efforts. A bitcoin exchange allows for users to set prices that they are willing to sell or buy bitcoin and execute such trades.

Abstract: An arm positioning cushion for locating and supporting an arm of a patient above a base surface and in an orientation suitable for vascular radial access procedures. The arm positioning cushion includes a forearm support having a fingers contact surface at a first height above the base surface, an upwardly-curved wrist contact surface having an centerline apex at a second height above the base surface, and a first coupling portion. The arm positioning cushion also includes an elbow support having an elbow contact surface at a third height of the base surface, and a second coupling portion configured for linear-adjustable engagement with the first coupling portion to adjustably couple the forearm support to the elbow support. The third height is greater than the first height and less than the second height. In one aspect, the forearm support and elbow support may comprise a substantially homogeneous cushion material throughout.

Abstract: An automotive seat back foam pad assembly includes a seat back foam pad and a panel. The seat back foam pad is configured to receive a seat back frame and includes a side pocket. The side pocket has a sidewall portion and is configured to receive an air bag module. The panel is attached to the sidewall portion and attachable with the seat back frame. The panel is configured to maintain integrity of the sidewall portion during air bag module deployment.

Abstract: The present invention relates to the use of AxI as a biomarker for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) in a subject. More specifically, the invention relates to various methods for detecting the occurrence of epithelial-to-mesenchymal transition (EMT) in a subject by measuring AxI expression and/or activity.

Abstract: Antibacterial compounds of formula (I) are provided: as well as stereoisomers and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.

Abstract: Substrates may be bonded according to a method comprising contacting a first bonding surface of a first substrate with a second bonding surface of a second substrate to form an assembly; and compressing the assembly in the presence of an oxidizing atmosphere under suitable conditions to form a bonding layer between the first and second surfaces, wherein the first bonding surface comprises a polarized surface layer; the second bonding surface comprises a hydrophilic surface layer; the first and second bonding surfaces are different.

Abstract: Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R8 and R9 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: An apparatus for monitoring performance comprises two elements: a first element (4) for attaching to a human or animal, containing two or more of physiological, biochemical, kinematic, and/or environmental sensors and a processing means which records in memory signals or derivates of signals from said sensors and contains a means of re-transmitting this data to a second element, and a second element (13, 16) containing a display (12, 17) or audio output to present the processed live or previous recorded data to the user.

Abstract: Embodiments of a water treatment unit are disclosed. An embodiment of a water treatment unit according to the present disclosure comprises a generally vertical riser having a lower end and an upper end, at least one inlet adjacent the lower end, and at least one outlet adjacent the upper end, a substantially spherical housing surrounding the riser, the housing comprising at least one opening in a lower portion of the housing, the housing enclosing a chamber, a motor coupled to the housing, a shaft coupled to the motor, the shaft extending downward from the motor within the riser, the shaft being in general axial alignment with the riser, at least one propeller coupled to the shaft, and a biomedia material within the chamber.

Abstract: A fluid transport system and related methods is disclosed. The fluid transport system includes an elongated conduit having at least one fluid-transporting pathway. At least one heat tracing structure is bonded to a surface of the elongated conduit. A thermal conductor is removably positioned within the at least one heat tracing structure, wherein a quantity of thermal energy is transferred from the thermal conductor to the at least one fluid-transporting pathway. A bundle jacket is positioned about the exterior of the elongated conduit and the at least one heat tracing structure.

Abstract: Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein Q1, Q2, Q3, R8 and R9 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.

Abstract: An apparatus for monitoring performance comprises two elements: a first element (4) for attaching to a human or animal, containing two or more of physiological, biochemical, kinematic, and/or environmental sensors and a processing means which records in memory signals or derivates of signals from said sensors and contains a means of re-transmitting this data to a second element, and a second element (13, 16) containing a display (12, 17) or audio output to present the processed live or previous recorded data to the user.

Abstract: An arm positioning cushion for locating and supporting an arm of a patient above a base surface and in an orientation suitable for vascular radial access procedures. The arm positioning cushion includes a forearm support having a fingers contact surface at a first height above the base surface, an upwardly-curved wrist contact surface having an centerline apex at a second height above the base surface, and a first coupling portion. The arm positioning cushion also includes an elbow support having an elbow contact surface at a third height of the base surface, and a second coupling portion configured for linear-adjustable engagement with the first coupling portion to adjustably couple the forearm support to the elbow support. The third height is greater than the first height and less than the second height. In one aspect, the forearm support and elbow support may comprise a substantially homogeneous cushion material throughout.