Abstract: The present application provides compositions and methods for treating a patient with cancer, and in particular epithelial tumors and carcinomas, with antibodies directed to CD33-like Siglecs.

Abstract: A system and method for aligning an inertial reference system, which is coupled to a moveable body, is provided. The method includes obtaining unaided navigation state information from an unaided source, and obtaining aiding state information from an aiding source. The unaided navigation state information is generated by the unaided source using navigation information provided by an inertial reference, and the aiding state information is generated by the aiding source using navigation information provided by at least one external reference. The method also includes determining an unaided navigation solution using the unaided navigation state information, and determining an aided navigation solution using a combination of the unaided and aiding state information. As a default, the method provides the unaided navigation solution for navigating the movable body.

Abstract: A system and method for aligning an inertial reference system, which is coupled to a moveable body, is provided. The method includes obtaining unaided navigation state information from an unaided source, and obtaining aiding state information from an aiding source. The unaided navigation state information is generated by the unaided source using navigation information provided by an inertial reference, and the aiding state information is generated by the aiding source using navigation information provided by at least one external reference. The method also includes determining an unaided navigation solution using the unaided navigation state information, and determining an aided navigation solution using a combination of the unaided and aiding state information. As a default, the method provides the unaided navigation solution for navigating the movable body.

Abstract: A novel buying guide means detachably secured to a newspaper or magazine insert is provided. The multi-page buying guide includes check list with indicators to note and organize an inventory of shopping items and coupons from the accompanying newspaper or insert. Redeemable coupons for use in conjunction with the buying guide are provided in the accompanying insert. The buying guide further includes pouch means within the guide for coupons representing products indicated on the guide. Indicators are printed adjacent selected products to notify the buyer that coupons related to particular items on the checklist are located in the accompanying insert.