Abstract: Described are systems, techniques, and processes for pathology detection in radiological images. A process can include obtaining a radiological image corresponding to an imaged anatomical area. Based on processing the radiological image using a semantic segmentation neural network, a target map can be generated corresponding to a plurality of candidate anatomical defect locations within the cropped radiological image. At least one volume of interest (VOI) can be generated centered around a particular candidate anatomical defect location within the cropped radiological image. A classification neural network can be used to classify the particular candidate anatomical defect location within the cropped radiological image, wherein classifying the particular candidate anatomical defect location includes determining a pathology associated with the particular candidate anatomical defect location.

Abstract: Described are techniques for uncertainty-aware anatomical landmark detection, using, for example, a deep reinforcement learning (DRL) anatomical landmark detection agent. For instance, a process can include generating one or more image features for an input medical image using a first sub-network of the anatomical landmark detection agent. A softmax layer of a second sub-network of the anatomical landmark detection agent can generate a plurality of discrete Q-value distributions for a set of allowable actions associated with movement of the agent within the medical image. An anatomical landmark location within the medical image can be predicted using the discrete Q-value distributions. An uncertainty can be determined for the predicted anatomical landmark location, based on an average full width half maximum (FWHM) calculated for the plurality of discrete Q-value distributions.

Abstract: Various deficiencies in the prior art are addressed by systems, methods, architectures, mechanisms and/or apparatus configured to fuse data received from a plurality of sensor sources on a network. The fusing data includes forming an empirical distribution for each of the sensor sources, reformatting the data from each of the sensor sources into pre-rotational alpha-trimmed depth regions, applying an affine transformation rotation to each of the reformatted data to form post-rotational pre-rotational alpha-trimmed depth regions, and reformatting each affine transformation into a new data fusion operator.

Abstract: Various deficiencies in the prior art are addressed by systems, methods, architectures, mechanisms and/or apparatus configured to fuse data received from a plurality of sensor sources on a network. The fusing data includes forming an empirical distribution for each of the sensor sources, reformatting the data from each of the sensor sources into pre-rotational alpha-trimmed depth regions, applying an affine transformation rotation to each of the reformatted data to form post-rotational pre-rotational alpha-trimmed depth regions, and reformatting each affine transformation into a new data fusion operator.

Abstract: A surgical implant is provided for implantation into a body of a patient to treat a vaginal prolapse in the patient. The surgical implant is made of non-absorbable material and includes a knitted mesh having a mass density of less than 25 g/m2. The knitted mesh includes polypropylene strands having a diameter of less than about 600 ?m, major spaces located between adjacent ones of the strands, the major spaces having a width of from about 1 mm to 10 mm, and pores located within the strands, the pores having a diameter of from about 50 ?m to 200 ?m. The knitted mesh is secured in place to treat the prolapse.

Abstract: A method for providing support to a urethra in treating urinary incontinence includes passing first and second elongate members coupled to a urethral support through an incision in the vaginal wall, around sides of the urethra and behind a pubic bone. The method includes locating the urethral support under the urethra applying tension to one of the elongate members with a rotary force tensioner and adjusting tension of the urethral support.

Abstract: Various embodiments of vehicle occupant safety systems having extendable restraints for use with, for example, airbags are described herein. In one embodiment, for example, the disclosed technology includes a 2-point occupant restraint that secures an occupant in an aircraft seat. In this embodiment, the aircraft seat is positioned in a seating area that includes a forward monument housing a stowed airbag. In the event of a crash or other significant dynamic event that causes, for example, a rapid deceleration of the aircraft above a preset magnitude, the airbag deploys between the occupant and the monument as the dynamic forces cause the occupant to pitch forward. The forward momentum of the occupant's body creates a significant tension load in the 2-point restraint, which causes the restraint to extend by a preset amount, thereby allowing the occupant to move forward in the seat more than the occupant would have moved had the occupant been wearing a conventional, non-extending 2-point restraint.

Abstract: Various embodiments of vehicle occupant safety systems having extendable restraints for use with, for example, airbags are described herein. In one embodiment, for example, the disclosed technology includes a 2-point occupant restraint that secures an occupant in an aircraft seat. In this embodiment, the aircraft seat is positioned in a seating area that includes a forward monument housing a stowed airbag. In the event of a crash or other significant dynamic event that causes, for example, a rapid deceleration of the aircraft above a preset magnitude, the airbag deploys between the occupant and the monument as the dynamic forces cause the occupant to pitch forward. The forward momentum of the occupant's body creates a significant tension load in the 2-point restraint, which causes the restraint to extend by a preset amount, thereby allowing the occupant to move forward in the seat more than the occupant would have moved had the occupant been wearing a conventional, non-extending 2-point restraint.

Abstract: A surgical device that is implantable to treat female urinary incontinence includes a support, a first suspending member connected to the support, a second suspending member connected to the support, a first anchor connected to the first suspending member, and a second anchor connected to the second suspending member. Microgrooves are formed in a surface of at least one of the first suspending member and the second suspending member.

Abstract: A method of treating urinary incontinence is disclosed. The method includes guiding a tip of an introducer tool through a length of a soft tissue anchor and out of an end of the soft tissue anchor. The method includes pushing the tip of the introducer tool and the soft tissue anchor into tissue on a side of a urethra, penetrating the tissue with the tip of the introducer tool, and delivering the soft tissue anchor into the tissue. The method includes removing the tip of the introducer tool from the soft tissue anchor and allowing a plurality of projections connected to the soft tissue anchor to expand thus anchoring the soft tissue anchor in the tissue.

Abstract: An implant configured to treat prolapse of a pelvic organ includes a support member and an extension portion projecting from the support member. The extension portion has a barbed fixation means provided thereon for anchoring the extension portion into pelvic paravaginal tissue. The barbed fixation means allow bi-directional adjustment of the barbed fixation means relative to the tissue, and when suitably located, the barbed fixation means engage the tissue. The support member comprises a mesh material having a mass density of less than 50 g/m2.

Abstract: A surgical device that is implantable to treat female urinary incontinence includes a support, a first suspending member connected to the support, a second suspending member connected to the support, a first anchor connected to the first suspending member, and a second anchor connected to the second suspending member. Microgrooves are formed in a surface of at least one of the first suspending member and the second suspending member.

Abstract: Various embodiments of vehicle occupant safety systems having extendable restraints for use with, for example, airbags are described herein. In one embodiment, for example, the disclosed technology includes a 2-point occupant restraint that secures an occupant in an aircraft seat. In this embodiment, the aircraft seat is positioned in a seating area that includes a forward monument housing a stowed airbag. In the event of a crash or other significant dynamic event that causes, for example, a rapid deceleration of the aircraft above a preset magnitude, the airbag deploys between the occupant and the monument as the dynamic forces cause the occupant to pitch forward. The forward momentum of the occupant's body creates a significant tension load in the 2-point restraint, which causes the restraint to extend by a preset amount, thereby allowing the occupant to move forward in the seat more than the occupant would have moved had the occupant been wearing a conventional, non-extending 2-point restraint.

Abstract: A surgical implant is provided for implantation into a body of a patient to treat a vaginal prolapse in the patient. The surgical implant is made of non-absorbable material and includes a knitted mesh having a mass density of less than 25 g/m2. The knitted mesh includes polypropylene strands having a diameter of less than about 600 ?m, major spaces located between adjacent ones of the strands, the major spaces having a width of from about 1 mm to 10 mm, and pores located within the strands, the pores having a diameter of from about 50 ?m to 200 ?m. The knitted mesh is secured in place to treat the prolapse.

Abstract: A method for providing support to a urethra in treating urinary incontinence includes passing first and second elongate members coupled to a urethral support through an incision in the vaginal wall, around sides of the urethra and behind a pubic bone. The method includes locating the urethral support under the urethra applying tension to one of the elongate members with a rotary force tensioner and adjusting tension of the urethral support.

Abstract: A surgical device that is implantable to treat female urinary incontinence includes a support, a first suspending member connected to the support, a second suspending member connected to the support, a first anchor connected to the first suspending member, and a second anchor connected to the second suspending member. A distance measured along the second suspending member between the second anchor and the support is adjustable.

Abstract: A method of treating pelvic organ prolapse in a female patient by accessing a prolapsed organ trans-vaginally through a vagina is disclosed. The method includes making an incision through a wall of a vagina of the female patient, and providing an implant with a mesh having a mass density of 50 g/m2 or less. The method additionally includes radially confining the implant with a tool, and inserting a portion of the tool and the implant through the incision formed in the wall of the vagina. The method includes releasing the implant from the tool in an area of the prolapsed organ in supporting the vagina of the female patient.

Abstract: A method of post-operatively adjusting a urethral support in treating urinary incontinence of a woman is disclosed. The method includes passing a support through an incision and locating the support under a urethra. The support is a porous mesh adapted to allow tissue in-growth. The method include adjusting the support by applying tension to one of a first member that is secured to a first end of the support or a second member that is secured to a second end of the support. The first member and the second member each has an end that exits the skin. The first and second members are adapted to prevent tissue in-growth into the first member and the second member.

Abstract: Master flange assemblies are disclosed herein. In one embodiment, a master flange assembly includes a master flange and a tube. The master flange includes a central aperture, at least one through-hole, and a plurality of cavities. The tube is arranged to pass through the central aperture and form the master flange assembly when secured to the master flange. In one embodiment, the plurality of cavities are recessions formed in a first surface of the master flange, wherein the recessions do not pass through the master flange. In one embodiment, the plurality of cavities are separated by ribs. In one embodiment, the master flange includes a shoulder recessed from a second surface of the master flange and adjacent to the central aperture. The tube includes a rim that engages the shoulder of the master flange when the tube is secured to the master flange to form the assembly.

Abstract: Various embodiments of vehicle occupant safety systems having extendable restraints for use with, for example, airbags are described herein. In one embodiment, for example, the disclosed technology includes a 2-point occupant restraint that secures an occupant in an aircraft seat. In this embodiment, the aircraft seat is positioned in a seating area that includes a forward monument housing a stowed airbag. In the event of a crash or other significant dynamic event that causes, for example, a rapid deceleration of the aircraft above a preset magnitude, the airbag deploys between the occupant and the monument as the dynamic forces cause the occupant to pitch forward. The forward momentum of the occupant's body creates a significant tension load in the 2-point restraint, which causes the restraint to extend by a preset amount, thereby allowing the occupant to move forward in the seat more than the occupant would have moved had the occupant been wearing a conventional, non-extending 2-point restraint.