Patents by Inventor James Bruce Yarnton Haycock Behrendorff

James Bruce Yarnton Haycock Behrendorff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Arginine supplementation to improve efficiency in gas fermenting acetogens
    Patent number: 11965201
    Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.
    Type: Grant
    Filed: March 16, 2021
    Date of Patent: April 23, 2024
    Assignee: LanzaTech NZ, Inc.
    Inventors: Kaspar Valgepea, Michael Koepke, James Bruce Yarnton Haycock Behrendorff, Esteban Marcellin, Lars K. Nielsen, Renato de S. P. Lemgruber
  • PRODUCTION OF POLYHYDROXYBUTYRATE IN WOOD-LJUNGDAHL MICROORGANISMS
    Publication number: 20220213517
    Abstract: The invention provides microorganisms and methods for the production of polyhydroxybutyrate (PHB) from gaseous substrates. In particular, the invention provides a non-naturally occurring Wood-Ljungdahl microorganism comprising (a) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (b) an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and (c) an enzyme that converts 3-hydroxybutyryl-CoA to polyhydroxybutyrate, and methods related thereto.
    Type: Application
    Filed: March 25, 2022
    Publication date: July 7, 2022
    Inventors: Ryan Christopher Tappel, James Bruce Yarnton Haycock Behrendorff, Michael Koepke, Esteban Marcellin, Renato de Souza Pinto Lemgruber, Kaspar Valgepea, Lars Nielsen
  • Wood-Ljungdahl microorganisms that produce polyhydroxybutyrate
    Patent number: 11306333
    Abstract: The invention provides microorganisms and methods for the production of polyhydroxybutyrate (PHB) from gaseous substrates. In particular, the invention provides a non-naturally occurring Wood-Ljungdahl microorganism comprising (a) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (b) an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and (c) an enzyme that converts 3-hydroxybutyryl-CoA to polyhydroxybutyrate, and methods related thereto.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: April 19, 2022
    Assignee: LanzaTech, Inc.
    Inventors: Ryan Christopher Tappel, James Bruce Yarnton Haycock Behrendorff, Michael Koepke, Esteban Marcellin, Renato de Souza Pinto Lemgruber, Kaspar Valgepea, Lars Nielsen
  • ARGININE SUPPLEMENTATION TO IMPROVE EFFICIENCY IN GAS FERMENTING ACETOGENS
    Publication number: 20210230648
    Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.
    Type: Application
    Filed: March 16, 2021
    Publication date: July 29, 2021
    Inventors: Kaspar Valgepea, Michael Koepke, James Bruce Yarnton Haycock Behrendorff, Esteban Marcellin, Lars K. Nielsen, Renato de S.P. Lemgruber
  • Arginine supplementation to improve efficiency in gas fermenting acetogens
    Patent number: 10995347
    Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: May 4, 2021
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, James Bruce Yarnton Haycock Behrendorff, Kaspar Valgepea, Esteban Marcellin, Lars K. Nielsen, Renato de S.P. Lemgruber
  • PRODUCTION OF POLYHYDROXYBUTYRATE IN WOOD-LJUNGDAHL MICROORGANISMS
    Publication number: 20190119706
    Abstract: The invention provides microorganisms and methods for the production of polyhydroxybutyrate (PHB) from gaseous substrates. In particular, the invention provides a non-naturally occurring Wood-Ljungdahl microorganism comprising (a) an enzyme that converts acetyl-CoA to acetoacetyl-CoA, (b) an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and (c) an enzyme that converts 3-hydroxybutyryl-CoA to polyhydroxybutyrate, and methods related thereto.
    Type: Application
    Filed: October 4, 2018
    Publication date: April 25, 2019
    Inventors: Ryan Christopher Tappel, James Bruce Yarnton Haycock Behrendorff, Michael Koepke, Esteban Marcellin, Renato de Souza Pinto Lemgruber, Kaspar Valgepea, Lars Nielsen
  • Genetically engineered microorganisms for the production of chorismate-derived products
    Patent number: 10174303
    Abstract: The invention provides genetically engineered microorganisms and methods for producing chorismate-derived products, such as para-hydroxybenzoic acid, salicylate, 2-aminobenzoate, 2,3-dihydroxybenzoate, and 4-hydroxycyclohexane carboxylic acid. Typically, the microorganism comprises at least one of (a) an exogenous chorismate pyruvate lyase, (b) an exogenous isochorismate synthase, (c) an exogenous isochorismate pyruvate lyase, and (d) a prephenate synthase comprising a disruptive mutation.
    Type: Grant
    Filed: May 26, 2016
    Date of Patent: January 8, 2019
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: James Bruce Yarnton Haycock Behrendorff, Michael Koepke, Loan Phuong Tran, Wyatt Eric Allen
  • Genetically engineered bacterium for the production of 3-hydroxybutyrate
    Patent number: 9957531
    Abstract: The invention relates to a genetically engineered bacterium having an enzyme that converts acetyl-CoA to acetoacetyl-CoA, an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and an enzyme that converts 3-hydroxybutyryl-CoA to 3-hydroxybutyrate. The bacterium may also have enzymes to produce other downstream products, such as 3-hydroxybutyryaldehyde, and 1,3-butanediol. Typically, the bacterium is capable of producing these products from a gaseous substrate, such as syngas or an industrial waste gas.
    Type: Grant
    Filed: July 25, 2017
    Date of Patent: May 1, 2018
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, Rasmus Overgaard Jensen, James Bruce Yarnton Haycock Behrendorff, Ryan Edward Hill, Darmawi Juminaga, Alexander Paul Mueller
  • GENETICALLY ENGINEERED BACTERIUM FOR THE PRODUCTION OF 3-HYDROXYBUTYRATE
    Publication number: 20180105847
    Abstract: The invention relates to a genetically engineered bacterium having an enzyme that converts acetyl-CoA to acetoacetyl-CoA, an enzyme that converts acetoacetyl-CoA to 3-hydroxybutyryl-CoA, and an enzyme that converts 3-hydroxybutyryl-CoA to 3-hydroxybutyrate. The bacterium may also have enzymes to produce other downstream products, such as 3-hydroxybutyryaldehyde, and 1,3-butanediol. Typically, the bacterium is capable of producing these products from a gaseous substrate, such as syngas or an industrial waste gas.
    Type: Application
    Filed: July 25, 2017
    Publication date: April 19, 2018
    Inventors: Michael Koepke, Rasmus Overgaard Jensen, James Bruce Yarnton Haycock Behrendorff, Ryan Edward Hill, Darmawi Juminaga, Alexander Paul Mueller
  • Genetically engineered bacterium comprising energy-generating fermentation pathway
    Patent number: 9738875
    Abstract: The invention relates to a genetically engineered bacterium comprising an energy-generating fermentation pathway and methods related thereto. In particular, the invention provides a bacterium comprising a phosphate butyryltransferase (Ptb) and a butyrate kinase (Buk) (Ptb-Buk) that act on non-native substrates to produce a wide variety of products and intermediates. In certain embodiments, the invention relates to the introduction of Ptb-Buk into a C1-fixing microoorgansim capable of producing products from a gaseous substrate.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: August 22, 2017
    Assignee: LANZATECH NEW ZEALAND LIMITED
    Inventors: Michael Koepke, Rasmus Overgaard Jensen, James Bruce Yarnton Haycock Behrendorff, Ryan Edward Hill
  • ARGININE SUPPLEMENTATION TO IMPROVE EFFICIENCY IN GAS FERMENTING ACETOGENS
    Publication number: 20170159083
    Abstract: The invention provides methods for improving efficiency of fermentation by arginine supplementation, and genetically modified bacterium for use therefor. More particularly the invention provides methods for (i) increasing the production ATP intensive products with arginine supplementation, (ii) increasing utilization of arginine by a C1-fixing bacterium; and (iii) providing C1-fixing bacterium with optimized arginine de-aminase pathways.
    Type: Application
    Filed: December 2, 2016
    Publication date: June 8, 2017
    Inventors: Kaspar Valgepea, Michael Koepke, James Bruce Yarnton Haycock Behrendorff, Esteban Marcellin, Lars K. Nielsen, Renato de S.P. Lemgruber
  • GENETICALLY ENGINEERED BACTERIUM COMPRISING ENERGY-GENERATING FERMENTATION PATHWAY
    Publication number: 20170101631
    Abstract: The invention relates to a genetically engineered bacterium comprising an energy-generating fermentation pathway and methods related thereto. In particular, the invention provides a bacterium comprising a phosphate butyryltransferase (Ptb) and a butyrate kinase (Buk) (Ptb-Buk) that act on non-native substrates to produce a wide variety of products and intermediates. In certain embodiments, the invention relates to the introduction of Ptb-Buk into a C1-fixing microoorgansim capable of producing products from a gaseous substrate.
    Type: Application
    Filed: October 13, 2016
    Publication date: April 13, 2017
    Inventors: Michael Koepke, Rasmus Overgaard Jensen, James Bruce Yarnton Haycock Behrendorff, Ryan Edward Hill
  • GENETICALLY ENGINEERED MICROORGANISMS FOR THE PRODUCTION OF CHORISMATE-DERIVED PRODUCTS
    Publication number: 20160348087
    Abstract: The invention provides genetically engineered microorganisms and methods for producing chorismate-derived products, such as para-hydroxybenzoic acid, salicylate, 2-aminobenzoate, 2,3-dihydroxybenzoate, and 4-hydroxycyclohexane carboxylic acid. Typically, the microorganism comprises at least one of (a) an exogenous chorismate pyruvate lyase, (b) an exogenous isochorismate synthase, (c) an exogenous isochorismate pyruvate lyase, and (d) a prephenate synthase comprising a disruptive mutation.
    Type: Application
    Filed: May 26, 2016
    Publication date: December 1, 2016
    Inventors: James Bruce Yarnton Haycock Behrendorff, Michael Koepke, Loan Phuong Tran, Wyatt Eric Allen