Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt thereof, or an N-oxide thereof) of formula (I), which are positive allosteric modulators of one or more GABA-A receptors, e.g., which are peripherally restricted, positive allosteric modulators of one or more GABA-A receptors; e.g., which are positive allosteric modulators of one or more GABA-A receptors and which selectively target the peripheral nervous system and organs of the body, and which do not substantially pass through the blood-brain barrier. Said compounds are useful e.g., for the treatment of systemic diseases of the body, e.g., diseases in which modulation of one or more peripherally restricted GABA-A receptors is beneficial (e.g., diseases or disorders which are mediated by GABA-A neuronal activity. This disclosure also features pharmaceutical compositions containing the chemical entities described herein as well as methods of using same for the treatment of systemic diseases of the body.

Abstract: A system and method for cleaning steam generators is disclosed as comprising a housing disposed within the steam generator, a cartridge removably disposed within the housing, deliming crystals disposed within the cartridge, a water inlet port fluidically connected to the housing for permitting water to enter the housing and the cartridge so as to mix with the deliming crystals so as to form a deliming crystalline solution, a water exit port fluidically connected to the housing for permitting the deliming crystalline solution to flow out from the housing, and a control system operatively connected to the housing and to the source of water so as to control water fill and drain cycles throughout the steam generator so as to permit the deliming crystalline solution to flow through the steam generator, delime the valves, valve seats, and water fill probes, and be drained out from the steam generator upon completion of the cleaning operation.

Abstract: A flash steamer water control system for use in connection with the flash-steam cooking of food items comprises a heated platen, an electric power supply for supplying electrical power to the heated platen, a water discharge mechanism for discharging water onto the heated platen such that the water discharged onto the heated platen will be flashed into steam, and a control system operatively connected to the water discharge mechanism for controlling the water discharge mechanism so as to permit the water discharge mechanism to discharge water onto the heated platen only when the temperature level of the heated platen is at or above a predetermined temperature level so as to effectively guarantee that the water, discharged from the water discharge mechanism onto the heated platen, will be flashed into steam throughout a predeterminedly timed flash-steamed cooking cycle without overwhelming the heated platen and flooding the same.

Abstract: A capacitive sensing system for the detection and quantification of food products disposed within a food warming drawer or food storage container is disclosed and comprises an electrically grounded metal plate, and a printed circuit board (PCB) having a plurality of capacitive sensing pads disposed thereon and which effectively serve as capacitive sensors capable of detecting and measuring the capacitance of an object in proximity to it. The system, in conjunction with known detection circuitry, outputs or generates digital number signals which are indicative of the capacitance of the items or food products disposed within the food warming drawer or storage container. The system can therefore be utilized to detect the presence and number of food items disposed within the food warming drawer or container, as well as whether or not the food items are disposed within a vertically stacked array or disposed in a side-by-side array.