Patents by Inventor James C. Cook

James C. Cook has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8124108
    Abstract: The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full-length S. epidermidis polypeptide. The full-length naturally occurring polypeptide is referred to herein as full-length ORF1319e. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. epidermidis.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: February 28, 2012
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Annaliesa S. Anderson, Tessie McNeely, James C. Cook, III, William L. McClements, Donna L. Montgomery
  • Patent number: 7782002
    Abstract: A switch-type power converter comprising an PET switch operating in a variable duty cycle mode under the control of a Unitrode 3846 integrated circuit controller. Indications of excess input voltage and reverse battery connections are provided by circuits including an element which permanently changes state. A cooling fan mounted on a finned heat sink is operated in a variable speed mode. A single thermistor sensor provides inputs to both the fan speed control and a thermal shutdown circuit connected to shut down the gate drives to the FET switch in the event of a high temperature condition. Another shutdown function is provided in response to an input overvoltage condition by way of an operational amplifier. The converter uses foldback for short circuit protection and is compatible with microprocessor units to selectively provide multiple output voltage levels.
    Type: Grant
    Filed: September 8, 2005
    Date of Patent: August 24, 2010
    Assignee: Progressive Dynamics, Inc.
    Inventor: James C. Cook, II
  • Publication number: 20100143390
    Abstract: The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full-length S. epidermidis polypeptide. The full-length naturally occurring polypeptide is referred to herein as full-length ORF1319e. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. epidermidis.
    Type: Application
    Filed: January 18, 2008
    Publication date: June 10, 2010
    Inventors: Annaliesa S. Anderson, Tessie McNeely, James C. Cook, III, William L. McClements, Donna L. Montgomery
  • Publication number: 20100104591
    Abstract: The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 and uses of such polypeptides. SEQ ID NO: 1 is a truncated derivative of a full-length S. epidermidis polypeptide. The full-length naturally occurring polypeptide is referred to herein as full-length ORF2695e. A His-tagged derivative of SEQ ID NO: 1 was found to produce a protective immune response against S. epidermidis.
    Type: Application
    Filed: March 14, 2008
    Publication date: April 29, 2010
    Inventors: Annaliesa S. Anderson, Tessie McNeely, James C. Cook III, William L. McClements, Donna L. Montgomery
  • Patent number: 7552130
    Abstract: A computerized method, program product, and a service that facilitates the storage of multiple rows of data in a relational database. If the data is clustered data, the method, program product and the service first obtains the clustered data from its source. An identifying primary key of the clustered data is resolved, and the clustered data is parsed, compressed and stored as a binary large object (BLOB). The BLOB may be stored within the relational database or may be stored separately. Storage and access times for large amount of data used in relational databases are optimized.
    Type: Grant
    Filed: October 17, 2006
    Date of Patent: June 23, 2009
    Assignee: International Business Machines Corporation
    Inventors: James C. Cook, Patrick E. McCamish, Gary M. Quesenberry, Robert C. Robinson, Jr., John S. Warren
  • Publication number: 20080144341
    Abstract: A switch-type power converter includes a double FET switch operating in a variable duty cycle mode under the control of a Unitrode 3846 integrated circuit controller. Indications of excess input voltage and reverse battery connections are provided by circuits including an element which permanently changes state. A cooling fan mounted on a finned heat sink is operated in a variable speed mode.
    Type: Application
    Filed: January 14, 2008
    Publication date: June 19, 2008
    Applicant: Progressive Dynamics, Inc.
    Inventor: James C. Cook
  • Publication number: 20080091698
    Abstract: A computerized method, program product, and a service that facilitates the storage of multiple rows of data in a relational database. If the data is clustered data, the method, program product and the service first obtains the clustered data from its source. An identifying primary key of the clustered data is resolved, and the clustered data is parsed, compressed and stored as a binary large object (BLOB). The BLOB may be stored within the relational database or may be stored separately. Storage and access times for large amount of data used in relational databases are optimized.
    Type: Application
    Filed: October 17, 2006
    Publication date: April 17, 2008
    Applicant: International Business Machines Corporation
    Inventors: James C. Cook, Patrick E. McCamish, Gary M. Quesenberry, Robert C. Robinson, John S. Warren
  • Patent number: 7188156
    Abstract: Disclosed are embodiments of a method, a system and a computer program product for selecting data to be presented in a report form. A selector window is displayed to a user, the selector window displaying periods of time for indicating those periods of time for which data is available. The periods of time are displayed as a stack of temporally aligned time lines that are each partitioned into time periods of different duration, where each partition of a given time line has a spatial extent that differs from the spatial extent of partitions of other time lines, with longer partitions encompassing a plurality of shorter partitions. In response to the user selecting a point on a time line, the method, system and computer program product displays a report of that data.
    Type: Grant
    Filed: March 20, 2003
    Date of Patent: March 6, 2007
    Assignee: International Business Machines Corporation
    Inventors: Randal Lee Bertram, Dawn Ashley Comfort, Frederick Scott Hunter Krauss, James C. Cook
  • Patent number: 7157443
    Abstract: A high molecular weight polysaccharide intracellular adhesin (SAE) antigen having the general structure of poly-1,6,?-2-amidoglucopyranoside, which is variable substituted with N-acetyl and O-succinyl substituents is described. Also, a method is given for isolating this antigen from Staphylococcus aureus. The SAE can be used in a vaccine, either alone, conjugated to an immunogenic protein, and/or with an immunogenic adjuvant.
    Type: Grant
    Filed: December 6, 2002
    Date of Patent: January 2, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Joseph G. Joyce, James C. Cook, III, Chitrananda Abeygunawardana, Karen M. Grimm, Craig T. Przysiecki, Robert W. Hepler, Charlotte C. Ip, Keith Roper, Qiuwei Xu, Kathrin U. Jansen, Paul M. Keller, Leslie D. Cope
  • Patent number: 6991795
    Abstract: Human Papillomavirus virus like particles (VLPs) have been constructed so that they contain a modified L2 protein. The L2 protein has been minimized and is fused to a second protein or peptide. The fused protein is incorporated into the VLP and the VLP can deliver the protein to a cell. The modified VLPs can be used to increase the breadth of immune response in vaccine preparations or to deliver other proteins of interest.
    Type: Grant
    Filed: August 10, 1999
    Date of Patent: January 31, 2006
    Assignee: Merck & Co., Inc.
    Inventors: Robert S. Lowe, Kathrin U. Jansen, Joseph G. Joyce, William L. McClements, James C. Cook, III, Jessica Ching-Yee Ling, Michael P. Neeper
  • Publication number: 20040259838
    Abstract: A high molecular weight polysaccharide intracellular adhesin (SAE) antigen having the general structure of poly-1,6,&bgr;-2-amidoglucopyranoside, which is variable substituted with N-acetyl and O-succinyl substituents is described. Also, a method is given for isolating this antigen from Staphylococcus aureus. The SAE can be used in a vaccine, either alone, conjugated to an immunogenic protein, and/or with an immunogenic adjuvant.
    Type: Application
    Filed: June 9, 2004
    Publication date: December 23, 2004
    Inventors: Joseph G. Joyce, James C. Cook III, Chitrananda Abeygunawardana, Karen M. Grimm, Craig T. Przysiecki, Robert W. Hepler, Charlotte C. Ip, Donald Keith Roper, Qi Wei Xu, Kathrin U. Jansen, Paul M. Keller, Leslie D. Cope
  • Publication number: 20040199826
    Abstract: Disclosed are embodiments of a method, a system and a computer program product for selecting data to be presented in a report form. A selector window is displayed to a user, the selector window displaying periods of time for indicating those periods of time for which data is available. The periods of time are displayed as a stack of temporally aligned time lines that are each partitioned into time periods of different duration, where each partition of a given time line has a spatial extent that differs from the spatial extent of partitions of other time lines, with longer partitions encompassing a plurality of shorter partitions. In response to the user selecting a point on a time line, the method, system and computer program product displays a report of that data.
    Type: Application
    Filed: March 20, 2003
    Publication date: October 7, 2004
    Applicant: International Business Machines Corporation
    Inventors: Randal Lee Bertram, Dawn Ashley Comfort, Frederick Scott Hunter Krauss, James C. Cook
  • Publication number: 20040080542
    Abstract: A method, system, and computer program product for displaying, administrating and modifying client-sided cascading choices containing data levels and data items. The invention includes the operations of associating variables for each data level and each data item and generating visibility rules that define the visibility of each data level and each data item at the client display, wherein the visibility rules include at least some of the associated variables.
    Type: Application
    Filed: October 28, 2002
    Publication date: April 29, 2004
    Applicant: International Business Machines Corporation
    Inventors: Randal L. Bertram, James C. Cook, Patrick E. McCamish, Gary M. Quesenberry
  • Patent number: 6602697
    Abstract: A process for purifying papillomavirus virus-like particles (VLPs) includes the step of passing a partially purified VLP-containing solution through a hydroxyapatite chromatography column. The VLPs are then eluted using a buffer containing phosphate anion. The advantages of this method include the recovery of a high yield of intact VLPs.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: August 5, 2003
    Assignee: Merck & Co., Inc.
    Inventor: James C. Cook, III
  • Patent number: 5888516
    Abstract: Recombinant expression vectors encoding the L1 and L2 proteins of papillomavirus, methods of making and using the recombinant proteins and purified virus-like particles comprised of the recombinant proteins are provided.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: March 30, 1999
    Assignee: Merck & Co. Inc.
    Inventors: Kathrin U. Jansen, James C. Cook, III, Hugh A. George, Kathryn J. Hofmann, Joseph G. Joyce, Ernest Dale Lehman, Henry Z. Markus, Mark Rosolowsky, Loren S. Schultz
  • Patent number: 5687066
    Abstract: A switched power converter for a recreational vehicle includes a housing and a switched power supply. The switched power supply has a switch and at least one energy storage component, the switch controlling the supply of power to the energy storage component. The output of the energy storage component is a regulated DC output voltage. A controller generates a switching control signal for controlling the state of said switch. A protection circuit is connected to the controller for protecting the switched power supply from damage resulting when a reverse battery connection is made. The circuit also includes a controller for controlling the pulse-width of the control signals input to the switch. A fan may be provided on the housing which is selectively enabled to move cooling air over the switched power supply only when a detected temperature exceeds a threshold level. The controller may be disabled when an ambient temperature exceeds a threshold level.
    Type: Grant
    Filed: April 6, 1995
    Date of Patent: November 11, 1997
    Assignee: Progressive Dynamics, Inc.
    Inventor: James C. Cook, II
  • Patent number: 5600550
    Abstract: A switched power converter for a recreational vehicle includes a housing and a switched power supply. The switched power supply has a switch and at least one energy storage component, the switch controlling the supply of power to the energy storage component. The output of the energy storage component is a regulated DC output voltage. A controller generates a switching control signal for controlling the state of said switch. A protection circuit is connected to the controller for protecting the switched power supply from damage resulting when a reverse battery connection is made. The circuit also includes a controller for controlling the pulse-width of the control signals input to the switch. A fan may be provided on the housing which is selectively enabled to move cooling air over the switched power supply only when a detected temperature exceeds a threshold level. The controller may be disabled when an ambient temperature exceeds a threshold level.
    Type: Grant
    Filed: June 8, 1994
    Date of Patent: February 4, 1997
    Assignee: Progressive Dynamics, Inc.
    Inventor: James C. Cook, II
  • Patent number: 5272426
    Abstract: A light system is disclosed for controlling the amount of light supplied from a high density light source to a target. A shutter is positioned between the light source and the target, and a motor is coupled to said shutter to control the position of said shutter. Either manual or automatic control of said shutter is provided by electronic means coupled to said motor.
    Type: Grant
    Filed: March 18, 1991
    Date of Patent: December 21, 1993
    Assignee: James C. Cook
    Inventor: James C. Cook, II
  • Patent number: 5034663
    Abstract: A power supply for a gas discharge lamp includes a current regulator for regulating the current supplied to a lamp and current steering means for steering current from the current regulator in alternating directions through an isolation transformer primary winding, the secondary winding of the transformer being connected with a lamp through an arc striking circuit. The frequency of alternating the current through the transformer is controlled as a function of the lamp voltage in order to regulate the volt-second product of the transformer through all portions of a lamp operating cycle including arc striking. This reduces saturation of the transformer and allows a much smaller transformer to be used. In a preferred embodiment, the current regulation and steering functions are performed in a bridge circuit having FET switches in each leg and in which the transformer primary spans the sides of the bridge.
    Type: Grant
    Filed: April 21, 1989
    Date of Patent: July 23, 1991
    Assignee: Progressive Dynamics, Inc.
    Inventors: James C. Cook, II, Larry Eccleston
  • Patent number: D365082
    Type: Grant
    Filed: September 15, 1993
    Date of Patent: December 12, 1995
    Assignee: Progressive Dynamics, Inc.
    Inventors: James C. Cook, II, Jeffrey L. Cornell