Patents by Inventor James C. Copeland

James C. Copeland has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11771722
    Abstract: Methods of inhibiting or reducing tumor metabolism and growth are disclosed. A composition containing oxygen scavenging membrane fragments and anaerobe bacteria is injected into a tumor to interfere with tumor growth and metabolism, leading to tumor necrosis. The composition may also contain a cryoprotectant, which permits the composition to be stored at sub-zero temperatures without freezing.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: October 3, 2023
    Assignee: Oxyrase, Inc.
    Inventor: James C. Copeland
  • Patent number: 11286450
    Abstract: A culture system includes a dish and a lid. The dish comprises a base, a sidewall extending from the base, and a track extending outwardly from an outer surface of the sidewall. The lid comprises a central horizontal wall and a recess formed by two sidewalls and a top wall. At least one key extends downwardly from the recess. The sidewall of the dish extends into the recess of the lid, and the key engages the track. The track is shaped so that the lid rises or falls relative to the base of the dish when the lid is rotated relative to the dish.
    Type: Grant
    Filed: August 29, 2019
    Date of Patent: March 29, 2022
    Assignee: Oxyrase, Inc.
    Inventors: James C. Copeland, John E. Richey
  • Patent number: 11207386
    Abstract: Methods of inhibiting or reducing tumor metabolism and growth are disclosed. A composition containing oxygen scavenging membrane fragments is administered within a tumor to create a hypoxic environment. This interferes with tumor growth and metabolism, and can lead to tumor death.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: December 28, 2021
    Assignee: Oxyrase, Inc.
    Inventor: James C. Copeland
  • Publication number: 20200353017
    Abstract: Methods of inhibiting or reducing tumor metabolism and growth are disclosed. A composition containing oxygen scavenging membrane fragments and anaerobe bacteria is injected into a tumor to interfere with tumor growth and metabolism, leading to tumor necrosis. The composition may also contain a cryoprotectant, which permits the composition to be stored at sub-zero temperatures without freezing.
    Type: Application
    Filed: July 27, 2020
    Publication date: November 12, 2020
    Inventor: James C. Copeland
  • Patent number: 10722543
    Abstract: Methods of inhibiting or reducing tumor metabolism and growth are disclosed. A composition containing oxygen scavenging membrane fragments and anaerobe bacteria is injected into a tumor to interfere with tumor growth and metabolism, leading to tumor necrosis. The composition may also contain a cryoprotectant, which permits the composition to be stored at sub-zero temperatures without freezing.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: July 28, 2020
    Assignee: Oxyrase, Inc.
    Inventor: James C. Copeland
  • Patent number: 10611996
    Abstract: Methods of preserving and storing biological specimens, particularly anaerobe microorganisms are disclosed. A composition containing oxygen scavenging membrane fragments and a cryoprotectant is administered to the specimens. The specimens are then stored at a temperature that is lower than 0° C. and greater than ?70° C. Cryogenic freezing is not required.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: April 7, 2020
    Assignee: OXYRASE, INC.
    Inventor: James C. Copeland
  • Publication number: 20200080040
    Abstract: A culture system includes a dish and a lid. The dish comprises a base, a sidewall extending from the base, and a track extending outwardly from an outer surface of the sidewall. The lid comprises a central horizontal wall and a recess formed by two sidewalls and a top wall. At least one key extends downwardly from the recess. The sidewall of the dish extends into the recess of the lid, and the key engages the track. The track is shaped so that the lid rises or falls relative to the base of the dish when the lid is rotated relative to the dish.
    Type: Application
    Filed: August 29, 2019
    Publication date: March 12, 2020
    Inventors: James C. Copeland, John E. Richey
  • Publication number: 20190008928
    Abstract: Methods of inhibiting or reducing tumor metabolism and growth are disclosed. A composition containing oxygen scavenging membrane fragments is administered within a tumor to create a hypoxic environment. This interferes with tumor growth and metabolism, and can lead to tumor death.
    Type: Application
    Filed: September 12, 2018
    Publication date: January 10, 2019
    Inventor: James C. Copeland
  • Patent number: 10076556
    Abstract: Methods of inhibiting or reducing tumor metabolism and growth are disclosed. A composition containing oxygen scavenging membrane fragments is administered within a tumor to create a hypoxic environment. This interferes with tumor growth and metabolism, and can lead to tumor death.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: September 18, 2018
    Assignee: OXYRASE, INC.
    Inventor: James C. Copeland
  • Publication number: 20170216371
    Abstract: Methods of inhibiting or reducing tumor metabolism and growth are disclosed. A composition containing oxygen scavenging membrane fragments and anaerobe bacteria is injected into a tumor to interfere with tumor growth and metabolism, leading to tumor necrosis. The composition may also contain a cryoprotectant, which permits the composition to be stored at sub-zero temperatures without freezing.
    Type: Application
    Filed: January 26, 2017
    Publication date: August 3, 2017
    Inventor: James C. Copeland
  • Publication number: 20170218325
    Abstract: Methods of preserving and storing biological specimens, particularly anaerobe microorganisms are disclosed. A composition containing oxygen scavenging membrane fragments and a cryoprotectant is administered to the specimens. The specimens are then stored at a temperature that is lower than 0° C. and greater than ?70° C. Cryogenic freezing is not required.
    Type: Application
    Filed: January 26, 2017
    Publication date: August 3, 2017
    Inventor: James C. Copeland
  • Publication number: 20160220646
    Abstract: Methods of inhibiting or reducing tumor metabolism and growth are disclosed. A composition containing oxygen scavenging membrane fragments is administered within a tumor to create a hypoxic environment. This interferes with tumor growth and metabolism, and can lead to tumor death.
    Type: Application
    Filed: January 28, 2016
    Publication date: August 4, 2016
    Inventor: James C. Copeland
  • Patent number: 7374905
    Abstract: The present invention is directed to a medium, broth or agar, and a method of utilizing the same, in order to isolate and/or identify anaerobes from a mixed sample that contains facultative microorganisms. The medium contains an inhibitor of the electron transport system, such as a salt of azide (N3?), cyanide (CN?) or related compounds. These inhibitors are present in an amount sufficient to limit the growth of facultative microorganisms under anaerobic conditions while not inhibiting the growth of the anaerobe microorganisms. Preferably, the inhibitor is present in the amount of from about 0.1 mg/ml to about 1.0 mg/ml in broth medium, and from about 0.01 mg/ml to 1.0 mg/ml in agar medium.
    Type: Grant
    Filed: November 8, 2001
    Date of Patent: May 20, 2008
    Assignee: Oxyrase, Inc.
    Inventors: James C. Copeland, Kathy J. Myers
  • Publication number: 20030138867
    Abstract: The present invention is directed to a medium, broth or agar, and a method of utilizing the same, in order to isolate and/or identify anaerobes from a mixed sample that contains facultative microorganisms. The medium contains an inhibitor of the electron transport system, such as a salt of azide (N3−), cyanide (CN−) or related compounds. These inhibitors are present in an amount sufficient to limit the growth of facultative microorganisms under anaerobic conditions while not inhibiting the growth of the anaerobe microorganisms. Preferably, the inhibitor is present in the amount of from about 0.1 mg/ml to about 1.0 mg/ml in broth medium, and from about 0.01 mg/ml to 1.0 mg/ml in agar medium.
    Type: Application
    Filed: November 8, 2001
    Publication date: July 24, 2003
    Inventors: James C. Copeland, Kathy J. Myers
  • Publication number: 20030104608
    Abstract: The present invention is directed to a novel method, composition and device for removing dissolved oxygen from solutions containing alcohols and/or acids. By removing oxygen from various products, the present invention is an effective antioxidant for beverages and food products, as well as for industrial and commercial solutions containing alcohols and/or acids.
    Type: Application
    Filed: March 9, 1993
    Publication date: June 5, 2003
    Applicant: Oxyrase, Inc.
    Inventors: JAMES C. COPELAND, HOWARD I. ADLER, WELDON D. CROW
  • Patent number: 6429008
    Abstract: An apparatus for growing anaerobic microorganisms is provided having a dish top that contains a sealing ring upon which the media surface in the dish bottom rests when the apparatus is inverted. The contact between the sealing ring and the media surface forms a seal that traps the gas in the headspace between the media surface and the inside of the dish top. A oxygen reducing agent can also be incorporated into the media together, in some instances, with a substrate which react with oxygen in the media and with oxygen in the headspace thereby creating an environment suitable for growing anaerobic, microaerophilic and facultative anaerobic microorganisms.
    Type: Grant
    Filed: March 19, 2001
    Date of Patent: August 6, 2002
    Assignee: Oxyrase, Inc.
    Inventors: James C. Copeland, Howard I. Adler, Gerald E. Spady
  • Publication number: 20020045245
    Abstract: An apparatus for growing anaerobic microorganisms is provided having a dish top that contains a sealing ring upon which the media surface in the dish bottom rests when the apparatus is inverted. The contact between the sealing ring and the media surface forms a seal that traps the gas in the headspace between the media surface and the inside of the dish top. A oxygen reducing agent can also be incorporated into the media together, in some instances, with a substrate which react with oxygen in the media and with oxygen in the headspace thereby creating an environment suitable for growing anaerobic, microaerophilic and facultative anaerobic microorganisms.
    Type: Application
    Filed: March 19, 2001
    Publication date: April 18, 2002
    Applicant: Oxyrase, Inc.
    Inventors: James C. Copeland, Howard I. Adler, Gerald E. Spady
  • Patent number: 6204051
    Abstract: An apparatus for growing anaerobic microorganisms is provided having a dish top that contains a sealing ring upon which the media surface in the dish bottom rests when the apparatus is inverted. The contact between the sealing ring and the media surface forms a seal that traps the gas in the headspace between the media surface and the inside of the dish top. A oxygen reducing agent can also be incorporated into the media together, in some instances, with a substrate which react with oxygen in the media and with oxygen in the headspace thereby creating an environment suitable for growing anaerobic, microaerophilic and facultative anaerobic microorganisms.
    Type: Grant
    Filed: May 28, 1999
    Date of Patent: March 20, 2001
    Assignee: Oxyrase, Inc.
    Inventors: James C. Copeland, Howard I. Adler, Gerald E. Spady
  • Patent number: 5955344
    Abstract: An apparatus for growing anaerobic microorganisms is provided having a dish top that contains a sealing ring upon which the media surface in the dish bottom rests when the apparatus is inverted. The contact between the sealing ring and the media surface forms a seal that traps the gas in the headspace between the media surface and the inside of the dish top. A oxygen reducing agent can also be incorporated into the media together, in some instances, with a substrate which react with oxygen in the media and with oxygen in the headspace thereby creating an environment suitable for growing anaerobic, microaerophilic and facultative anaerobic microorganisms.
    Type: Grant
    Filed: November 3, 1997
    Date of Patent: September 21, 1999
    Assignee: Oxyrase, Inc.
    Inventors: James C. Copeland, Howard I. Adler, Gerald E. Spady
  • Patent number: D563560
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: March 4, 2008
    Assignee: Oxyrase, Inc.
    Inventor: James C. Copeland