Patents by Inventor James C. Crookston

James C. Crookston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Topical compositions and methods of detection and treatment
    Patent number: 10758630
    Abstract: A topical composition includes a nanoemulsion of a plurality of hydrophobic particles having a hydrophilic coating therein. The hydrophobic particles are derived from the same or different hydrophobic material and each hydrophobic particle has a melting point below the melting point of the respective hydrophobic material. The hydrophobic particles comprise a mean particle size of less than about 10 nm, and the nanoemulsion further includes one or more pharmaceutically active agents.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: September 1, 2020
    Assignee: The Johns Hopkins University
    Inventors: Jennifer L. Sample, Julia B. Patrone, Jason J. Benkoski, Jennifer L. Breidenich, Lisa A. Kelly, Huong Le, James C. Crookston, Marcia W. Patchan, Luis Garza, Xiomara Calderon-Colon, Joshua T. Wolfe, Mellisa L. Theodore, Amanda Nelson, Sewon Kang
  • Topical Compositions and Methods of Detection and Treatment
    Publication number: 20120039814
    Abstract: A topical composition includes a nanoemulsion of a plurality of hydrophobic particles having a hydrophilic coating therein. The hydrophobic particles are derived from the same or different hydrophobic material and each hydrophobic particle has a melting point below the melting point of the respective hydrophobic material. The nanoemulsion further includes one or more pharmaceutically active agents and/or one or more chemiluminescent disease-detecting systems.
    Type: Application
    Filed: August 12, 2011
    Publication date: February 16, 2012
    Inventors: Jennifer L. Sample, Julia B. Patrone, Jason J. Benkoski, James C. Crookston, Huong Le, Jennifer L. Breidenich, Lisa A. Kelly
  • Automated epifluorescence microscopy for detection of bacterial contamination in platelets
    Patent number: 6803208
    Abstract: A method for determining the presence of bacteria in a platelet or red blood cell sample is disclosed. The method includes the steps of: lysing a substantial portion of the platelets or red blood cells; staining the bacteria using a membrane permeable nucleic acid stain; filtering the sample using a membrane filter with a suitable pore size so that a material containing the stained bacteria is retained on the membrane filter; and analyzing the material retained on the membrane filter using epifluorescence microscopy and/or digital image acquisition and analysis to determine the presence of bacteria in the sample. The method allows the detection of bacterial contamination in platelets or red blood cells at clinically significant levels in a relatively short period of time.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: October 12, 2004
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Mark Seaver, James C. Crookston, Stephen J. Wagner
  • Automated epifluorescence microscopy for detection of bacterial contamination in platelets
    Publication number: 20030022270
    Abstract: A method for determining the presence of bacteria in a platelet or red blood cell containing sample is disclosed. The method of the present invention includes the steps of: lysing a substantial portion of the platelets or red blood cells; staining the bacteria using a membrane permeable nucleic acid stain; filtering the sample using a membrane filter with a suitable pore size so that a material containing the stained bacteria is retained on the membrane filter; and analyzing the material retained on the membrane filter using epifluorescence microscopy and/or digital image acquisition and analysis to determine the presence of bacteria in the sample.
    Type: Application
    Filed: July 30, 2001
    Publication date: January 30, 2003
    Inventors: Mark Seaver, James C. Crookston, Stephen J. Wagner